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• W3048258305 abstract "Long acting bronchodilators are nowadays the central treatment for management of stable COPD. Several combinations exist within the market with different formulation devices. This article reviews a recent dual combination of glycopyrronium and formoterol fumarate in an innovative pMDI-fixed dual combination, Bevespi® Aerosphere.This article explored the literature to understand the place of this novel combination and unique delivery drug device in today's therapeutic arsenal. Clinical efficacy and safety have been evaluated through the different clinical trials published in public databases.Within the fixed-dose combinations, Glycopyrrolate and formoterol fumarate offer a credible unique pMDI option to be given twice a day. LABA-LAMA offers an ICS-free alternative in COPD pharmacology which represents an important treatment option given the current debate over whether or not, maintenance triple therapy combined with ICS are benefic in the long term." @default.
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• W3048258305 date "2020-10-12" @default.
• W3048258305 modified "2023-09-25" @default.
• W3048258305 title "Glycopyrrolate and formoterol fumarate for the treatment of COPD" @default.
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• W3048258305 doi "https://doi.org/10.1080/17476348.2020.1807946" @default.
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