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- W3048458691 abstract "Abstract Single chemical entities with potential to simultaneously interact with two binding sites are emerging strategies in medicinal chemistry. We have designed, synthesized and functionally characterized the first bitopic ligands for the CB 2 receptor. These compounds selectively target CB 2 versus CB 1 receptors. Their binding mode was studied by molecular dynamic simulations and site‐directed mutagenesis." @default.
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- W3048458691 date "2020-11-09" @default.
- W3048458691 modified "2023-10-14" @default.
- W3048458691 title "Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB <sub>2</sub> Receptor**" @default.
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- W3048458691 doi "https://doi.org/10.1002/chem.202003389" @default.
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