FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048266955> ?p ?o ?g. }

• W3048266955 abstract "<h3>Introduction</h3> There has been limited evidence on the influence of racial background in stroke outcomes in COVID-19. Underlying biological, genetic, or epigenetic characteristics may predispose to health differences and outcomes. Social determinants of health, access and geographical differences pertaining both to population density and other location-based factors may also be important. <h3>Methods</h3> We report 69 cases of acute stroke in patients positive for SARS-CoV-2, including 27 of African American background and 42 of other racial backgrounds, including Caucasian, Hispanic, and Asian. All patients presented to 14 major hospitals in the United States and Canada, from March 14-April 14, 2020. All patients had nasopharyngeal swab samples that were positive for SARS-CoV-2 on qualitative RT-PCR assays. We present a dichotomized analysis of ischemic stroke outcomes between patients of African American background as reported on hospital intake questionnaire versus all other backgrounds. <h3>Results</h3> Comparison between Caucasian, Hispanic and Asian backgrounds did not show disparities in stroke outcomes. We found no significant difference in age (64.4 versus 62.9 years) or the proportion of females (51.9% versus 38.1%) (table 1). Diabetes mellitus was present significantly less in African American cases versus others (37% vs. 66.7%). No significant difference between groups was found regarding other comorbidities including smoking, atrial fibrillation, prior anticoagulation, coronary artery disease, congestive heart failure, hypertension, hyperlipidemia, cerebrovascular accident, peripheral vascular disease, or chronic kidney disease. With respect to presenting SARS-CoV-2 symptoms, we found no difference in exposure history, asymptomatic cases, fever, cough, dyspnea, nausea or vomiting, chills, malaise, or lethargy. The African American cohort had a similar mean NIHSS score of 16.3 compared with 14.9 in other races (p=0.63). The door-to-CT time was also similar (23 versus 19 minutes). The proportion of patients presenting with a large vessel occlusion was not significantly different (40.7% versus 47%). We noted 14.8% of African American cases received intravenous tPA compared to 31% in other races, but this was not significantly different in this sample. The proportion of thrombectomy cases mirrored this (14.8% versus 31%). Laboratory findings were not significantly different between African Americans and all others. Regarding stroke functional outcomes, there was no difference between African Americans and other races in terms of discharge mRS (p=0.27). For mRS 0–2, there was no significant difference noted (14.8% versus 16.7%). Symptomatic intracranial hemorrhage (sICH) was significantly higher for African Americans (11.1% versus 3%, p<0.001). Mortality was significantly higher in African Americans compared to other races (51.9% vs. 28.6%, p=0.03). <h3>Discussion</h3> Our preliminary data suggest that there may be a mortality difference amongst stroke patients of African American background afflicted with COVID-19. The reasons for increased mortality in African Americans with COVID-19-associated stroke are unknown. Racial disparities in case counts and outcomes during the COVID-19 pandemic have been highlighted, particularly regarding African American communities. In addition, the finding in this study that mortality rate of COVID-19 positive stroke patients is greater than that previously reported in either COVID-19 respiratory infection alone or acute ischemic stroke alone, suggests an interaction that also warrants further study. <h3>Disclosures</h3> <b>A. Dmytriw:</b> None. <b>K. Phan:</b> None. <b>C. Schirmer:</b> None. <b>F. Settecase:</b> None. <b>M. Heran:</b> None. <b>A. Efendizade:</b> None. <b>A. Kuhn:</b> None. <b>A. Puri:</b> None. <b>B. Menon:</b> None. <b>M. Dibas:</b> None. <b>S. Sivakumar:</b> None. <b>A. Mowla:</b> None. <b>L. Leung:</b> None. <b>A. Malek:</b> None. <b>B. Voetsch:</b> None. <b>S. Segal:</b> None. <b>A. Wakhloo:</b> None. <b>H. Wu:</b> None. <b>A. Xavier:</b> None. <b>A. Tiwari:</b> None." @default.
• W3048266955 created "2020-08-13" @default.
• W3048266955 creator A5004041325 @default.
• W3048266955 creator A5004334483 @default.
• W3048266955 creator A5009455397 @default.
• W3048266955 creator A5012979601 @default.
• W3048266955 creator A5015909799 @default.
• W3048266955 creator A5017351355 @default.
• W3048266955 creator A5026755619 @default.
• W3048266955 creator A5042094149 @default.
• W3048266955 creator A5042660769 @default.
• W3048266955 creator A5046638368 @default.
• W3048266955 creator A5053919930 @default.
• W3048266955 creator A5053975875 @default.
• W3048266955 creator A5055424750 @default.
• W3048266955 creator A5058323338 @default.
• W3048266955 creator A5064986803 @default.
• W3048266955 creator A5073112941 @default.
• W3048266955 creator A5080305729 @default.
• W3048266955 creator A5086569685 @default.
• W3048266955 creator A5086988650 @default.
• W3048266955 creator A5090719172 @default.
• W3048266955 date "2020-08-01" @default.
