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- W3048624891 abstract "Tissue engineering (TE) aims to regenerate critical size defects, which cannot heal naturally, by using highly porous matrices called TE scaffolds made of biocompatible and biodegradable biomaterials. There are various manufacturing techniques commonly used to fabricate TE scaffolds. However, in most cases, they do not provide materials with a highly interconnected pore design. Thus, emulsion templating is a promising and convenient route for the fabrication of matrices with up to 99% porosity and high interconnectivity. These matrices have been used for various application areas for decades. Although this polymer structuring technique is older than TE itself, the use of polymerised internal phase emulsions (PolyHIPEs) in TE is relatively new compared to other scaffold manufacturing techniques. It is likely because it requires multidisciplinary background including materials science, chemistry and TE although producing emulsion templated scaffolds is practically simple. To date, a number of excellent reviews on emulsion templating have been published by the pioneers of this field in order to explain the chemistry behind this technique and potential areas of use of the emulsion templated structures. This particular review focusses on the key points of how emulsion templated scaffolds can be fabricated for different TE applications. Accordingly, we first explain the basics of emulsion templating and characteristics of PolyHIPE scaffolds. Then, we discuss the role of each ingredient in the emulsion and the impact of the compositional changes and process conditions on the characteristics of PolyHIPEs. Afterwards, current fabrication methods of biocompatible PolyHIPE scaffolds and polymerisation routes are detailed, and the functionalisation strategies that can be used to improve the biological activity of PolyHIPE scaffolds are discussed. Finally, the applications of PolyHIPEs on soft and hard TE as well as in vitro models and drug delivery in the literature are summarised." @default.
- W3048624891 created "2020-08-18" @default.
- W3048624891 creator A5020388446 @default.
- W3048624891 creator A5087716394 @default.
- W3048624891 date "2020-08-12" @default.
- W3048624891 modified "2023-10-15" @default.
- W3048624891 title "Basic Principles of Emulsion Templating and Its Use as an Emerging Manufacturing Method of Tissue Engineering Scaffolds" @default.
- W3048624891 cites W1481373378 @default.
- W3048624891 cites W1493967000 @default.
- W3048624891 cites W1494283264 @default.
- W3048624891 cites W1526408795 @default.
- W3048624891 cites W1544133347 @default.
- W3048624891 cites W1556974933 @default.
- W3048624891 cites W1783550762 @default.
- W3048624891 cites W1875687721 @default.
- W3048624891 cites W1891300543 @default.
- W3048624891 cites W1902391461 @default.
- W3048624891 cites W1954225767 @default.
- W3048624891 cites W1964674717 @default.
- W3048624891 cites W1965595815 @default.
- W3048624891 cites W1970190501 @default.
- W3048624891 cites W1970436035 @default.
- W3048624891 cites W1971839302 @default.
- W3048624891 cites W1972728648 @default.
- W3048624891 cites W1974679617 @default.
- W3048624891 cites W1974816528 @default.
- W3048624891 cites W1975833234 @default.
- W3048624891 cites W1976655238 @default.
- W3048624891 cites W1977042955 @default.
- W3048624891 cites W1980237153 @default.
- W3048624891 cites W1980573164 @default.
- W3048624891 cites W1984537418 @default.
- W3048624891 cites W1984685797 @default.
- W3048624891 cites W1985558016 @default.
- W3048624891 cites W1985813526 @default.
- W3048624891 cites W1986492406 @default.
- W3048624891 cites W1987649713 @default.
- W3048624891 cites W1990847801 @default.
- W3048624891 cites W1993418575 @default.
- W3048624891 cites W1994560822 @default.
- W3048624891 cites W1994732669 @default.
- W3048624891 cites W1998543096 @default.
- W3048624891 cites W1998663567 @default.
- W3048624891 cites W2001380203 @default.
- W3048624891 cites W2002022364 @default.
- W3048624891 cites W2008315398 @default.
- W3048624891 cites W2009612546 @default.
- W3048624891 cites W2010143056 @default.
- W3048624891 cites W2011364980 @default.
- W3048624891 cites W2011571470 @default.
- W3048624891 cites W2012924439 @default.
- W3048624891 cites W2013570431 @default.
- W3048624891 cites W2014785305 @default.
- W3048624891 cites W2015871985 @default.
- W3048624891 cites W2017023732 @default.
- W3048624891 cites W2017375863 @default.
- W3048624891 cites W2019168090 @default.
- W3048624891 cites W2022097468 @default.
- W3048624891 cites W2022173006 @default.
- W3048624891 cites W2023379929 @default.
- W3048624891 cites W2025757488 @default.
- W3048624891 cites W2025858878 @default.
- W3048624891 cites W2026480614 @default.
- W3048624891 cites W2028919654 @default.
- W3048624891 cites W2029147148 @default.
- W3048624891 cites W2029643095 @default.
- W3048624891 cites W2029737011 @default.
- W3048624891 cites W2030819965 @default.
- W3048624891 cites W2036993983 @default.
- W3048624891 cites W2038517898 @default.
- W3048624891 cites W2040099152 @default.
- W3048624891 cites W2043307989 @default.
- W3048624891 cites W2045470060 @default.
- W3048624891 cites W2045717301 @default.
- W3048624891 cites W2046061689 @default.
- W3048624891 cites W2048476453 @default.
- W3048624891 cites W2048528478 @default.
- W3048624891 cites W2048667171 @default.
- W3048624891 cites W2049877242 @default.
- W3048624891 cites W2051063170 @default.
- W3048624891 cites W2052753036 @default.
- W3048624891 cites W2054813765 @default.
- W3048624891 cites W2056100254 @default.
- W3048624891 cites W2056115605 @default.
- W3048624891 cites W2056604592 @default.
- W3048624891 cites W2060257015 @default.
- W3048624891 cites W2061167709 @default.
- W3048624891 cites W2062224667 @default.
- W3048624891 cites W2063574167 @default.
- W3048624891 cites W2063884667 @default.
- W3048624891 cites W2064133567 @default.
- W3048624891 cites W2071662902 @default.
- W3048624891 cites W2071968414 @default.
- W3048624891 cites W2074096615 @default.
- W3048624891 cites W2074255287 @default.
- W3048624891 cites W2074525088 @default.
- W3048624891 cites W2074865082 @default.
- W3048624891 cites W2078826425 @default.
- W3048624891 cites W2081134366 @default.
- W3048624891 cites W2081672582 @default.