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- W3048612424 abstract "Covering: up to 2020Treatment resistance and drug-induced refractory malignancies pose significant challenges for current chemotherapy drugs. There have been increasing research efforts aimed at developing novel chemotherapeutics, especially from natural products and related derivatives. Natural cytotoxic peptides, an emerging source of chemotherapeutics, have exhibited the advantage of overcoming drug resistance and displayed broad-spectrum antitumor activities in the clinic. This highlight examines the increasingly popular cytotoxic peptides from isolated natural products. In-depth review of several peptides provides examples for how this novel strategy can lead to the improved anti-tumor effects. The mechanisms and current application of representative natural cytotoxic peptides (NCPs) have also been discussed, with a particular focus on future directions for interdisciplinary research." @default.
- W3048612424 created "2020-08-18" @default.
- W3048612424 creator A5002855077 @default.
- W3048612424 creator A5003123045 @default.
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- W3048612424 creator A5056344408 @default.
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- W3048612424 creator A5063575243 @default.
- W3048612424 creator A5075830148 @default.
- W3048612424 creator A5090176999 @default.
- W3048612424 date "2021-01-01" @default.
- W3048612424 modified "2023-09-29" @default.
- W3048612424 title "Cytotoxic and antitumor peptides as novel chemotherapeutics" @default.
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