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- W3048449096 abstract "Most of the MAPKs activity is to stimulate a wide variety of signals which include mitogens, growth factors, cytokines, T cell antigens, pheromones, UV and ionizing radiations, osmotic stress, heat shock, oxidative stress and various other factors. MAPKs acts on most non-nuclear oncogenes and is found to be liable for growth factors response towards cellular stimuli. MAPK proteins participating in different pathways are extremely crucial in various dental and periodontal disorders with induced chronic pain. Centred on evolutionary relationships, domains detection, phosphorylated amino acid sites identification and evaluation of amino acids within the active site lining cavity, the role of MAPK 1 and 3 contributing in growth factor pathway, MAPK 8, 9 and 10 participating in stress-related pathway and MAPK 11, 12 and 13 appearing in inflammatory pathway are reported. Most of the research has concentrated on focusing MAPK 14 which is p38 MAPK isoform alpha." @default.
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- W3048449096 date "2020-08-11" @default.
- W3048449096 modified "2023-10-16" @default.
- W3048449096 title "A Comparatives Study of Protein Kinase Domain Regions for MAPK 1-14" @default.
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- W3048449096 doi "https://doi.org/10.1007/978-981-15-5400-1_38" @default.
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