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- W3048268476 abstract "The evolution of Yersinia pestis from its Y. pseudotuberculosis ancestor involved gene acquisition and gene losses, leading to differences in biofilm production. Characterizing the unique biofilm features of both species may provide better understanding of how each adapts to its specific niches. This study identifies a trimeric autotransporter, YadE, that promotes biofilm stability of Y. pseudotuberculosis but which has been inactivated in Y. pestis , perhaps because it is not compatible with the Hms polysaccharide that is crucial for biofilms inside fleas. We also reveal that the Rcs signaling cascade, which represses Hms expression, activates YadE in Y. pseudotuberculosis . The ability of Y. pseudotuberculosis to use polysaccharide or YadE protein for cell-cell adhesion may help it produce biofilms in different environments." @default.
- W3048268476 created "2020-08-13" @default.
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- W3048268476 date "2020-09-23" @default.
- W3048268476 modified "2023-10-05" @default.
- W3048268476 title "A Trimeric Autotransporter Enhances Biofilm Cohesiveness in Yersinia pseudotuberculosis but Not in Yersinia pestis" @default.
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- W3048268476 doi "https://doi.org/10.1128/jb.00176-20" @default.
- W3048268476 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7515243" @default.
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