FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048237360> ?p ?o ?g. }

• W3048237360 endingPage "919" @default.
• W3048237360 startingPage "910" @default.
• W3048237360 abstract "A recently published randomized controlled trial has demonstrated that in patients with endometrial cancer with high-risk features, the addition of chemotherapy to radiation therapy, compared with radiation therapy alone, resulted in a significant improvement in failure-free survival. However, in the study, the effect of chemotherapy was limited to stage III patients, and the benefit was less pronounced in stage I and II patients. Our study aims to investigate the current practice of treatment and clinical outcomes in stage I high-risk endometrioid-type endometrial cancer.A single-center retrospective study was conducted on patients with stage I high-risk endometrioid-type endometrial cancer without serous or clear cell features who have undergone hysterectomy between 1998 and 2015. Data on patients, tumor, and treatments were collected and correlated with clinical outcomes.A total of 1,572 patients with stage I disease were identified and 46 patients who met the inclusion criteria were selected for final analysis. The median age at diagnosis was 63 years (range, 49-86 years) and median follow-up was 5.9 years. Among the entire cohort, 40 (87.0%) patients underwent adjuvant radiation therapy, of which 36 (78.2%) patients underwent external beam radiation therapy and 4 (8.7%) patients underwent vaginal brachytherapy. Two of the 40 patients who received adjuvant radiation therapy also received adjuvant chemotherapy. Six (13.0%) patients received no adjuvant treatment. Of the 46 patients, the cumulative risk of distant recurrence was 19.6%, and only 1 patient (2.2%) recurred within pelvis (perirectal lymph node). Five-year disease-free survival and overall survival rates were 73.1% and 80.1%, respectively.Adjuvant radiation therapy in stage I endometrioid-type endometrial cancer patients with high-risk features resulted in high rates of locoregional disease control, and most recurrences occurred at distant sites. Effective systemic therapy may be indicated in this patient population to further reduce the risk of distant relapses and improve survival." @default.
• W3048237360 created "2020-08-13" @default.
• W3048237360 creator A5007793619 @default.
• W3048237360 creator A5013744742 @default.
• W3048237360 creator A5027382545 @default.
• W3048237360 creator A5031453761 @default.
• W3048237360 creator A5044981365 @default.
• W3048237360 creator A5058581609 @default.
• W3048237360 creator A5058643611 @default.
• W3048237360 creator A5081079200 @default.
• W3048237360 date "2020-09-01" @default.
• W3048237360 modified "2023-10-16" @default.
• W3048237360 title "Treatment of Early Stage High-Risk Endometrioid-Type Endometrial Cancer and Patterns of Disease Relapse: A Retrospective Analysis" @default.
• W3048237360 cites W1457402367 @default.
• W3048237360 cites W1630482321 @default.
• W3048237360 cites W1865946714 @default.
• W3048237360 cites W1975352300 @default.
• W3048237360 cites W1975654270 @default.
• W3048237360 cites W1983141457 @default.
• W3048237360 cites W1986418310 @default.
• W3048237360 cites W1994930432 @default.
• W3048237360 cites W2016558284 @default.
• W3048237360 cites W2031309363 @default.
• W3048237360 cites W2032551985 @default.
• W3048237360 cites W2038011108 @default.
• W3048237360 cites W2041440766 @default.
• W3048237360 cites W2054791534 @default.
• W3048237360 cites W2060456031 @default.
• W3048237360 cites W2081378712 @default.
• W3048237360 cites W2096055270 @default.
• W3048237360 cites W2097409147 @default.
• W3048237360 cites W2107876586 @default.
• W3048237360 cites W2108556797 @default.
• W3048237360 cites W2109132905 @default.
• W3048237360 cites W2114222627 @default.
• W3048237360 cites W2119607431 @default.
• W3048237360 cites W2123052456 @default.
• W3048237360 cites W2123202376 @default.
• W3048237360 cites W2123879605 @default.
• W3048237360 cites W2137311408 @default.
• W3048237360 cites W2143212830 @default.
• W3048237360 cites W2147101451 @default.
• W3048237360 cites W2170352208 @default.
• W3048237360 cites W2174510671 @default.
• W3048237360 cites W2182915546 @default.
• W3048237360 cites W2468311487 @default.
• W3048237360 cites W2610555976 @default.
• W3048237360 cites W2612419201 @default.
• W3048237360 cites W2787725515 @default.
• W3048237360 cites W2793566573 @default.
• W3048237360 cites W2794053055 @default.
• W3048237360 cites W2794839527 @default.
• W3048237360 cites W2811093662 @default.
• W3048237360 cites W2885205220 @default.
• W3048237360 cites W2937778512 @default.
• W3048237360 cites W2955426005 @default.
• W3048237360 cites W2984812401 @default.
• W3048237360 cites W2997471184 @default.
• W3048237360 cites W3001195345 @default.
• W3048237360 cites W4238246955 @default.
• W3048237360 doi "https://doi.org/10.1016/j.adro.2020.07.010" @default.
• W3048237360 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7557164" @default.
• W3048237360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33083653" @default.
• W3048237360 hasPublicationYear "2020" @default.
• W3048237360 type Work @default.
• W3048237360 sameAs 3048237360 @default.
• W3048237360 citedByCount "2" @default.
• W3048237360 countsByYear W30482373602021 @default.
• W3048237360 countsByYear W30482373602022 @default.
• W3048237360 crossrefType "journal-article" @default.
• W3048237360 hasAuthorship W3048237360A5007793619 @default.
• W3048237360 hasAuthorship W3048237360A5013744742 @default.
• W3048237360 hasAuthorship W3048237360A5027382545 @default.
• W3048237360 hasAuthorship W3048237360A5031453761 @default.
• W3048237360 hasAuthorship W3048237360A5044981365 @default.
• W3048237360 hasAuthorship W3048237360A5058581609 @default.
• W3048237360 hasAuthorship W3048237360A5058643611 @default.
• W3048237360 hasAuthorship W3048237360A5081079200 @default.
• W3048237360 hasBestOaLocation W30482373601 @default.
• W3048237360 hasConcept C121608353 @default.
• W3048237360 hasConcept C126322002 @default.
• W3048237360 hasConcept C141071460 @default.
• W3048237360 hasConcept C143998085 @default.
• W3048237360 hasConcept C146357865 @default.
• W3048237360 hasConcept C151730666 @default.
• W3048237360 hasConcept C167135981 @default.
• W3048237360 hasConcept C2777088508 @default.
• W3048237360 hasConcept C2777416452 @default.
• W3048237360 hasConcept C2777982462 @default.
• W3048237360 hasConcept C2779494336 @default.
• W3048237360 hasConcept C509974204 @default.
• W3048237360 hasConcept C71924100 @default.
• W3048237360 hasConcept C86803240 @default.
• W3048237360 hasConceptScore W3048237360C121608353 @default.
• W3048237360 hasConceptScore W3048237360C126322002 @default.
• W3048237360 hasConceptScore W3048237360C141071460 @default.
• W3048237360 hasConceptScore W3048237360C143998085 @default.
• W3048237360 hasConceptScore W3048237360C146357865 @default.

• next