FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048196916> ?p ?o ?g. }

• W3048196916 endingPage "e00192" @default.
• W3048196916 startingPage "e00192" @default.
• W3048196916 abstract "Patients with functional gastrointestinal disorders (FGIDs) are classified based on their gastrointestinal (GI) symptoms, without considering their frequent extra-GI symptoms. This study defined subgroups of patients using both GI and extra-GI symptoms and examined underlying mechanisms with fructose and lactose breath tests.Latent class analysis defined distinct clusters of patients with FGID based on their long-term GI and extra-GI symptoms. Sensory and breath gas responses after fructose and lactose ingestion were compared across symptom clusters to investigate differences in sensory function and fermentation by intestinal microbiota.Six symptom clusters were identified in 2,083 patients with FGID. Clusters were characterized mainly by GI fermentation-type (cluster 1), allergy-like (cluster 2), intense pain-accentuated GI symptoms (cluster 3), central nervous system (cluster 4), musculoskeletal (cluster 5), and generalized extra-GI (cluster 6) symptoms. In the 68% of patients with complete breath tests, the areas under the curve of GI and central nervous system symptoms after fructose and lactose ingestion differed across the clusters (P < 0.001). The clusters with extensive long-term extra-GI symptoms had greater symptoms after the sugars and were predominantly women, with family or childhood allergy histories. Importantly, the areas under the curves of hydrogen and methane breath concentrations were similar (P > 0.05) across all symptom clusters. Rome III criteria did not distinguish between the symptom clusters.Patients with FGID fall into clusters defined extensively by extra-GI symptoms. Greater extra-GI symptoms are associated with evidence of generalized sensory hypersensitivity to sugar ingestion, unrelated to intestinal gas production. Possible underlying mechanisms include metabolites originating from the intestinal microbiota and somatization." @default.
• W3048196916 created "2020-08-13" @default.
• W3048196916 creator A5023802517 @default.
• W3048196916 creator A5058714238 @default.
• W3048196916 creator A5064581827 @default.
• W3048196916 creator A5066377697 @default.
• W3048196916 date "2020-08-01" @default.
• W3048196916 modified "2023-09-25" @default.
• W3048196916 title "Extragastrointestinal Symptoms and Sensory Responses During Breath Tests Distinguish Patients With Functional Gastrointestinal Disorders" @default.
• W3048196916 cites W1490631681 @default.
• W3048196916 cites W1563793761 @default.
• W3048196916 cites W1583810301 @default.
• W3048196916 cites W1897161389 @default.
• W3048196916 cites W197331058 @default.
• W3048196916 cites W1986792124 @default.
• W3048196916 cites W1988415769 @default.
• W3048196916 cites W2003946813 @default.
• W3048196916 cites W2013710222 @default.
• W3048196916 cites W2017903078 @default.
• W3048196916 cites W2024226754 @default.
• W3048196916 cites W2031466583 @default.
• W3048196916 cites W2033580411 @default.
• W3048196916 cites W2039365288 @default.
• W3048196916 cites W2040015969 @default.
• W3048196916 cites W2040248009 @default.
• W3048196916 cites W2044044822 @default.
• W3048196916 cites W2045431945 @default.
• W3048196916 cites W2064375056 @default.
• W3048196916 cites W2079239490 @default.
• W3048196916 cites W2086351101 @default.
• W3048196916 cites W2107026046 @default.
• W3048196916 cites W2107869127 @default.
• W3048196916 cites W2114718043 @default.
• W3048196916 cites W2120103608 @default.
• W3048196916 cites W2123832153 @default.
• W3048196916 cites W2145558296 @default.
• W3048196916 cites W2166102321 @default.
• W3048196916 cites W2337071383 @default.
• W3048196916 cites W2344812785 @default.
• W3048196916 cites W2404939443 @default.
• W3048196916 cites W2494623578 @default.
• W3048196916 cites W2497884722 @default.
• W3048196916 cites W2566291939 @default.
• W3048196916 cites W2568352511 @default.
• W3048196916 cites W2589886432 @default.
• W3048196916 cites W2593590937 @default.
• W3048196916 cites W2594572760 @default.
• W3048196916 cites W2601950088 @default.
• W3048196916 cites W2717823740 @default.
• W3048196916 cites W2770725052 @default.
• W3048196916 cites W2781963884 @default.
• W3048196916 cites W2783562019 @default.
• W3048196916 cites W2792961727 @default.
• W3048196916 cites W2793573099 @default.
• W3048196916 cites W2884024979 @default.
• W3048196916 cites W2884101926 @default.
• W3048196916 cites W2891260524 @default.
• W3048196916 cites W2898162003 @default.
• W3048196916 cites W2899672407 @default.
• W3048196916 cites W2900228356 @default.
• W3048196916 cites W2910008104 @default.
• W3048196916 cites W2936108149 @default.
• W3048196916 cites W4211260924 @default.
• W3048196916 doi "https://doi.org/10.14309/ctg.0000000000000192" @default.
• W3048196916 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7431249" @default.
• W3048196916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32955198" @default.
• W3048196916 hasPublicationYear "2020" @default.
• W3048196916 type Work @default.
• W3048196916 sameAs 3048196916 @default.
• W3048196916 citedByCount "2" @default.
• W3048196916 countsByYear W30481969162022 @default.
• W3048196916 countsByYear W30481969162023 @default.
• W3048196916 crossrefType "journal-article" @default.
• W3048196916 hasAuthorship W3048196916A5023802517 @default.
• W3048196916 hasAuthorship W3048196916A5058714238 @default.
• W3048196916 hasAuthorship W3048196916A5064581827 @default.
• W3048196916 hasAuthorship W3048196916A5066377697 @default.
• W3048196916 hasBestOaLocation W30481969161 @default.
• W3048196916 hasConcept C126322002 @default.
• W3048196916 hasConcept C164866538 @default.
• W3048196916 hasConcept C193230392 @default.
• W3048196916 hasConcept C199360897 @default.
• W3048196916 hasConcept C2778271842 @default.
• W3048196916 hasConcept C2779802037 @default.
• W3048196916 hasConcept C2780955771 @default.
• W3048196916 hasConcept C41008148 @default.
• W3048196916 hasConcept C71924100 @default.
• W3048196916 hasConcept C90924648 @default.
• W3048196916 hasConceptScore W3048196916C126322002 @default.
• W3048196916 hasConceptScore W3048196916C164866538 @default.
• W3048196916 hasConceptScore W3048196916C193230392 @default.
• W3048196916 hasConceptScore W3048196916C199360897 @default.
• W3048196916 hasConceptScore W3048196916C2778271842 @default.
• W3048196916 hasConceptScore W3048196916C2779802037 @default.
• W3048196916 hasConceptScore W3048196916C2780955771 @default.
• W3048196916 hasConceptScore W3048196916C41008148 @default.
• W3048196916 hasConceptScore W3048196916C71924100 @default.
• W3048196916 hasConceptScore W3048196916C90924648 @default.

• next