Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048475657> ?p ?o ?g. }
- W3048475657 endingPage "110058" @default.
- W3048475657 startingPage "110058" @default.
- W3048475657 abstract "Abstract Substance addiction is a chronic and complicated disease involving genetic and environmental factors. Coregulated by the above factors, perturbations of the gut microbiome have been shown to have an essential role in the development of many neuropsychiatric disorders, including addiction. However, shifts in the gut microbiome during different stages of morphine addiction remain uncharacterized. In the present study, we harvested fecal samples from mice at the acquisition (both the control and morphine groups), extinction and reinstatement stages of morphine-induced conditioned place preference (CPP). Gut microbiome profiles were detected with 16S ribosomal RNA gene sequencing. We observed an increase in community richness following morphine conditioning, and it decreased after 4 weeks of abstinence. The abundance of Verrucomicrobia increased and Bacteroides decreased at the acquisition of morphine-induced CPP, while a recovery trend was found at the extinction stage. Several discriminative genera were identified for the characterization of different stages of morphine CPP. Functional analysis of taxa with differential abundance between CPP stages was mainly enriched in the pathways of amino acid metabolism. Taken together, our findings will extend the association between dysbiosis of the gut microbiome and the opioid-induced rewarding or reinforcing behaviors." @default.
- W3048475657 created "2020-08-18" @default.
- W3048475657 creator A5004494698 @default.
- W3048475657 creator A5004524995 @default.
- W3048475657 creator A5006999345 @default.
- W3048475657 creator A5022751868 @default.
- W3048475657 creator A5065229969 @default.
- W3048475657 creator A5068819147 @default.
- W3048475657 creator A5087945074 @default.
- W3048475657 creator A5088673743 @default.
- W3048475657 date "2021-01-01" @default.
- W3048475657 modified "2023-10-16" @default.
- W3048475657 title "Differential alteration in gut microbiome profiles during acquisition, extinction and reinstatement of morphine-induced CPP" @default.
- W3048475657 cites W1821144587 @default.
- W3048475657 cites W1966164840 @default.
- W3048475657 cites W1977804070 @default.
- W3048475657 cites W1997589613 @default.
- W3048475657 cites W1999957169 @default.
- W3048475657 cites W2001339909 @default.
- W3048475657 cites W2015367177 @default.
- W3048475657 cites W2021478061 @default.
- W3048475657 cites W2024680557 @default.
- W3048475657 cites W2066848874 @default.
- W3048475657 cites W2076087096 @default.
- W3048475657 cites W2080867289 @default.
- W3048475657 cites W208768423 @default.
- W3048475657 cites W2108281900 @default.
- W3048475657 cites W2117029190 @default.
- W3048475657 cites W2135159454 @default.
- W3048475657 cites W2136026605 @default.
- W3048475657 cites W2141436645 @default.
- W3048475657 cites W2148546434 @default.
- W3048475657 cites W2152213080 @default.
- W3048475657 cites W2154745198 @default.
- W3048475657 cites W2336829371 @default.
- W3048475657 cites W2337492846 @default.
- W3048475657 cites W2468306238 @default.
- W3048475657 cites W2531529187 @default.
- W3048475657 cites W2536503303 @default.
- W3048475657 cites W2548933161 @default.
- W3048475657 cites W2566992328 @default.
- W3048475657 cites W2615801135 @default.
- W3048475657 cites W2754699357 @default.
- W3048475657 cites W2784663216 @default.
- W3048475657 cites W2799884346 @default.
- W3048475657 cites W2801848590 @default.
- W3048475657 cites W2804326576 @default.
- W3048475657 cites W2805365360 @default.
- W3048475657 cites W2890990778 @default.
- W3048475657 cites W2902161130 @default.
- W3048475657 cites W2913977146 @default.
- W3048475657 cites W2943725638 @default.
- W3048475657 cites W2944997976 @default.
- W3048475657 cites W2948506592 @default.
- W3048475657 cites W2952403023 @default.
- W3048475657 cites W2954606580 @default.
- W3048475657 cites W3031468808 @default.
- W3048475657 doi "https://doi.org/10.1016/j.pnpbp.2020.110058" @default.
- W3048475657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32791167" @default.
- W3048475657 hasPublicationYear "2021" @default.
- W3048475657 type Work @default.
- W3048475657 sameAs 3048475657 @default.
- W3048475657 citedByCount "19" @default.
- W3048475657 countsByYear W30484756572021 @default.
- W3048475657 countsByYear W30484756572022 @default.
- W3048475657 countsByYear W30484756572023 @default.
- W3048475657 crossrefType "journal-article" @default.
- W3048475657 hasAuthorship W3048475657A5004494698 @default.
- W3048475657 hasAuthorship W3048475657A5004524995 @default.
- W3048475657 hasAuthorship W3048475657A5006999345 @default.
- W3048475657 hasAuthorship W3048475657A5022751868 @default.
- W3048475657 hasAuthorship W3048475657A5065229969 @default.
- W3048475657 hasAuthorship W3048475657A5068819147 @default.
- W3048475657 hasAuthorship W3048475657A5087945074 @default.
- W3048475657 hasAuthorship W3048475657A5088673743 @default.
- W3048475657 hasConcept C101991246 @default.
- W3048475657 hasConcept C143121216 @default.
- W3048475657 hasConcept C151730666 @default.
- W3048475657 hasConcept C15744967 @default.
- W3048475657 hasConcept C169760540 @default.
- W3048475657 hasConcept C2777389121 @default.
- W3048475657 hasConcept C60644358 @default.
- W3048475657 hasConcept C86803240 @default.
- W3048475657 hasConcept C98274493 @default.
- W3048475657 hasConceptScore W3048475657C101991246 @default.
- W3048475657 hasConceptScore W3048475657C143121216 @default.
- W3048475657 hasConceptScore W3048475657C151730666 @default.
- W3048475657 hasConceptScore W3048475657C15744967 @default.
- W3048475657 hasConceptScore W3048475657C169760540 @default.
- W3048475657 hasConceptScore W3048475657C2777389121 @default.
- W3048475657 hasConceptScore W3048475657C60644358 @default.
- W3048475657 hasConceptScore W3048475657C86803240 @default.
- W3048475657 hasConceptScore W3048475657C98274493 @default.
- W3048475657 hasFunder F4320321001 @default.
- W3048475657 hasLocation W30484756571 @default.
- W3048475657 hasOpenAccess W3048475657 @default.
- W3048475657 hasPrimaryLocation W30484756571 @default.
- W3048475657 hasRelatedWork W2063676536 @default.