Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048405419> ?p ?o ?g. }
- W3048405419 endingPage "1355" @default.
- W3048405419 startingPage "1343" @default.
- W3048405419 abstract "Recurrent caries is a primary reason for restoration failure caused by biofilm acids. The objectives of this study were to: (1) develop a novel multifunctional composite with antibacterial function and calcium (Ca) and phosphate (P) ion release, and (2) investigate the effects on enamel demineralization and hardness at the margins under biofilms. Dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of amorphous calcium phosphate (NACP) were incorporated into composite. Four groups were tested: (1) Commercial control (Heliomolar), (2) Experimental control (0% DMAHDM + 0% NACP), (3) antibacterial group (3% DMAHDM + 0% NACP), (D) antibacterial and remineralizing group (3% DMAHDM + 30% NACP). Mechanical properties and Ca and P ion release were measured. Colony-forming units (CFU), lactic acid and polysaccharide of Streptococcus mutans (S. mutans) biofilms were evaluated. Demineralization of bovine enamel with restorations was induced via S. mutans, and enamel hardness was measured. Data were analyzed via one-way and two-way analyses of variance and Tukey’s multiple comparison tests. Adding DMAHDM and NACP into composite did not compromise the mechanical properties (P > 0.05). Ca and P ion release of 3% DMAHDM + 30% NACP was increased at cariogenic low pH. Biofilm lactic acid and polysaccharides were greatly decreased via DMAHDM, and CFU was reduced by 4 logs (P < 0.05). Under biofilm acids, enamel hardness at the margins was decreased to about 0.5 GPa for control; it was about 1 GPa for antibacterial group, and 1.3 GPa for antibacterial and remineralizing group (P < 0.05). The novel 3% DMAHDM + 30% NACP composite had strong antibacterial effects. It substantially reduced enamel demineralization adjacent to restorations under biofilm acid attacks, yielding enamel hardness that was 2-fold greater than that of control composites. The novel multifunctional composite is promising to inhibit recurrent caries." @default.
- W3048405419 created "2020-08-18" @default.
- W3048405419 creator A5006690496 @default.
- W3048405419 creator A5010938926 @default.
- W3048405419 creator A5012992454 @default.
- W3048405419 creator A5041624843 @default.
- W3048405419 creator A5050736907 @default.
- W3048405419 creator A5053640827 @default.
- W3048405419 creator A5062765034 @default.
- W3048405419 creator A5081161678 @default.
- W3048405419 creator A5083258987 @default.
- W3048405419 creator A5088320537 @default.
- W3048405419 date "2020-10-01" @default.
- W3048405419 modified "2023-10-07" @default.
- W3048405419 title "In vitro evaluation of composite containing DMAHDM and calcium phosphate nanoparticles on recurrent caries inhibition at bovine enamel-restoration margins" @default.
- W3048405419 cites W110975304 @default.
- W3048405419 cites W1488644503 @default.
- W3048405419 cites W1751948390 @default.
- W3048405419 cites W1911323177 @default.
- W3048405419 cites W1963874687 @default.
- W3048405419 cites W1964522126 @default.
- W3048405419 cites W1970594812 @default.
- W3048405419 cites W1978174631 @default.
- W3048405419 cites W1986338430 @default.
- W3048405419 cites W1989503034 @default.
- W3048405419 cites W1989571679 @default.
- W3048405419 cites W2000552906 @default.
- W3048405419 cites W2004172833 @default.
- W3048405419 cites W2005026821 @default.
- W3048405419 cites W2007380246 @default.
- W3048405419 cites W2010735814 @default.
- W3048405419 cites W2013635792 @default.
- W3048405419 cites W2019568353 @default.
- W3048405419 cites W2021172432 @default.
- W3048405419 cites W2024060557 @default.
- W3048405419 cites W2029454447 @default.
- W3048405419 cites W2029989802 @default.
- W3048405419 cites W2036125989 @default.
- W3048405419 cites W2043934813 @default.
- W3048405419 cites W2045621870 @default.
- W3048405419 cites W2046694944 @default.
- W3048405419 cites W2048758113 @default.
- W3048405419 cites W2050006541 @default.
- W3048405419 cites W2051208024 @default.
- W3048405419 cites W2051920775 @default.
- W3048405419 cites W2054003035 @default.
- W3048405419 cites W2055294114 @default.
- W3048405419 cites W2059994723 @default.
- W3048405419 cites W2068391276 @default.
- W3048405419 cites W2075560828 @default.
- W3048405419 cites W2078414734 @default.
- W3048405419 cites W2078579619 @default.
- W3048405419 cites W2081473747 @default.
- W3048405419 cites W2087882436 @default.
- W3048405419 cites W2102322161 @default.
- W3048405419 cites W2118293741 @default.
- W3048405419 cites W2123234512 @default.
- W3048405419 cites W2124945708 @default.
- W3048405419 cites W2124976849 @default.
- W3048405419 cites W2131314048 @default.
- W3048405419 cites W2131359149 @default.
- W3048405419 cites W2132104110 @default.
- W3048405419 cites W2133527384 @default.
- W3048405419 cites W2141749643 @default.
- W3048405419 cites W2147166009 @default.
- W3048405419 cites W2156520524 @default.
- W3048405419 cites W2161616012 @default.
- W3048405419 cites W2166449119 @default.
- W3048405419 cites W2166669634 @default.
- W3048405419 cites W2201400649 @default.
- W3048405419 cites W2398236992 @default.
- W3048405419 cites W2412467963 @default.
- W3048405419 cites W2486608294 @default.
- W3048405419 cites W2506770151 @default.
- W3048405419 cites W2541681986 @default.
- W3048405419 cites W2576446872 @default.
- W3048405419 cites W2592900587 @default.
- W3048405419 cites W2602992170 @default.
- W3048405419 cites W2616670225 @default.
- W3048405419 cites W2620987087 @default.
- W3048405419 cites W2695377043 @default.
- W3048405419 cites W2738458382 @default.
- W3048405419 cites W2750102355 @default.
- W3048405419 cites W2767983180 @default.
- W3048405419 cites W2788453331 @default.
- W3048405419 cites W2790097242 @default.
- W3048405419 cites W2793414260 @default.
- W3048405419 cites W2797771901 @default.
- W3048405419 cites W2802423713 @default.
- W3048405419 cites W2802889855 @default.
- W3048405419 cites W2928728110 @default.
- W3048405419 cites W2941974751 @default.
- W3048405419 cites W4249723987 @default.
- W3048405419 cites W760285487 @default.
- W3048405419 doi "https://doi.org/10.1016/j.dental.2020.07.007" @default.
- W3048405419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32800353" @default.
- W3048405419 hasPublicationYear "2020" @default.
- W3048405419 type Work @default.