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- W3048454702 abstract "This chapter discusses the potential that cytokines have in the enhancement of vaccine-induced immunity. Biological response modifiers that are used as adjuvants (for instance, the lipid amine Avridine) may be successful because of their ability to induce an early (IL-1) as well as a late cytokine. The chapter elucidates the action of conventional adjuvants, it becomes apparent that these activities may be replaced with cytokines. It categorizes the adjuvant effect of cytokines according to whether they have been associated with an early immune response or a late immune response. The induction of IL-1 production in macrophages by bacteria or bacterial products such as muramyl dipeptide or lipopolysaccaride has long been considered one of the major factors for the success of these compounds as adjuvants. The manner in which a particular cytokine is administered with antigen will be pivotal to ensure availability to interact with the correct target cell to induce optimal effect." @default.
- W3048454702 created "2020-08-18" @default.
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- W3048454702 date "2020-08-26" @default.
- W3048454702 modified "2023-09-26" @default.
- W3048454702 title "Potentiation of the Immune Response by Cytokines" @default.
- W3048454702 doi "https://doi.org/10.1201/9781003067382-6" @default.
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