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- W3048146733 abstract "In barely nine months, the pandemic known as COVID-19 has spread over 200 countries, affecting more than 22 million people and causing over than 786 000 deaths. Elderly people and patients with previous comorbidities such as hypertension and diabetes are at an increased risk to suffer a poor prognosis after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Although the same could be expected from patients with chronic obstructive pulmonary disease (COPD), current epidemiological data are conflicting. This could lead to a reduction of precautionary measures in these patients, in the context of a particularly complex global health crisis. Most COPD patients have a long history of smoking or exposure to other harmful particles or gases, capable of impairing pulmonary defences even years after the absence of exposure. Moreover, COPD is characterized by an ongoing immune dysfunction, which affects both pulmonary and systemic cellular and molecular inflammatory mediators. Consequently, increased susceptibility to viral respiratory infections have been reported in COPD, often worsened by bacterial co-infections and leading to serious clinical outcomes. The present paper is an up-to-date review that discusses the available research regarding the implications of coronavirus infection in COPD. Although validation in large studies is still needed, COPD likely increases SARS-CoV-2 susceptibility and increases COVID-19 severity. Hence, specific mechanisms to monitor and assess COPD patients should be addressed in the current pandemic." @default.
- W3048146733 created "2020-08-13" @default.
- W3048146733 creator A5067488283 @default.
- W3048146733 date "2020-09-02" @default.
- W3048146733 modified "2023-10-16" @default.
- W3048146733 title "COVID‐19 Susceptibility in chronic obstructive pulmonary disease" @default.
- W3048146733 cites W1516970616 @default.
- W3048146733 cites W1578843000 @default.
- W3048146733 cites W1686440905 @default.
- W3048146733 cites W1966224713 @default.
- W3048146733 cites W1973599173 @default.
- W3048146733 cites W1977628719 @default.
- W3048146733 cites W1978855332 @default.
- W3048146733 cites W1984173055 @default.
- W3048146733 cites W1991648511 @default.
- W3048146733 cites W1997236105 @default.
- W3048146733 cites W1999098361 @default.
- W3048146733 cites W2001275070 @default.
- W3048146733 cites W2031033693 @default.
- W3048146733 cites W2040884453 @default.
- W3048146733 cites W2042198595 @default.
- W3048146733 cites W2042814134 @default.
- W3048146733 cites W2043909055 @default.
- W3048146733 cites W2046665605 @default.
- W3048146733 cites W2048351247 @default.
- W3048146733 cites W2050218130 @default.
- W3048146733 cites W2054076340 @default.
- W3048146733 cites W2054292226 @default.
- W3048146733 cites W205523455 @default.
- W3048146733 cites W2061084204 @default.
- W3048146733 cites W2070344109 @default.
- W3048146733 cites W2077811143 @default.
- W3048146733 cites W2088886438 @default.
- W3048146733 cites W2097805909 @default.
- W3048146733 cites W2103498418 @default.
- W3048146733 cites W2105941914 @default.
- W3048146733 cites W2110947112 @default.
- W3048146733 cites W2112692443 @default.
- W3048146733 cites W2114711469 @default.
- W3048146733 cites W2118269576 @default.
- W3048146733 cites W2127327473 @default.
- W3048146733 cites W2136170126 @default.
- W3048146733 cites W2137240917 @default.
- W3048146733 cites W2141109742 @default.
- W3048146733 cites W2144792692 @default.
- W3048146733 cites W2145823277 @default.
- W3048146733 cites W2146533975 @default.
- W3048146733 cites W2151392308 @default.
- W3048146733 cites W2152271046 @default.
- W3048146733 cites W2154153313 @default.
- W3048146733 cites W2156304629 @default.
- W3048146733 cites W2168061900 @default.
- W3048146733 cites W2168078376 @default.
- W3048146733 cites W2168998401 @default.
- W3048146733 cites W2169005508 @default.
- W3048146733 cites W2179187436 @default.
- W3048146733 cites W2224072113 @default.
- W3048146733 cites W2298641969 @default.
- W3048146733 cites W2401306489 @default.
- W3048146733 cites W2406455267 @default.
- W3048146733 cites W2409389877 @default.
- W3048146733 cites W2513060462 @default.
- W3048146733 cites W2567783638 @default.
- W3048146733 cites W2573109541 @default.
- W3048146733 cites W2619354799 @default.
- W3048146733 cites W2755987639 @default.
- W3048146733 cites W2767768217 @default.
- W3048146733 cites W2786392891 @default.
- W3048146733 cites W2788349767 @default.
- W3048146733 cites W2789324427 @default.
- W3048146733 cites W2794226421 @default.
- W3048146733 cites W2796489672 @default.
- W3048146733 cites W2806885108 @default.
- W3048146733 cites W2896970169 @default.
- W3048146733 cites W2897349269 @default.
- W3048146733 cites W2899526761 @default.
- W3048146733 cites W2902061216 @default.
- W3048146733 cites W2952579436 @default.
- W3048146733 cites W2965169119 @default.
- W3048146733 cites W2999589805 @default.
- W3048146733 cites W3001897055 @default.
- W3048146733 cites W3004280078 @default.
- W3048146733 cites W3006252254 @default.
- W3048146733 cites W3007814559 @default.
- W3048146733 cites W3008827533 @default.
- W3048146733 cites W3009799538 @default.
- W3048146733 cites W3009976289 @default.
- W3048146733 cites W3011045397 @default.
- W3048146733 cites W3011608970 @default.
- W3048146733 cites W3012320055 @default.
- W3048146733 cites W3012796370 @default.
- W3048146733 cites W3012925204 @default.
- W3048146733 cites W3014493418 @default.
- W3048146733 cites W3014792996 @default.
- W3048146733 cites W3015660580 @default.
- W3048146733 cites W3016025211 @default.
- W3048146733 cites W3016124709 @default.
- W3048146733 cites W3022950950 @default.
- W3048146733 cites W3035011439 @default.
- W3048146733 cites W3048146733 @default.