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- W3048595992 abstract "Introduction Autophagy is an evolutionarily conserved cellular clearance process, by which cytosolic components are delivered to autolysosomes for breakdown and recycling to maintain cellular homeostasis. During the past decades, autophagy has been found to be tightly implicated in various physiological and pathological progresses. Unraveling the regulatory mechanisms of the autophagy process will contribute to the development of emerging autophagy-targeting strategies for the treatment of various diseases. Recently, the rapid development of proteomics approaches has enabled the use of large-scale unbiased strategies to unravel autophagy machinery.Areas covered In this review, we will highlight the recent contributions of proteomics strategies in clarifying the autophagy machinery, with an emphasis on the three different types of autophagy (namely macroautophagy, microautophagy, and chaperone-mediated autophagy). We will also discuss the emerging role of proteomics approaches in investigating the mechanism of the autophagy-based unconventional secretory pathway (secretory autophagy).Expert opinion Proteomics has provided an effective strategy for the comprehensive analysis of the autophagy process, which will broaden our understanding of autophagy machinery, and holds great promise for developing clinical therapies targeting autophagy." @default.
- W3048595992 created "2020-08-18" @default.
- W3048595992 creator A5016414843 @default.
- W3048595992 creator A5020455747 @default.
- W3048595992 creator A5021333880 @default.
- W3048595992 creator A5031792222 @default.
- W3048595992 creator A5033851605 @default.
- W3048595992 creator A5040250751 @default.
- W3048595992 creator A5052282683 @default.
- W3048595992 date "2020-08-02" @default.
- W3048595992 modified "2023-10-15" @default.
- W3048595992 title "Recent advances in autophagic machinery: a proteomic perspective" @default.
- W3048595992 cites W1819972003 @default.
- W3048595992 cites W1860864010 @default.
- W3048595992 cites W1964328150 @default.
- W3048595992 cites W1964643816 @default.
- W3048595992 cites W1966347583 @default.
- W3048595992 cites W1970637701 @default.
- W3048595992 cites W1980496079 @default.
- W3048595992 cites W1981153918 @default.
- W3048595992 cites W1992532731 @default.
- W3048595992 cites W1996068251 @default.
- W3048595992 cites W1996152690 @default.
- W3048595992 cites W1996625702 @default.
- W3048595992 cites W1997365035 @default.
- W3048595992 cites W2002174575 @default.
- W3048595992 cites W2004254720 @default.
- W3048595992 cites W2009484275 @default.
- W3048595992 cites W2021238335 @default.
- W3048595992 cites W2021919397 @default.
- W3048595992 cites W2025205297 @default.
- W3048595992 cites W2032186831 @default.
- W3048595992 cites W2032700869 @default.
- W3048595992 cites W2033191689 @default.
- W3048595992 cites W2041686750 @default.
- W3048595992 cites W2042840948 @default.
- W3048595992 cites W2043896568 @default.
- W3048595992 cites W2045373134 @default.
- W3048595992 cites W2049953895 @default.
- W3048595992 cites W2059162472 @default.
- W3048595992 cites W2071466153 @default.
- W3048595992 cites W2073691055 @default.
- W3048595992 cites W2077757969 @default.
- W3048595992 cites W2079843936 @default.
- W3048595992 cites W2080689345 @default.
- W3048595992 cites W2084693908 @default.
- W3048595992 cites W2085470568 @default.
- W3048595992 cites W2096065711 @default.
- W3048595992 cites W2097830998 @default.
- W3048595992 cites W2098969660 @default.
- W3048595992 cites W2103230459 @default.
- W3048595992 cites W2107153295 @default.
- W3048595992 cites W2109070574 @default.
- W3048595992 cites W2111362374 @default.
- W3048595992 cites W2117454877 @default.
- W3048595992 cites W2127063807 @default.
- W3048595992 cites W2132763961 @default.
- W3048595992 cites W2139446098 @default.
- W3048595992 cites W2149200223 @default.
- W3048595992 cites W2161132697 @default.
- W3048595992 cites W2165218453 @default.
- W3048595992 cites W2167270153 @default.
- W3048595992 cites W2168326939 @default.
- W3048595992 cites W2171213306 @default.
- W3048595992 cites W2181193101 @default.
- W3048595992 cites W2262858406 @default.
- W3048595992 cites W2267713729 @default.
- W3048595992 cites W2271324282 @default.
- W3048595992 cites W2273029159 @default.
- W3048595992 cites W2295351013 @default.
- W3048595992 cites W2318418872 @default.
- W3048595992 cites W2335768256 @default.
- W3048595992 cites W2436491355 @default.
- W3048595992 cites W2465357381 @default.
- W3048595992 cites W2468305494 @default.
- W3048595992 cites W2501231940 @default.
- W3048595992 cites W2509808353 @default.
- W3048595992 cites W2551198602 @default.
- W3048595992 cites W2560000662 @default.
- W3048595992 cites W2563034400 @default.
- W3048595992 cites W2570675177 @default.
- W3048595992 cites W2584220830 @default.
- W3048595992 cites W2589643982 @default.
- W3048595992 cites W2597177247 @default.
- W3048595992 cites W2604133228 @default.
- W3048595992 cites W2605825818 @default.
- W3048595992 cites W2609461401 @default.
- W3048595992 cites W2616561032 @default.
- W3048595992 cites W2617230702 @default.
- W3048595992 cites W2701590668 @default.
- W3048595992 cites W2735873011 @default.
- W3048595992 cites W2739444720 @default.
- W3048595992 cites W2740618823 @default.
- W3048595992 cites W2744123648 @default.
- W3048595992 cites W2745047586 @default.
- W3048595992 cites W2749549459 @default.
- W3048595992 cites W2755721896 @default.
- W3048595992 cites W2758797028 @default.