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- W3048449209 abstract "Aim: To evaluate sorafenib treatment in Latin American patients with unresectable hepatocellular carcinoma in the real-world GIDEON study. Patients & methods: Sorafenib administration, safety and efficacy were analyzed by Child–Pugh status. Results: Of 90 evaluable patients (37% Child–Pugh A, 46% Child–Pugh B and 3% Child–Pugh C at study entry), 97% started sorafenib at 800 mg/day. Patients with Child–Pugh B7 had the longest median treatment duration of sorafenib (33.1 weeks). Sorafenib-related adverse events occurred in 58% of patients with Child–Pugh A (21% grade 3/4) and 46% with Child–Pugh B (7% grade 3/4). Conclusion: Sorafenib had a similar safety profile across patients with Child–Pugh A and B and is a treatment option for both groups." @default.
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- W3048449209 date "2020-11-01" @default.
- W3048449209 modified "2023-09-25" @default.
- W3048449209 title "Sorafenib treatment by Child–Pugh score in Latin American patients with hepatocellular carcinoma" @default.
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- W3048449209 doi "https://doi.org/10.2217/fon-2020-0323" @default.
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