Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048181941> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W3048181941 abstract "The rapid emergence of resistant Gram-negative bacteria and the limited discovery of novel antibiotic is a global healthcare challenge. Many medicinal plants with potent bioactivities have been developed for the treatment of bacterial infections. Aquilaria malaccensis exhibits wide applications from perfumes and aromatic foods ingredients and great potential in medicines. In this study, crude leaf extract of A. malaccensis was evaluated for its antibacterial activity against several pathogenic Gram-negative bacteria. The leaves were processed and extracted by Soxhlet method using ethanol as the solvent. The antibacterial activity of the crude extract was tested by disc diffusion method, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against Acinetobacter baumannii (ATCC 19606), Klebsiella pneumoniae (ATCC 10031 and ATCC 700603) and Escherichia coli (ATCC 1129). Using the optimized method, the Soxhlet extract produced a yield of 178.41 mg/g. Treatment of the extract at 200 mg/mL displayed the largest inhibition zones of 14.0 mm and 9.7 mm against A. baumannii and K. pneumoniae ATCC 10031, respectively. In contrast, against E. coli and K. pneumoniae ATCC 700603, smaller zones of inhibitions of 3.3 mm were demonstrated. The MIC values of the extract were 32 mg/mL against A. baumannii and K. pneumoniae ATCC 10031 and 64 mg/mL against E. coli and K. pneumoniae ATCC 700603. The MBC values of the extract were consistent with the MIC values for all the bacteria investigated. Overall, this study was the first to show antibacterial activity of A. malaccensis leaves extract particularly against A. baumannii and K. pneumoniae and potentially develop for the treatment of resistant bacteria." @default.
- W3048181941 created "2020-08-13" @default.
- W3048181941 creator A5007167655 @default.
- W3048181941 creator A5031631949 @default.
- W3048181941 creator A5033193259 @default.
- W3048181941 creator A5043168906 @default.
- W3048181941 creator A5061811567 @default.
- W3048181941 creator A5065217702 @default.
- W3048181941 creator A5072785541 @default.
- W3048181941 date "2020-08-07" @default.
- W3048181941 modified "2023-09-26" @default.
- W3048181941 title "Antibacterial activity of ethanolic leaf extract of Aquilaria malaccensis against multidrug-resistant Gram-negative pathogen" @default.
- W3048181941 doi "https://doi.org/10.26656/fr.2017.4(6).205" @default.
- W3048181941 hasPublicationYear "2020" @default.
- W3048181941 type Work @default.
- W3048181941 sameAs 3048181941 @default.
- W3048181941 citedByCount "0" @default.
- W3048181941 crossrefType "journal-article" @default.
- W3048181941 hasAuthorship W3048181941A5007167655 @default.
- W3048181941 hasAuthorship W3048181941A5031631949 @default.
- W3048181941 hasAuthorship W3048181941A5033193259 @default.
- W3048181941 hasAuthorship W3048181941A5043168906 @default.
- W3048181941 hasAuthorship W3048181941A5061811567 @default.
- W3048181941 hasAuthorship W3048181941A5065217702 @default.
- W3048181941 hasAuthorship W3048181941A5072785541 @default.
- W3048181941 hasBestOaLocation W30481819411 @default.
- W3048181941 hasConcept C104317684 @default.
- W3048181941 hasConcept C11636898 @default.
- W3048181941 hasConcept C176947019 @default.
- W3048181941 hasConcept C185592680 @default.
- W3048181941 hasConcept C26381139 @default.
- W3048181941 hasConcept C2776051709 @default.
- W3048181941 hasConcept C2776315533 @default.
- W3048181941 hasConcept C2777058267 @default.
- W3048181941 hasConcept C2777637488 @default.
- W3048181941 hasConcept C2778883795 @default.
- W3048181941 hasConcept C2780104969 @default.
- W3048181941 hasConcept C31903555 @default.
- W3048181941 hasConcept C4937899 @default.
- W3048181941 hasConcept C523546767 @default.
- W3048181941 hasConcept C54355233 @default.
- W3048181941 hasConcept C547475151 @default.
- W3048181941 hasConcept C55493867 @default.
- W3048181941 hasConcept C556039675 @default.
- W3048181941 hasConcept C71924100 @default.
- W3048181941 hasConcept C86803240 @default.
- W3048181941 hasConcept C89423630 @default.
- W3048181941 hasConceptScore W3048181941C104317684 @default.
- W3048181941 hasConceptScore W3048181941C11636898 @default.
- W3048181941 hasConceptScore W3048181941C176947019 @default.
- W3048181941 hasConceptScore W3048181941C185592680 @default.
- W3048181941 hasConceptScore W3048181941C26381139 @default.
- W3048181941 hasConceptScore W3048181941C2776051709 @default.
- W3048181941 hasConceptScore W3048181941C2776315533 @default.
- W3048181941 hasConceptScore W3048181941C2777058267 @default.
- W3048181941 hasConceptScore W3048181941C2777637488 @default.
- W3048181941 hasConceptScore W3048181941C2778883795 @default.
- W3048181941 hasConceptScore W3048181941C2780104969 @default.
- W3048181941 hasConceptScore W3048181941C31903555 @default.
- W3048181941 hasConceptScore W3048181941C4937899 @default.
- W3048181941 hasConceptScore W3048181941C523546767 @default.
- W3048181941 hasConceptScore W3048181941C54355233 @default.
- W3048181941 hasConceptScore W3048181941C547475151 @default.
- W3048181941 hasConceptScore W3048181941C55493867 @default.
- W3048181941 hasConceptScore W3048181941C556039675 @default.
- W3048181941 hasConceptScore W3048181941C71924100 @default.
- W3048181941 hasConceptScore W3048181941C86803240 @default.
- W3048181941 hasConceptScore W3048181941C89423630 @default.
- W3048181941 hasLocation W30481819411 @default.
- W3048181941 hasLocation W30481819412 @default.
- W3048181941 hasLocation W30481819413 @default.
- W3048181941 hasOpenAccess W3048181941 @default.
- W3048181941 hasPrimaryLocation W30481819411 @default.
- W3048181941 hasRelatedWork W11772065 @default.
- W3048181941 hasRelatedWork W14325772 @default.
- W3048181941 hasRelatedWork W15497929 @default.
- W3048181941 hasRelatedWork W17855672 @default.
- W3048181941 hasRelatedWork W23246502 @default.
- W3048181941 hasRelatedWork W27293107 @default.
- W3048181941 hasRelatedWork W31026922 @default.
- W3048181941 hasRelatedWork W33933094 @default.
- W3048181941 hasRelatedWork W7949412 @default.
- W3048181941 hasRelatedWork W3450183 @default.
- W3048181941 isParatext "false" @default.
- W3048181941 isRetracted "false" @default.
- W3048181941 magId "3048181941" @default.
- W3048181941 workType "article" @default.