Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048406913> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3048406913 endingPage "418" @default.
- W3048406913 startingPage "418" @default.
- W3048406913 abstract "Endometrioid-type endometrial carcinoma is the most common malignancy of the female genital tract in developed countries. The prognosis greatly depends on the grade and stage of the disease.In some patients, the disease recurs in a short time after the surgical/medical therapy. Hence, it is important to predict the patients who will have worse prognosis at the beginning, to choose the appropriate treatment; resuming the search of new prognostic markers. Therefore, our study aimed to detect trophoblast cell surface antigen 2 (TROP2) as a new prognostic marker.The patients who underwent a hysterectomy and diagnosed with endometrioid-type endometrial carcinoma were evaluated retrospectively and TROP2 immunostain was performed to their tumoral slides.We evaluated TROP2 expressions in 102 patients immunohistochemically who underwent hysterectomy with the diagnosis of endometrioid-type endometrial carcinoma histopathologically and correlated them with the other generally accepted prognostic parameters.The Kolmogorov-Smirnov test and Q-Q plot test were used to verify the normality of the distribution of continuous variables. The Chi-square/Fisher's exact tests were used for categorical variables. Analyses were performed with SPSS Statistics for Windows, Version 20.High overexpression of TROP2 was seen in larger, higher-grade, deeper-invasive tumors, tumors with vascular invasion, and pelvic-lymph-node metastasis. These results were statistically significant (P ≤ 0.05).Overexpression of TROP2 in endometrioid-type endometrial carcinoma seems to be a poor prognostic factor; it may be useful in determining the biologically more aggressive tumors before the treatment. This early determination is very important to choose the appropriate surgery, adjuvant-treatments, and follow-up." @default.
- W3048406913 created "2020-08-18" @default.
- W3048406913 creator A5001688073 @default.
- W3048406913 creator A5081991533 @default.
- W3048406913 date "2020-01-01" @default.
- W3048406913 modified "2023-10-16" @default.
- W3048406913 title "Can TROP2 be used as a prognostic marker in endometrioid endometrial carcinoma?" @default.
- W3048406913 cites W1968917525 @default.
- W3048406913 cites W1986285351 @default.
- W3048406913 cites W1993793864 @default.
- W3048406913 cites W2008029127 @default.
- W3048406913 cites W2026274236 @default.
- W3048406913 cites W2039737894 @default.
- W3048406913 cites W2041969134 @default.
- W3048406913 cites W2043144595 @default.
- W3048406913 cites W2045306661 @default.
- W3048406913 cites W2046075502 @default.
- W3048406913 cites W2112245386 @default.
- W3048406913 cites W2158891743 @default.
- W3048406913 cites W2165948908 @default.
- W3048406913 cites W2415615858 @default.
- W3048406913 cites W2515082591 @default.
- W3048406913 cites W2523492732 @default.
- W3048406913 cites W2590751956 @default.
- W3048406913 cites W2592704775 @default.
- W3048406913 cites W2772085397 @default.
- W3048406913 cites W2775392631 @default.
- W3048406913 cites W2781208253 @default.
- W3048406913 cites W2811318458 @default.
- W3048406913 cites W2863243018 @default.
- W3048406913 cites W2884890992 @default.
- W3048406913 doi "https://doi.org/10.4103/ijpm.ijpm_783_19" @default.
- W3048406913 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32769331" @default.
- W3048406913 hasPublicationYear "2020" @default.
- W3048406913 type Work @default.
- W3048406913 sameAs 3048406913 @default.
- W3048406913 citedByCount "2" @default.
- W3048406913 countsByYear W30484069132021 @default.
- W3048406913 countsByYear W30484069132022 @default.
- W3048406913 crossrefType "journal-article" @default.
- W3048406913 hasAuthorship W3048406913A5001688073 @default.
- W3048406913 hasAuthorship W3048406913A5081991533 @default.
- W3048406913 hasBestOaLocation W30484069131 @default.
- W3048406913 hasConcept C126322002 @default.
- W3048406913 hasConcept C142724271 @default.
- W3048406913 hasConcept C143998085 @default.
- W3048406913 hasConcept C146357865 @default.
- W3048406913 hasConcept C151730666 @default.
- W3048406913 hasConcept C191093355 @default.
- W3048406913 hasConcept C2777546739 @default.
- W3048406913 hasConcept C2779399171 @default.
- W3048406913 hasConcept C2779494336 @default.
- W3048406913 hasConcept C71924100 @default.
- W3048406913 hasConcept C86803240 @default.
- W3048406913 hasConceptScore W3048406913C126322002 @default.
- W3048406913 hasConceptScore W3048406913C142724271 @default.
- W3048406913 hasConceptScore W3048406913C143998085 @default.
- W3048406913 hasConceptScore W3048406913C146357865 @default.
- W3048406913 hasConceptScore W3048406913C151730666 @default.
- W3048406913 hasConceptScore W3048406913C191093355 @default.
- W3048406913 hasConceptScore W3048406913C2777546739 @default.
- W3048406913 hasConceptScore W3048406913C2779399171 @default.
- W3048406913 hasConceptScore W3048406913C2779494336 @default.
- W3048406913 hasConceptScore W3048406913C71924100 @default.
- W3048406913 hasConceptScore W3048406913C86803240 @default.
- W3048406913 hasIssue "3" @default.
- W3048406913 hasLocation W30484069131 @default.
- W3048406913 hasLocation W30484069132 @default.
- W3048406913 hasLocation W30484069133 @default.
- W3048406913 hasOpenAccess W3048406913 @default.
- W3048406913 hasPrimaryLocation W30484069131 @default.
- W3048406913 hasRelatedWork W2014435840 @default.
- W3048406913 hasRelatedWork W2356105190 @default.
- W3048406913 hasRelatedWork W2406245798 @default.
- W3048406913 hasRelatedWork W2408391279 @default.
- W3048406913 hasRelatedWork W2418946947 @default.
- W3048406913 hasRelatedWork W2468698185 @default.
- W3048406913 hasRelatedWork W2621373076 @default.
- W3048406913 hasRelatedWork W2887757321 @default.
- W3048406913 hasRelatedWork W3008856513 @default.
- W3048406913 hasRelatedWork W3140733676 @default.
- W3048406913 hasVolume "63" @default.
- W3048406913 isParatext "false" @default.
- W3048406913 isRetracted "false" @default.
- W3048406913 magId "3048406913" @default.
- W3048406913 workType "article" @default.