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• W3048375622 abstract "Abstract Here the recognition of a single‐point mutation in oligonucleotides is described by using nanopore measurements. The translocation behavior of a series of mutated DNA strands, hybridized with a complementary DNA probe, is analyzed via blocking current and unzipping time. Discernment of the mutation position at the single nucleotide level is achieved by analysis of a 2D graph of the bootstrapped translocation data. The proposed approach provides a useful tool for the mutation detection of oligonucleotides secreted from tumor cells and is applicable in simple and label‐free diagnoses as a nanopore liquid biopsy." @default.
• W3048375622 created "2020-08-18" @default.
• W3048375622 creator A5030223874 @default.
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• W3048375622 date "2020-08-09" @default.
• W3048375622 modified "2023-10-18" @default.
• W3048375622 title "Recognition of Single‐Point Mutation Using a Biological Nanopore" @default.
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• W3048375622 doi "https://doi.org/10.1002/smtd.202000101" @default.
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