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- W3048572398 abstract "Although T cells are considered as the central component in immune-mediated diseases, supportive evidence has demonstrated that B cells also contribute to the progression of these diseases. B cells are divided into various subsets according to their secreted cytokines. Different B cell subsets play diverse roles in immune-mediated dermatoses. Regulatory B cells (Bregs) are defined functionally by their ability to secrete IL-10, which has been revealed to contribute to immunological tolerance. Drugs that deplete B cells, such as rituximab, are now used for the treatment of several immune-mediated dermatoses. In this review, we present and discuss the current knowledge on the roles of B cells in several immune-mediate dermatoses including psoriasis, pemphigus, bullous pemphigoid, and dermatomyositis, atopic dermatitis." @default.
- W3048572398 created "2020-08-18" @default.
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- W3048572398 date "2020-10-01" @default.
- W3048572398 modified "2023-10-16" @default.
- W3048572398 title "Role of B cells in immune-mediated dermatoses" @default.
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- W3048572398 doi "https://doi.org/10.1016/j.molimm.2020.07.016" @default.
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