Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048396027> ?p ?o ?g. }
- W3048396027 endingPage "1434" @default.
- W3048396027 startingPage "1427" @default.
- W3048396027 abstract "Introduction Patients with severe asthma experience a significant burden of symptoms, disease exacerbations and medication side-effects. Severe asthma interferes with the patients’ quality of life and has high health-care costs. New targeted biologic therapies have improved the management of severe asthma by significantly reducing exacerbations and maintenance corticosteroid use, and also improving lung function and patient quality of life.Areas covered Not all severe asthmatics are eligible for such therapies. Those with allergic and eosinophilic asthma, usually referred to as ‘T2-high’ asthma benefit from anti-IgE and anti-IL-5/5 R antibodies respectively, whereas some asthmatics are eligible for both: ‘overlap’ endotype. In this review, we present briefly the monoclonal antibodies that have been approved in the management of severe asthma and we focus on the ‘overlap’ endotype.Expert opinion Since these therapies are costly, it is extremely important to choose the right treatment for the right patient especially in the ‘overlapping’ one. The decision is mainly based on the judgment of the clinician and is often driven by the most easily obtainable biomarker, thus the blood eosinophil count. Comorbidities, patient’s input and administration frequency may aid the decision of choosing one over another biologic." @default.
- W3048396027 created "2020-08-18" @default.
- W3048396027 creator A5007486746 @default.
- W3048396027 creator A5039311118 @default.
- W3048396027 creator A5057623122 @default.
- W3048396027 creator A5059657782 @default.
- W3048396027 date "2020-08-25" @default.
- W3048396027 modified "2023-09-25" @default.
- W3048396027 title "Biologics in severe asthma: the overlap endotype - opportunities and challenges" @default.
- W3048396027 cites W1988758075 @default.
- W3048396027 cites W2027018720 @default.
- W3048396027 cites W2029587541 @default.
- W3048396027 cites W2039930386 @default.
- W3048396027 cites W2057490898 @default.
- W3048396027 cites W2062918919 @default.
- W3048396027 cites W2075699130 @default.
- W3048396027 cites W2084607526 @default.
- W3048396027 cites W2090326082 @default.
- W3048396027 cites W2095754126 @default.
- W3048396027 cites W2098276532 @default.
- W3048396027 cites W2118630839 @default.
- W3048396027 cites W2120018683 @default.
- W3048396027 cites W2121954044 @default.
- W3048396027 cites W2138355864 @default.
- W3048396027 cites W2266684950 @default.
- W3048396027 cites W2327145125 @default.
- W3048396027 cites W2339358422 @default.
- W3048396027 cites W2342693354 @default.
- W3048396027 cites W2370552689 @default.
- W3048396027 cites W2511120040 @default.
- W3048396027 cites W2513258422 @default.
- W3048396027 cites W2548196387 @default.
- W3048396027 cites W2585010481 @default.
- W3048396027 cites W2619633721 @default.
- W3048396027 cites W2627020416 @default.
- W3048396027 cites W2755078948 @default.
- W3048396027 cites W2755334065 @default.
- W3048396027 cites W2789436817 @default.
- W3048396027 cites W2803625106 @default.
- W3048396027 cites W2803941918 @default.
- W3048396027 cites W2885733809 @default.
- W3048396027 cites W2888112997 @default.
- W3048396027 cites W2896299453 @default.
- W3048396027 cites W2899608945 @default.
- W3048396027 cites W2902099490 @default.
- W3048396027 cites W2903790709 @default.
- W3048396027 cites W2913129262 @default.
- W3048396027 cites W2914723722 @default.
- W3048396027 cites W2923331274 @default.
- W3048396027 cites W2926040594 @default.
- W3048396027 cites W2943295610 @default.
- W3048396027 cites W2944657847 @default.
- W3048396027 cites W2947002828 @default.
- W3048396027 cites W2949240365 @default.
- W3048396027 cites W2971877547 @default.
- W3048396027 cites W2972178911 @default.
- W3048396027 cites W2972223372 @default.
- W3048396027 cites W3003265138 @default.
- W3048396027 cites W3007357419 @default.
- W3048396027 cites W3009366485 @default.
- W3048396027 cites W3011055151 @default.
- W3048396027 cites W3011827551 @default.
- W3048396027 cites W3014334302 @default.
- W3048396027 cites W3015668034 @default.
- W3048396027 cites W3029739424 @default.
- W3048396027 doi "https://doi.org/10.1080/14712598.2020.1809651" @default.
- W3048396027 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32779950" @default.
- W3048396027 hasPublicationYear "2020" @default.
- W3048396027 type Work @default.
- W3048396027 sameAs 3048396027 @default.
- W3048396027 citedByCount "14" @default.
- W3048396027 countsByYear W30483960272020 @default.
- W3048396027 countsByYear W30483960272021 @default.
- W3048396027 countsByYear W30483960272022 @default.
- W3048396027 crossrefType "journal-article" @default.
- W3048396027 hasAuthorship W3048396027A5007486746 @default.
- W3048396027 hasAuthorship W3048396027A5039311118 @default.
- W3048396027 hasAuthorship W3048396027A5057623122 @default.
- W3048396027 hasAuthorship W3048396027A5059657782 @default.
- W3048396027 hasConcept C126322002 @default.
- W3048396027 hasConcept C141105273 @default.
- W3048396027 hasConcept C159110408 @default.
- W3048396027 hasConcept C159654299 @default.
- W3048396027 hasConcept C177713679 @default.
- W3048396027 hasConcept C203014093 @default.
- W3048396027 hasConcept C207480886 @default.
- W3048396027 hasConcept C2776042228 @default.
- W3048396027 hasConcept C2777037409 @default.
- W3048396027 hasConcept C2777832160 @default.
- W3048396027 hasConcept C2778564945 @default.
- W3048396027 hasConcept C2779134260 @default.
- W3048396027 hasConcept C2779377019 @default.
- W3048396027 hasConcept C2779787640 @default.
- W3048396027 hasConcept C2779951463 @default.
- W3048396027 hasConcept C2780510475 @default.
- W3048396027 hasConcept C2781293274 @default.
- W3048396027 hasConcept C71924100 @default.
- W3048396027 hasConceptScore W3048396027C126322002 @default.