Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048342353> ?p ?o ?g. }
- W3048342353 abstract "The inferior frontal lobe is an important area of the brain involved in the stress response, and higher activation with acute mental stress may indicate a more severe stress reaction. However, it is unclear if activation of this region with stress correlates with angina in individuals with coronary artery disease.Individuals with stable coronary artery disease underwent acute mental stress testing using a series of standardized speech/arithmetic stressors in conjunction with high resolution positron emission tomography imaging of the brain. Blood flow to the inferior frontal lobe was evaluated as a ratio compared with whole brain flow for each scan. Angina was assessed with the Seattle Angina Questionnaire's angina frequency subscale at baseline and 2 years follow-up.We analyzed 148 individuals with coronary artery disease (mean age [SD] 62 [8] years; 69% male, and 35.8% Black). For every doubling in the inferior frontal lobe activation, angina frequency was increased by 13.7 units at baseline ([Formula: see text], 13.7 [95% CI, 6.3-21.7]; P=0.008) and 11.6 units during follow-up ([Formula: see text], 11.6 [95% CI, 4.1-19.2]; P=0.01) in a model adjusted for baseline demographics. Mental stress-induced ischemia and activation of other brain pain processing regions (thalamus, insula, and amygdala) accounted for 40.0% and 13.1% of the total effect of inferior frontal lobe activation on angina severity, respectively.Inferior frontal lobe activation with mental stress is independently associated with angina at baseline and during follow-up. Mental stress-induced ischemia and other pain processing brain regions may play a contributory role." @default.
- W3048342353 created "2020-08-13" @default.
- W3048342353 creator A5000322709 @default.
- W3048342353 creator A5009157075 @default.
- W3048342353 creator A5032528743 @default.
- W3048342353 creator A5050828967 @default.
- W3048342353 creator A5054714854 @default.
- W3048342353 creator A5058902301 @default.
- W3048342353 creator A5073031849 @default.
- W3048342353 creator A5075681372 @default.
- W3048342353 creator A5079409870 @default.
- W3048342353 creator A5085650630 @default.
- W3048342353 date "2020-08-01" @default.
- W3048342353 modified "2023-10-16" @default.
- W3048342353 title "Association Between Mental Stress-Induced Inferior Frontal Cortex Activation and Angina in Coronary Artery Disease" @default.
- W3048342353 cites W1551696913 @default.
- W3048342353 cites W1888073748 @default.
- W3048342353 cites W1901462932 @default.
- W3048342353 cites W1989936418 @default.
- W3048342353 cites W1997103133 @default.
- W3048342353 cites W1997215119 @default.
- W3048342353 cites W2007516104 @default.
- W3048342353 cites W2027716566 @default.
- W3048342353 cites W2028309703 @default.
- W3048342353 cites W2038702827 @default.
- W3048342353 cites W2040087184 @default.
- W3048342353 cites W2040165048 @default.
- W3048342353 cites W2043525434 @default.
- W3048342353 cites W2056914680 @default.
- W3048342353 cites W2057795808 @default.
- W3048342353 cites W2062477851 @default.
- W3048342353 cites W2067995883 @default.
- W3048342353 cites W2068789655 @default.
- W3048342353 cites W2073496569 @default.
- W3048342353 cites W2083745980 @default.
- W3048342353 cites W2094767740 @default.
- W3048342353 cites W2097313012 @default.
- W3048342353 cites W2098342535 @default.
- W3048342353 cites W2108999584 @default.
- W3048342353 cites W2109647832 @default.
- W3048342353 cites W2131165483 @default.
- W3048342353 cites W2140309190 @default.
- W3048342353 cites W2144126218 @default.
- W3048342353 cites W2166351234 @default.
- W3048342353 cites W2169343422 @default.
- W3048342353 cites W2171222349 @default.
- W3048342353 cites W2176421987 @default.
- W3048342353 cites W2312888872 @default.
- W3048342353 cites W2561444630 @default.
- W3048342353 cites W2563525854 @default.
- W3048342353 cites W2625897054 @default.
- W3048342353 cites W2772670208 @default.
- W3048342353 cites W2804688904 @default.
- W3048342353 cites W2900038824 @default.
- W3048342353 cites W2916840070 @default.
- W3048342353 cites W2944713273 @default.
- W3048342353 cites W2995420431 @default.
- W3048342353 cites W3003299879 @default.
- W3048342353 cites W4376103848 @default.
- W3048342353 doi "https://doi.org/10.1161/circimaging.120.010710" @default.
- W3048342353 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7422935" @default.
- W3048342353 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32772572" @default.
- W3048342353 hasPublicationYear "2020" @default.
- W3048342353 type Work @default.
- W3048342353 sameAs 3048342353 @default.
- W3048342353 citedByCount "9" @default.
- W3048342353 countsByYear W30483423532021 @default.
- W3048342353 countsByYear W30483423532022 @default.
- W3048342353 countsByYear W30483423532023 @default.
- W3048342353 crossrefType "journal-article" @default.
- W3048342353 hasAuthorship W3048342353A5000322709 @default.
- W3048342353 hasAuthorship W3048342353A5009157075 @default.
- W3048342353 hasAuthorship W3048342353A5032528743 @default.
- W3048342353 hasAuthorship W3048342353A5050828967 @default.
- W3048342353 hasAuthorship W3048342353A5054714854 @default.
- W3048342353 hasAuthorship W3048342353A5058902301 @default.
- W3048342353 hasAuthorship W3048342353A5073031849 @default.
- W3048342353 hasAuthorship W3048342353A5075681372 @default.
- W3048342353 hasAuthorship W3048342353A5079409870 @default.
- W3048342353 hasAuthorship W3048342353A5085650630 @default.
- W3048342353 hasBestOaLocation W30483423531 @default.
- W3048342353 hasConcept C104996578 @default.
- W3048342353 hasConcept C118552586 @default.
- W3048342353 hasConcept C126322002 @default.
- W3048342353 hasConcept C15744967 @default.
- W3048342353 hasConcept C164705383 @default.
- W3048342353 hasConcept C169760540 @default.
- W3048342353 hasConcept C2777127467 @default.
- W3048342353 hasConcept C2778213512 @default.
- W3048342353 hasConcept C2778425758 @default.
- W3048342353 hasConcept C500558357 @default.
- W3048342353 hasConcept C71924100 @default.
- W3048342353 hasConceptScore W3048342353C104996578 @default.
- W3048342353 hasConceptScore W3048342353C118552586 @default.
- W3048342353 hasConceptScore W3048342353C126322002 @default.
- W3048342353 hasConceptScore W3048342353C15744967 @default.
- W3048342353 hasConceptScore W3048342353C164705383 @default.
- W3048342353 hasConceptScore W3048342353C169760540 @default.
- W3048342353 hasConceptScore W3048342353C2777127467 @default.
- W3048342353 hasConceptScore W3048342353C2778213512 @default.