• W3048266955 modified "2023-09-26" @default.
• W3048266955 title "LB-003 Ischemic stroke associated with covid-19 and racial outcome disparity in North America" @default.
• W3048266955 doi "https://doi.org/10.1136/neurintsurg-2020-snis.275" @default.
• W3048266955 hasPublicationYear "2020" @default.
• W3048266955 type Work @default.
• W3048266955 sameAs 3048266955 @default.
• W3048266955 citedByCount "0" @default.
• W3048266955 crossrefType "proceedings-article" @default.
• W3048266955 hasAuthorship W3048266955A5004041325 @default.
• W3048266955 hasAuthorship W3048266955A5004334483 @default.
• W3048266955 hasAuthorship W3048266955A5009455397 @default.
• W3048266955 hasAuthorship W3048266955A5012979601 @default.
• W3048266955 hasAuthorship W3048266955A5015909799 @default.
• W3048266955 hasAuthorship W3048266955A5017351355 @default.
• W3048266955 hasAuthorship W3048266955A5026755619 @default.
• W3048266955 hasAuthorship W3048266955A5042094149 @default.
• W3048266955 hasAuthorship W3048266955A5042660769 @default.
• W3048266955 hasAuthorship W3048266955A5046638368 @default.
• W3048266955 hasAuthorship W3048266955A5053919930 @default.
• W3048266955 hasAuthorship W3048266955A5053975875 @default.
• W3048266955 hasAuthorship W3048266955A5055424750 @default.
• W3048266955 hasAuthorship W3048266955A5058323338 @default.
• W3048266955 hasAuthorship W3048266955A5064986803 @default.
• W3048266955 hasAuthorship W3048266955A5073112941 @default.
• W3048266955 hasAuthorship W3048266955A5080305729 @default.
• W3048266955 hasAuthorship W3048266955A5086569685 @default.
• W3048266955 hasAuthorship W3048266955A5086988650 @default.
• W3048266955 hasAuthorship W3048266955A5090719172 @default.
• W3048266955 hasBestOaLocation W30482669551 @default.
• W3048266955 hasConcept C126322002 @default.
• W3048266955 hasConcept C127413603 @default.
• W3048266955 hasConcept C134018914 @default.
• W3048266955 hasConcept C138816342 @default.
• W3048266955 hasConcept C142724271 @default.
• W3048266955 hasConcept C164705383 @default.
• W3048266955 hasConcept C187212893 @default.
• W3048266955 hasConcept C2250968 @default.
• W3048266955 hasConcept C2779134260 @default.
• W3048266955 hasConcept C2779161974 @default.
• W3048266955 hasConcept C2780645631 @default.
• W3048266955 hasConcept C2908647359 @default.
• W3048266955 hasConcept C555293320 @default.
• W3048266955 hasConcept C71924100 @default.
• W3048266955 hasConcept C78519656 @default.
• W3048266955 hasConcept C99454951 @default.
• W3048266955 hasConceptScore W3048266955C126322002 @default.
• W3048266955 hasConceptScore W3048266955C127413603 @default.
• W3048266955 hasConceptScore W3048266955C134018914 @default.
• W3048266955 hasConceptScore W3048266955C138816342 @default.
• W3048266955 hasConceptScore W3048266955C142724271 @default.
• W3048266955 hasConceptScore W3048266955C164705383 @default.
• W3048266955 hasConceptScore W3048266955C187212893 @default.
• W3048266955 hasConceptScore W3048266955C2250968 @default.
• W3048266955 hasConceptScore W3048266955C2779134260 @default.
• W3048266955 hasConceptScore W3048266955C2779161974 @default.
• W3048266955 hasConceptScore W3048266955C2780645631 @default.
• W3048266955 hasConceptScore W3048266955C2908647359 @default.
• W3048266955 hasConceptScore W3048266955C555293320 @default.
• W3048266955 hasConceptScore W3048266955C71924100 @default.
• W3048266955 hasConceptScore W3048266955C78519656 @default.
• W3048266955 hasConceptScore W3048266955C99454951 @default.
• W3048266955 hasLocation W30482669551 @default.
• W3048266955 hasOpenAccess W3048266955 @default.
• W3048266955 hasPrimaryLocation W30482669551 @default.
• W3048266955 hasRelatedWork W1967841144 @default.
• W3048266955 hasRelatedWork W2018480046 @default.
• W3048266955 hasRelatedWork W2064495796 @default.
• W3048266955 hasRelatedWork W2319489406 @default.
• W3048266955 hasRelatedWork W2333279585 @default.
• W3048266955 hasRelatedWork W2603808924 @default.
• W3048266955 hasRelatedWork W2763816051 @default.
• W3048266955 hasRelatedWork W2793053827 @default.
• W3048266955 hasRelatedWork W2889073610 @default.
• W3048266955 hasRelatedWork W3132289493 @default.
• W3048266955 isParatext "false" @default.
• W3048266955 isRetracted "false" @default.
• W3048266955 magId "3048266955" @default.

• next