Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048302577> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3048302577 endingPage "e001326" @default.
- W3048302577 startingPage "e001326" @default.
- W3048302577 abstract "Background Optimal preprocedural planning is essential to ensure successful device closure of the left atrial appendage (LAA). Design The PREDICT-LAA study is a prospective, international, multicentre, randomised controlled trial (ClinicalTrials.gov NCT04180605 ). Two hundred patients eligible for LAA closure with an Amplatzer Amulet device (Abbott, USA) will be enrolled in the study. Patients will be allocated to a computational simulation arm (experimental) or standard treatment arm (control) using a 1:1 randomisation. For patients randomised to the computational simulation arm, preprocedural planning will be based on the analysis of cardiac computed tomography (CCT)-based patient-specific computational simulations (FEops HEARTguide, Ghent, Belgium) in order to predict optimal device size and position. For patients in the control arm, preprocedural planning will be based on local practice including CCT analysis. The LAA closure procedure and postprocedural antithrombotic therapy will follow local practice in both arms. The primary endpoint of the study is incomplete LAA closure and device-related thrombus as assessed at 3 months postprocedural CCT. Secondary endpoints encompass procedural efficiency (number of devices used, number of repositioning, procedural time, radiation exposure, contrast dye), procedure-related complications within 7 days postprocedure and a composite of all-cause death and thromboembolic events at 12 months. Conclusion The objective of the PREDICT-LAA study is to test the hypothesis that a preprocedural planning for LAA closure with the Amplatzer Amulet device based on patient-specific computational simulations can result in a more efficient procedure, optimised procedural outcomes and better clinical outcomes as compared with a standard preprocedural planning. Trial registration number ClinicalTrials.gov Registry ( NCT04180605 )." @default.
- W3048302577 created "2020-08-13" @default.
- W3048302577 creator A5008815442 @default.
- W3048302577 creator A5010839101 @default.
- W3048302577 creator A5019009414 @default.
- W3048302577 creator A5025700014 @default.
- W3048302577 creator A5034792349 @default.
- W3048302577 creator A5038121885 @default.
- W3048302577 creator A5039903732 @default.
- W3048302577 creator A5041706037 @default.
- W3048302577 creator A5045476307 @default.
- W3048302577 creator A5048454229 @default.
- W3048302577 creator A5053858541 @default.
- W3048302577 creator A5059280570 @default.
- W3048302577 creator A5067027756 @default.
- W3048302577 creator A5068286741 @default.
- W3048302577 creator A5069507925 @default.
- W3048302577 date "2020-08-01" @default.
- W3048302577 modified "2023-10-16" @default.
- W3048302577 title "Value of FEops HEARTguide patient-specific computational simulations in the planning of left atrial appendage closure with the Amplatzer Amulet closure device: rationale and design of the PREDICT-LAA study" @default.
- W3048302577 cites W1992714787 @default.
- W3048302577 cites W2112970567 @default.
- W3048302577 cites W2205219833 @default.
- W3048302577 cites W2786946573 @default.
- W3048302577 cites W2808943801 @default.
- W3048302577 cites W2921711400 @default.
- W3048302577 cites W2969546870 @default.
- W3048302577 cites W2972783401 @default.
- W3048302577 cites W2982536890 @default.
- W3048302577 doi "https://doi.org/10.1136/openhrt-2020-001326" @default.
- W3048302577 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7412609" @default.
- W3048302577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32763967" @default.
- W3048302577 hasPublicationYear "2020" @default.
- W3048302577 type Work @default.
- W3048302577 sameAs 3048302577 @default.
- W3048302577 citedByCount "21" @default.
- W3048302577 countsByYear W30483025772020 @default.
- W3048302577 countsByYear W30483025772021 @default.
- W3048302577 countsByYear W30483025772022 @default.
- W3048302577 countsByYear W30483025772023 @default.
- W3048302577 crossrefType "journal-article" @default.
- W3048302577 hasAuthorship W3048302577A5008815442 @default.
- W3048302577 hasAuthorship W3048302577A5010839101 @default.
- W3048302577 hasAuthorship W3048302577A5019009414 @default.
- W3048302577 hasAuthorship W3048302577A5025700014 @default.
- W3048302577 hasAuthorship W3048302577A5034792349 @default.
- W3048302577 hasAuthorship W3048302577A5038121885 @default.
- W3048302577 hasAuthorship W3048302577A5039903732 @default.
- W3048302577 hasAuthorship W3048302577A5041706037 @default.
- W3048302577 hasAuthorship W3048302577A5045476307 @default.
- W3048302577 hasAuthorship W3048302577A5048454229 @default.
- W3048302577 hasAuthorship W3048302577A5053858541 @default.
- W3048302577 hasAuthorship W3048302577A5059280570 @default.
- W3048302577 hasAuthorship W3048302577A5067027756 @default.
- W3048302577 hasAuthorship W3048302577A5068286741 @default.
- W3048302577 hasAuthorship W3048302577A5069507925 @default.
- W3048302577 hasBestOaLocation W30483025771 @default.
- W3048302577 hasConcept C141071460 @default.
- W3048302577 hasConcept C146834321 @default.
- W3048302577 hasConcept C162324750 @default.
- W3048302577 hasConcept C164705383 @default.
- W3048302577 hasConcept C168563851 @default.
- W3048302577 hasConcept C203092338 @default.
- W3048302577 hasConcept C2777015399 @default.
- W3048302577 hasConcept C2781362458 @default.
- W3048302577 hasConcept C34447519 @default.
- W3048302577 hasConcept C71924100 @default.
- W3048302577 hasConceptScore W3048302577C141071460 @default.
- W3048302577 hasConceptScore W3048302577C146834321 @default.
- W3048302577 hasConceptScore W3048302577C162324750 @default.
- W3048302577 hasConceptScore W3048302577C164705383 @default.
- W3048302577 hasConceptScore W3048302577C168563851 @default.
- W3048302577 hasConceptScore W3048302577C203092338 @default.
- W3048302577 hasConceptScore W3048302577C2777015399 @default.
- W3048302577 hasConceptScore W3048302577C2781362458 @default.
- W3048302577 hasConceptScore W3048302577C34447519 @default.
- W3048302577 hasConceptScore W3048302577C71924100 @default.
- W3048302577 hasFunder F4320306493 @default.
- W3048302577 hasIssue "2" @default.
- W3048302577 hasLocation W30483025771 @default.
- W3048302577 hasLocation W30483025772 @default.
- W3048302577 hasOpenAccess W3048302577 @default.
- W3048302577 hasPrimaryLocation W30483025771 @default.
- W3048302577 hasRelatedWork W2169859159 @default.
- W3048302577 hasRelatedWork W2471255910 @default.
- W3048302577 hasRelatedWork W2517015656 @default.
- W3048302577 hasRelatedWork W2562398695 @default.
- W3048302577 hasRelatedWork W2599306953 @default.
- W3048302577 hasRelatedWork W2998878502 @default.
- W3048302577 hasRelatedWork W3000724560 @default.
- W3048302577 hasRelatedWork W3094206399 @default.
- W3048302577 hasRelatedWork W4306253774 @default.
- W3048302577 hasRelatedWork W605489538 @default.
- W3048302577 hasVolume "7" @default.
- W3048302577 isParatext "false" @default.
- W3048302577 isRetracted "false" @default.
- W3048302577 magId "3048302577" @default.
- W3048302577 workType "article" @default.