Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048150261> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3048150261 endingPage "55" @default.
- W3048150261 startingPage "45" @default.
- W3048150261 abstract "The aim of the study was to analyze the input of cytosolic and oxidative pathways of energy metabolism in ATP production of cultured cells by using FLIM and routine biochemical techniques. Fluorescent imaging of endogenous cofactors NADH and FAD demonstrated a more pronounced oxidative redox status of fibroblasts compared to tumor cells and significant differences in metabolic processes in which FAD is involved. Analysis of glucose and lactate content and absorption showed that tumor cells not only absorb glucose more intensively from the environment, but also use it more intensively during anaerobic glycolysis. Lower energy efficiency of glycolysis and FAD oxidative path and greater energy consumption is the reason for the lower concentration of ATP in tumor cells. Presumably, the prevalence of glycolytic metabolism in tumor cells could be largely determined by their hypoxic reprogramming through the PI3K/AKT/mTOR signal pathway. The results of the study suggest that correlation between intracellular consumption of glucose and cytosolic concentration of NADH may contribute to the characteristic of energy metabolism state of cultured cells and serve as the biosensor of malignant cell transformation." @default.
- W3048150261 created "2020-08-13" @default.
- W3048150261 creator A5027064592 @default.
- W3048150261 creator A5028533236 @default.
- W3048150261 creator A5048938863 @default.
- W3048150261 creator A5050657366 @default.
- W3048150261 creator A5090498797 @default.
- W3048150261 date "2020-01-01" @default.
- W3048150261 modified "2023-10-16" @default.
- W3048150261 title "A New Glance on Energy Metabolism Investigation in Cultured Cells" @default.
- W3048150261 cites W1892152977 @default.
- W3048150261 cites W2001633284 @default.
- W3048150261 cites W2024901091 @default.
- W3048150261 cites W2028953302 @default.
- W3048150261 cites W2037276225 @default.
- W3048150261 cites W2048766479 @default.
- W3048150261 cites W2074141198 @default.
- W3048150261 cites W2087294008 @default.
- W3048150261 cites W2111920179 @default.
- W3048150261 cites W2114090713 @default.
- W3048150261 cites W2119795324 @default.
- W3048150261 cites W2121115572 @default.
- W3048150261 cites W2121158677 @default.
- W3048150261 cites W2135846760 @default.
- W3048150261 cites W2160562117 @default.
- W3048150261 cites W2167537697 @default.
- W3048150261 cites W2395626624 @default.
- W3048150261 cites W2466257081 @default.
- W3048150261 cites W2496616613 @default.
- W3048150261 cites W2561585908 @default.
- W3048150261 cites W2722324655 @default.
- W3048150261 cites W2757416034 @default.
- W3048150261 cites W2795730971 @default.
- W3048150261 cites W2810266944 @default.
- W3048150261 cites W2914425862 @default.
- W3048150261 cites W2936121830 @default.
- W3048150261 cites W2945890405 @default.
- W3048150261 cites W2949850558 @default.
- W3048150261 cites W2963227068 @default.
- W3048150261 cites W2976700891 @default.
- W3048150261 cites W2999943581 @default.
- W3048150261 doi "https://doi.org/10.4236/jbm.2020.88005" @default.
- W3048150261 hasPublicationYear "2020" @default.
- W3048150261 type Work @default.
- W3048150261 sameAs 3048150261 @default.
- W3048150261 citedByCount "0" @default.
- W3048150261 crossrefType "journal-article" @default.
- W3048150261 hasAuthorship W3048150261A5027064592 @default.
- W3048150261 hasAuthorship W3048150261A5028533236 @default.
- W3048150261 hasAuthorship W3048150261A5048938863 @default.
- W3048150261 hasAuthorship W3048150261A5050657366 @default.
- W3048150261 hasAuthorship W3048150261A5090498797 @default.
- W3048150261 hasBestOaLocation W30481502611 @default.
- W3048150261 hasConcept C17093226 @default.
- W3048150261 hasConcept C181199279 @default.
- W3048150261 hasConcept C185592680 @default.
- W3048150261 hasConcept C197957613 @default.
- W3048150261 hasConcept C20251656 @default.
- W3048150261 hasConcept C55493867 @default.
- W3048150261 hasConcept C55885012 @default.
- W3048150261 hasConcept C57600042 @default.
- W3048150261 hasConcept C62231903 @default.
- W3048150261 hasConcept C79879829 @default.
- W3048150261 hasConcept C86803240 @default.
- W3048150261 hasConcept C95444343 @default.
- W3048150261 hasConcept C98539663 @default.
- W3048150261 hasConceptScore W3048150261C17093226 @default.
- W3048150261 hasConceptScore W3048150261C181199279 @default.
- W3048150261 hasConceptScore W3048150261C185592680 @default.
- W3048150261 hasConceptScore W3048150261C197957613 @default.
- W3048150261 hasConceptScore W3048150261C20251656 @default.
- W3048150261 hasConceptScore W3048150261C55493867 @default.
- W3048150261 hasConceptScore W3048150261C55885012 @default.
- W3048150261 hasConceptScore W3048150261C57600042 @default.
- W3048150261 hasConceptScore W3048150261C62231903 @default.
- W3048150261 hasConceptScore W3048150261C79879829 @default.
- W3048150261 hasConceptScore W3048150261C86803240 @default.
- W3048150261 hasConceptScore W3048150261C95444343 @default.
- W3048150261 hasConceptScore W3048150261C98539663 @default.
- W3048150261 hasIssue "08" @default.
- W3048150261 hasLocation W30481502611 @default.
- W3048150261 hasOpenAccess W3048150261 @default.
- W3048150261 hasPrimaryLocation W30481502611 @default.
- W3048150261 hasRelatedWork W2048434799 @default.
- W3048150261 hasRelatedWork W2059737190 @default.
- W3048150261 hasRelatedWork W2079598623 @default.
- W3048150261 hasRelatedWork W2091272591 @default.
- W3048150261 hasRelatedWork W2178428547 @default.
- W3048150261 hasRelatedWork W2396642158 @default.
- W3048150261 hasRelatedWork W2411254275 @default.
- W3048150261 hasRelatedWork W2412799835 @default.
- W3048150261 hasRelatedWork W3031575108 @default.
- W3048150261 hasRelatedWork W587107141 @default.
- W3048150261 hasVolume "08" @default.
- W3048150261 isParatext "false" @default.
- W3048150261 isRetracted "false" @default.
- W3048150261 magId "3048150261" @default.
- W3048150261 workType "article" @default.