FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048499543> ?p ?o ?g. }

• W3048499543 abstract "Chromosome fragile sites tend to form gap or break in chromosomes when the cells are exposed to replication stress. Folic acid deprivation in the culture medium induces folate-sensitive rare fragile sites, such as FRAXA which is responsible for the fragile X mental retardation syndrome. Chromosome instability at fragile sites can be evaluated by biomarkers of genomic instability such as frequency of micronuclei (MN). It was aimed to analyse the chromosome content of MN in Fragile X cells during folate deprivation by the MN-fluorescence in situ hybridization (FISH) method. Samples from five Fragile X syndrome patients, diagnosed using cytogenetic and molecular methods, as well as from their parents and five controls were included in the study. Blood samples were cultured in two different culture media (folate-deficient and normal). Results of MN-FISH test were analysed in terms of MN frequency and chromosome content of MN. An accumulation of MN in Fragile X patients, mainly containing T (+) or C (+) MN or T (+) plus C (+) MN in binucleated cells was found. Finally, MN-FISH analysis allowed confirming that the increase in MN frequency is due to a higher sensitivity to chromosome breakage along the X chromosome." @default.
• W3048499543 created "2020-08-18" @default.
• W3048499543 creator A5002390605 @default.
• W3048499543 creator A5019893163 @default.
• W3048499543 creator A5022002024 @default.
• W3048499543 date "2020-01-01" @default.
• W3048499543 modified "2023-09-26" @default.
• W3048499543 title "Analysis of Xq27.3 Fragility Using the Micronucleus-Fluorescence In situ Hybridization Assay" @default.
• W3048499543 cites W1981118438 @default.
• W3048499543 cites W1986804263 @default.
• W3048499543 cites W1992156666 @default.
• W3048499543 cites W1992966555 @default.
• W3048499543 cites W1995561460 @default.
• W3048499543 cites W2014494217 @default.
• W3048499543 cites W2024699988 @default.
• W3048499543 cites W2027600073 @default.
• W3048499543 cites W2037220090 @default.
• W3048499543 cites W2064154744 @default.
• W3048499543 cites W2073466970 @default.
• W3048499543 cites W2100770813 @default.
• W3048499543 cites W2112784018 @default.
• W3048499543 cites W2115704275 @default.
• W3048499543 cites W2125853201 @default.
• W3048499543 cites W2132607882 @default.
• W3048499543 cites W2138713591 @default.
• W3048499543 cites W2141066291 @default.
• W3048499543 cites W2141296384 @default.
• W3048499543 cites W2143457082 @default.
• W3048499543 cites W2146102106 @default.
• W3048499543 cites W2147705840 @default.
• W3048499543 cites W2152825552 @default.
• W3048499543 cites W2156760055 @default.
• W3048499543 cites W2162561014 @default.
• W3048499543 cites W2164955296 @default.
• W3048499543 cites W2170948220 @default.
• W3048499543 cites W2184194630 @default.
• W3048499543 cites W2403486666 @default.
• W3048499543 cites W2766201197 @default.
• W3048499543 cites W2804051470 @default.
• W3048499543 cites W2902990312 @default.
• W3048499543 cites W4230974614 @default.
• W3048499543 cites W4379373823 @default.
• W3048499543 doi "https://doi.org/10.4103/genint.genint_4_20" @default.
• W3048499543 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7585461" @default.
• W3048499543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33110486" @default.
• W3048499543 hasPublicationYear "2020" @default.
• W3048499543 type Work @default.
• W3048499543 sameAs 3048499543 @default.
• W3048499543 citedByCount "1" @default.
• W3048499543 countsByYear W30484995432022 @default.
• W3048499543 crossrefType "journal-article" @default.
• W3048499543 hasAuthorship W3048499543A5002390605 @default.
• W3048499543 hasAuthorship W3048499543A5019893163 @default.
• W3048499543 hasAuthorship W3048499543A5022002024 @default.
• W3048499543 hasBestOaLocation W30484995432 @default.
• W3048499543 hasConcept C104317684 @default.
• W3048499543 hasConcept C105580179 @default.
• W3048499543 hasConcept C126322002 @default.
• W3048499543 hasConcept C140752955 @default.
• W3048499543 hasConcept C143016879 @default.
• W3048499543 hasConcept C153911025 @default.
• W3048499543 hasConcept C2777542201 @default.
• W3048499543 hasConcept C2777630245 @default.
• W3048499543 hasConcept C29730261 @default.
• W3048499543 hasConcept C30481170 @default.
• W3048499543 hasConcept C35158069 @default.
• W3048499543 hasConcept C36681516 @default.
• W3048499543 hasConcept C45080847 @default.
• W3048499543 hasConcept C53226629 @default.
• W3048499543 hasConcept C54355233 @default.
• W3048499543 hasConcept C60449816 @default.
• W3048499543 hasConcept C71924100 @default.
• W3048499543 hasConcept C81439078 @default.
• W3048499543 hasConcept C86803240 @default.
• W3048499543 hasConceptScore W3048499543C104317684 @default.
• W3048499543 hasConceptScore W3048499543C105580179 @default.
• W3048499543 hasConceptScore W3048499543C126322002 @default.
• W3048499543 hasConceptScore W3048499543C140752955 @default.
• W3048499543 hasConceptScore W3048499543C143016879 @default.
• W3048499543 hasConceptScore W3048499543C153911025 @default.
• W3048499543 hasConceptScore W3048499543C2777542201 @default.
• W3048499543 hasConceptScore W3048499543C2777630245 @default.
• W3048499543 hasConceptScore W3048499543C29730261 @default.
• W3048499543 hasConceptScore W3048499543C30481170 @default.
• W3048499543 hasConceptScore W3048499543C35158069 @default.
• W3048499543 hasConceptScore W3048499543C36681516 @default.
• W3048499543 hasConceptScore W3048499543C45080847 @default.
• W3048499543 hasConceptScore W3048499543C53226629 @default.
• W3048499543 hasConceptScore W3048499543C54355233 @default.
• W3048499543 hasConceptScore W3048499543C60449816 @default.
• W3048499543 hasConceptScore W3048499543C71924100 @default.
• W3048499543 hasConceptScore W3048499543C81439078 @default.
• W3048499543 hasConceptScore W3048499543C86803240 @default.
• W3048499543 hasLocation W30484995431 @default.
• W3048499543 hasLocation W30484995432 @default.
• W3048499543 hasLocation W30484995433 @default.
• W3048499543 hasOpenAccess W3048499543 @default.
• W3048499543 hasPrimaryLocation W30484995431 @default.
• W3048499543 hasRelatedWork W1989442796 @default.
• W3048499543 hasRelatedWork W2068266928 @default.

• next