FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048303310> ?p ?o ?g. }

• W3048303310 abstract "Background Heparin administration in COVID-19 patients is recommended by expert consensus, although evidence about dosage, duration and efficacy are limited. We aim to investigate the association between different dosages of low molecular weight heparin (LMWH) and mortality among COVID-19 hospitalized patients. Methods and Results Retrospective study of 450 laboratory-confirmed COVID-19 patients admitted to Sant’Orsola Bologna Hospital from March 01 to April 10, 2020. Clinical, laboratory and treatment data were collected and analyzed. The in-hospital mortality between COVID-19 patients treated with standard prophylactic LMWH dosage vs intermediate LMWH dosage was compared. Out of 450 patients, 361 received standard deep vein thrombosis (DVT) prophylaxis enoxaparin treatment (40-60mg/Kg /day) and 89 patients received intermediate enoxaparin dosage (40-60 mg/Kg twice daily) for 7 days. No significant differences in the main demographic characteristics and laboratory testings at admission were observed in the two heparin regimen subgroups, except for older age and prevalence of hypertension in the group treated with “standard” prophylaxis LMWH dosage. The intermediate LMWH administration was associated with a lower in-hospital all-cause mortality compared to the “standard” prophylactic LMWH dosage (18.8% vs 5.8%, p = 0.02). This difference remained significant after adjustment with the propensity score for variables that differed significantly between the dosage groups (OR= 0.260, 95% CI 0.089 - 0.758, p=0.014). Conclusions Intermediate LMWH dosage seems to be associated with lower incidence of mortality compared to standard DVT prophylaxys in hospitalized COVID-19 patients. Our study paves the way to further pathophysiological investigations and controlled studies of anticoagulation therapy in Covid-19 disease." @default.
• W3048303310 created "2020-08-13" @default.
• W3048303310 creator A5008738017 @default.
• W3048303310 creator A5010982417 @default.
• W3048303310 creator A5030742489 @default.
• W3048303310 creator A5031481733 @default.
• W3048303310 creator A5032788350 @default.
• W3048303310 creator A5043870217 @default.
• W3048303310 creator A5045135007 @default.
• W3048303310 creator A5047544416 @default.
• W3048303310 creator A5060860597 @default.
• W3048303310 creator A5061691353 @default.
• W3048303310 creator A5076338368 @default.
• W3048303310 creator A5084550471 @default.
• W3048303310 creator A5086762192 @default.
• W3048303310 creator A5087457265 @default.
• W3048303310 date "2020-08-06" @default.
• W3048303310 modified "2023-10-17" @default.
• W3048303310 title "Preliminary Experience With Low Molecular Weight Heparin Strategy in COVID-19 Patients" @default.
• W3048303310 cites W1965078663 @default.
• W3048303310 cites W2090700732 @default.
• W3048303310 cites W2604472220 @default.
• W3048303310 cites W3001118548 @default.
• W3048303310 cites W3009577418 @default.
• W3048303310 cites W3009885589 @default.
• W3048303310 cites W3010848803 @default.
• W3048303310 cites W3012492786 @default.
• W3048303310 cites W3013486442 @default.
• W3048303310 cites W3015863623 @default.
• W3048303310 cites W3017014626 @default.
• W3048303310 cites W3023346879 @default.
• W3048303310 cites W3025123560 @default.
• W3048303310 cites W3029923949 @default.
• W3048303310 cites W3031307765 @default.
• W3048303310 cites W3043049174 @default.
• W3048303310 cites W4238813159 @default.
• W3048303310 doi "https://doi.org/10.3389/fphar.2020.01124" @default.
• W3048303310 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7424043" @default.
• W3048303310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32848743" @default.
• W3048303310 hasPublicationYear "2020" @default.
• W3048303310 type Work @default.
• W3048303310 sameAs 3048303310 @default.
• W3048303310 citedByCount "60" @default.
• W3048303310 countsByYear W30483033102020 @default.
• W3048303310 countsByYear W30483033102021 @default.
• W3048303310 countsByYear W30483033102022 @default.
• W3048303310 countsByYear W30483033102023 @default.
• W3048303310 crossrefType "journal-article" @default.
• W3048303310 hasAuthorship W3048303310A5008738017 @default.
• W3048303310 hasAuthorship W3048303310A5010982417 @default.
• W3048303310 hasAuthorship W3048303310A5030742489 @default.
• W3048303310 hasAuthorship W3048303310A5031481733 @default.
• W3048303310 hasAuthorship W3048303310A5032788350 @default.
• W3048303310 hasAuthorship W3048303310A5043870217 @default.
• W3048303310 hasAuthorship W3048303310A5045135007 @default.
• W3048303310 hasAuthorship W3048303310A5047544416 @default.
• W3048303310 hasAuthorship W3048303310A5060860597 @default.
• W3048303310 hasAuthorship W3048303310A5061691353 @default.
• W3048303310 hasAuthorship W3048303310A5076338368 @default.
• W3048303310 hasAuthorship W3048303310A5084550471 @default.
• W3048303310 hasAuthorship W3048303310A5086762192 @default.
• W3048303310 hasAuthorship W3048303310A5087457265 @default.
• W3048303310 hasBestOaLocation W30483033101 @default.
• W3048303310 hasConcept C120665830 @default.
• W3048303310 hasConcept C121332964 @default.
• W3048303310 hasConcept C126322002 @default.
• W3048303310 hasConcept C141071460 @default.
• W3048303310 hasConcept C162156334 @default.
• W3048303310 hasConcept C2776884760 @default.
• W3048303310 hasConcept C2777557582 @default.
• W3048303310 hasConcept C2778959117 @default.
• W3048303310 hasConcept C2780868729 @default.
• W3048303310 hasConcept C2781413609 @default.
• W3048303310 hasConcept C61511704 @default.
• W3048303310 hasConcept C71924100 @default.
• W3048303310 hasConceptScore W3048303310C120665830 @default.
• W3048303310 hasConceptScore W3048303310C121332964 @default.
• W3048303310 hasConceptScore W3048303310C126322002 @default.
• W3048303310 hasConceptScore W3048303310C141071460 @default.
• W3048303310 hasConceptScore W3048303310C162156334 @default.
• W3048303310 hasConceptScore W3048303310C2776884760 @default.
• W3048303310 hasConceptScore W3048303310C2777557582 @default.
• W3048303310 hasConceptScore W3048303310C2778959117 @default.
• W3048303310 hasConceptScore W3048303310C2780868729 @default.
• W3048303310 hasConceptScore W3048303310C2781413609 @default.
• W3048303310 hasConceptScore W3048303310C61511704 @default.
• W3048303310 hasConceptScore W3048303310C71924100 @default.
• W3048303310 hasLocation W30483033101 @default.
• W3048303310 hasLocation W30483033102 @default.
• W3048303310 hasLocation W30483033103 @default.
• W3048303310 hasLocation W30483033104 @default.
• W3048303310 hasOpenAccess W3048303310 @default.
• W3048303310 hasPrimaryLocation W30483033101 @default.
• W3048303310 hasRelatedWork W1818791460 @default.
• W3048303310 hasRelatedWork W1965732988 @default.
• W3048303310 hasRelatedWork W2009553540 @default.
• W3048303310 hasRelatedWork W2078625934 @default.
• W3048303310 hasRelatedWork W220073818 @default.
• W3048303310 hasRelatedWork W2203119649 @default.
• W3048303310 hasRelatedWork W2338618131 @default.

• next