Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048379582> ?p ?o ?g. }
- W3048379582 endingPage "58" @default.
- W3048379582 startingPage "58" @default.
- W3048379582 abstract "Aging is a dynamic and progressive process that begins at conception and continues until death. This process leads to a decrease in homeostasis and morphological, biochemical and psychological changes, increasing the individual’s vulnerability to various diseases. The growth in the number of aging populations has increased the prevalence of chronic degenerative diseases, impairment of the central nervous system and dementias, such as Alzheimer’s disease, whose main risk factor is age, leading to an increase of the number of individuals who need daily support for life activities. Some theories about aging suggest it is caused by an increase of cellular senescence and reactive oxygen species, which leads to inflammation, oxidation, cell membrane damage and consequently neuronal death. Also, mitochondrial mutations, which are generated throughout the aging process, can lead to changes in energy production, deficiencies in electron transport and apoptosis induction that can result in decreased function. Additionally, increasing cellular senescence and the release of proinflammatory cytokines can cause irreversible damage to neuronal cells. Recent reports point to the importance of changing lifestyle by increasing physical exercise, improving nutrition and environmental enrichment to activate neuroprotective defense mechanisms. Therefore, this review aims to address the latest information about the different mechanisms related to neuroplasticity and neuronal death and to provide strategies that can improve neuroprotection and decrease the neurodegeneration caused by aging and environmental stressors." @default.
- W3048379582 created "2020-08-18" @default.
- W3048379582 creator A5014714880 @default.
- W3048379582 creator A5030555096 @default.
- W3048379582 creator A5032861190 @default.
- W3048379582 creator A5059704117 @default.
- W3048379582 creator A5062391480 @default.
- W3048379582 creator A5079444049 @default.
- W3048379582 creator A5084981265 @default.
- W3048379582 date "2021-01-01" @default.
- W3048379582 modified "2023-10-16" @default.
- W3048379582 title "Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process" @default.
- W3048379582 cites W1802552686 @default.
- W3048379582 cites W1881066497 @default.
- W3048379582 cites W1912652862 @default.
- W3048379582 cites W1924726292 @default.
- W3048379582 cites W1935318607 @default.
- W3048379582 cites W1967137091 @default.
- W3048379582 cites W1969331809 @default.
- W3048379582 cites W1976780320 @default.
- W3048379582 cites W1980311878 @default.
- W3048379582 cites W1986911872 @default.
- W3048379582 cites W1995376927 @default.
- W3048379582 cites W2002515881 @default.
- W3048379582 cites W2009128541 @default.
- W3048379582 cites W2014950302 @default.
- W3048379582 cites W2014965080 @default.
- W3048379582 cites W2029582543 @default.
- W3048379582 cites W2049071740 @default.
- W3048379582 cites W2050753030 @default.
- W3048379582 cites W2057204948 @default.
- W3048379582 cites W2066024318 @default.
- W3048379582 cites W2075117930 @default.
- W3048379582 cites W2081053802 @default.
- W3048379582 cites W2091263717 @default.
- W3048379582 cites W2104027449 @default.
- W3048379582 cites W2107776925 @default.
- W3048379582 cites W2115290127 @default.
- W3048379582 cites W2204209268 @default.
- W3048379582 cites W2238698772 @default.
- W3048379582 cites W2260140125 @default.
- W3048379582 cites W2270905116 @default.
- W3048379582 cites W2271127896 @default.
- W3048379582 cites W2277911925 @default.
- W3048379582 cites W2293608890 @default.
- W3048379582 cites W2307524812 @default.
- W3048379582 cites W2312903650 @default.
- W3048379582 cites W2333123302 @default.
- W3048379582 cites W2333386541 @default.
- W3048379582 cites W2345266196 @default.
- W3048379582 cites W2413177566 @default.
- W3048379582 cites W2475213970 @default.
- W3048379582 cites W2519381186 @default.
- W3048379582 cites W2525105763 @default.
- W3048379582 cites W2531562119 @default.
- W3048379582 cites W2547689139 @default.
- W3048379582 cites W2551139545 @default.
- W3048379582 cites W2553902009 @default.
- W3048379582 cites W2557816682 @default.
- W3048379582 cites W2560155445 @default.
- W3048379582 cites W2566119188 @default.
- W3048379582 cites W2567953406 @default.
- W3048379582 cites W2582042173 @default.
- W3048379582 cites W2582682511 @default.
- W3048379582 cites W2584289628 @default.
- W3048379582 cites W2587852248 @default.
- W3048379582 cites W2591947168 @default.
- W3048379582 cites W2592067246 @default.
- W3048379582 cites W2604965214 @default.
- W3048379582 cites W2605571752 @default.
- W3048379582 cites W2605674430 @default.
- W3048379582 cites W2608199474 @default.
- W3048379582 cites W2624782524 @default.
- W3048379582 cites W2624853583 @default.
- W3048379582 cites W2724782238 @default.
- W3048379582 cites W2732044567 @default.
- W3048379582 cites W2733273049 @default.
- W3048379582 cites W2733836692 @default.
- W3048379582 cites W2739438570 @default.
- W3048379582 cites W2743627045 @default.
- W3048379582 cites W2755307222 @default.
- W3048379582 cites W2760408779 @default.
- W3048379582 cites W2765965004 @default.
- W3048379582 cites W2767859551 @default.
- W3048379582 cites W2769071992 @default.
- W3048379582 cites W2770565967 @default.
- W3048379582 cites W2775892613 @default.
- W3048379582 cites W2777525962 @default.
- W3048379582 cites W2778306296 @default.
- W3048379582 cites W2782167573 @default.
- W3048379582 cites W2783778692 @default.
- W3048379582 cites W2784612915 @default.
- W3048379582 cites W2791041386 @default.
- W3048379582 cites W2791606815 @default.
- W3048379582 cites W2793567331 @default.
- W3048379582 cites W2800471507 @default.
- W3048379582 cites W2801769333 @default.
- W3048379582 cites W2804559395 @default.