FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048634369> ?p ?o ?g. }

• W3048634369 endingPage "257.e3" @default.
• W3048634369 startingPage "247" @default.
• W3048634369 abstract "Objective To ascertain the descriptive epidemiology of infant botulism, the flaccid paralysis that results when neurotoxigenic Clostridium species produce botulinum toxin (BoNT) in the infant colon, in its first 40 years following initial recognition in California in 1976. Study design Cases were defined by laboratory identification of BoNT and/or neurotoxigenic Clostridium species in patients' feces. Parents were interviewed using a structured questionnaire. Descriptive epidemiologic characteristics were compared between 1976-1996 and 1997-2016. Results From 1976-2016, 1345 cases of infant botulism occurred in 45 of 58 California counties (6.5 cases/100 000 live-births/year) caused by BoNT types A, B, Ba, Bf, and F; 88% of cases were ≤6 months of age and 51% were female. Cases were white (84.2%), Asian (8.9%), other races (3.8%), and African American (2.8%); 29.4% of cases were Hispanic. More than 99% of cases were hospitalized. Case occurrence peaked in summer-fall. Of 8 designated geographic regions, the Central Coast counties had 3 times the statewide incidence in both 20-year time periods. Breast-fed patients (83%) were more than twice as old at onset as formula-fed patients (median, 4.4 vs 1.7 months, respectively; P < .001). BoNT/A cases were older at onset than BoNT/B cases (median, 3.8 vs 2.9 months, respectively; P < .001). Conclusions Comprehensive continuous surveillance of infant botulism for 40 years in a large, diversely populated state identified fundamental epidemiologic characteristics of this uncommon illness. Unusual features included greater than 99% case hospitalization, absence of male preponderance, and a distinctive age distribution. To ascertain the descriptive epidemiology of infant botulism, the flaccid paralysis that results when neurotoxigenic Clostridium species produce botulinum toxin (BoNT) in the infant colon, in its first 40 years following initial recognition in California in 1976. Cases were defined by laboratory identification of BoNT and/or neurotoxigenic Clostridium species in patients' feces. Parents were interviewed using a structured questionnaire. Descriptive epidemiologic characteristics were compared between 1976-1996 and 1997-2016. From 1976-2016, 1345 cases of infant botulism occurred in 45 of 58 California counties (6.5 cases/100 000 live-births/year) caused by BoNT types A, B, Ba, Bf, and F; 88% of cases were ≤6 months of age and 51% were female. Cases were white (84.2%), Asian (8.9%), other races (3.8%), and African American (2.8%); 29.4% of cases were Hispanic. More than 99% of cases were hospitalized. Case occurrence peaked in summer-fall. Of 8 designated geographic regions, the Central Coast counties had 3 times the statewide incidence in both 20-year time periods. Breast-fed patients (83%) were more than twice as old at onset as formula-fed patients (median, 4.4 vs 1.7 months, respectively; P < .001). BoNT/A cases were older at onset than BoNT/B cases (median, 3.8 vs 2.9 months, respectively; P < .001). Comprehensive continuous surveillance of infant botulism for 40 years in a large, diversely populated state identified fundamental epidemiologic characteristics of this uncommon illness. Unusual features included greater than 99% case hospitalization, absence of male preponderance, and a distinctive age distribution." @default.
• W3048634369 created "2020-08-18" @default.
• W3048634369 creator A5002621961 @default.
• W3048634369 creator A5004936193 @default.
• W3048634369 creator A5011230261 @default.
• W3048634369 creator A5035415175 @default.
• W3048634369 creator A5040828493 @default.
• W3048634369 creator A5067785586 @default.
• W3048634369 date "2020-12-01" @default.
• W3048634369 modified "2023-10-03" @default.
• W3048634369 title "Descriptive Epidemiology of Infant Botulism in California: The First 40 Years" @default.
• W3048634369 cites W1527364761 @default.
• W3048634369 cites W1550962096 @default.
• W3048634369 cites W1594755663 @default.
• W3048634369 cites W1965360904 @default.
• W3048634369 cites W1974559413 @default.
• W3048634369 cites W1985297128 @default.
• W3048634369 cites W1995303174 @default.
• W3048634369 cites W1997336833 @default.
• W3048634369 cites W2002595702 @default.
• W3048634369 cites W2010512455 @default.
• W3048634369 cites W2028669247 @default.
• W3048634369 cites W2042906668 @default.
• W3048634369 cites W2054832451 @default.
• W3048634369 cites W2063330137 @default.
• W3048634369 cites W2070084762 @default.
• W3048634369 cites W2071881166 @default.
• W3048634369 cites W2077082095 @default.
• W3048634369 cites W2080475115 @default.
• W3048634369 cites W2083978706 @default.
• W3048634369 cites W2088848295 @default.
• W3048634369 cites W2095412370 @default.
• W3048634369 cites W2096738649 @default.
• W3048634369 cites W2097613547 @default.
• W3048634369 cites W2097646595 @default.
• W3048634369 cites W2101211619 @default.
• W3048634369 cites W2106861685 @default.
• W3048634369 cites W2107671787 @default.
• W3048634369 cites W2113439238 @default.
• W3048634369 cites W2114014609 @default.
• W3048634369 cites W2116995403 @default.
• W3048634369 cites W2126213235 @default.
• W3048634369 cites W2131949225 @default.
• W3048634369 cites W2136754601 @default.
• W3048634369 cites W2153643562 @default.
• W3048634369 cites W2156332660 @default.
• W3048634369 cites W2158383741 @default.
• W3048634369 cites W2162709972 @default.
• W3048634369 cites W2162806041 @default.
• W3048634369 cites W2225433666 @default.
• W3048634369 cites W2266660463 @default.
• W3048634369 cites W2285065014 @default.
• W3048634369 cites W2295237082 @default.
• W3048634369 cites W2301546790 @default.
• W3048634369 cites W2314219369 @default.
• W3048634369 cites W2319857288 @default.
• W3048634369 cites W2330050869 @default.
• W3048634369 cites W2337450480 @default.
• W3048634369 cites W2410504821 @default.
• W3048634369 cites W2518536270 @default.
• W3048634369 cites W2558189339 @default.
• W3048634369 cites W2559252072 @default.
• W3048634369 cites W2559424112 @default.
• W3048634369 cites W2562839140 @default.
• W3048634369 cites W2592067062 @default.
• W3048634369 cites W2740139987 @default.
• W3048634369 cites W2773894773 @default.
• W3048634369 cites W2778849518 @default.
• W3048634369 cites W2791119554 @default.
• W3048634369 cites W2791745812 @default.
• W3048634369 cites W2792808282 @default.
• W3048634369 cites W2800834686 @default.
• W3048634369 cites W2802948746 @default.
• W3048634369 cites W2997767557 @default.
• W3048634369 cites W3040645670 @default.
• W3048634369 cites W4210859727 @default.
• W3048634369 cites W4241019103 @default.
• W3048634369 doi "https://doi.org/10.1016/j.jpeds.2020.08.013" @default.
• W3048634369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32800814" @default.
• W3048634369 hasPublicationYear "2020" @default.
• W3048634369 type Work @default.
• W3048634369 sameAs 3048634369 @default.
• W3048634369 citedByCount "11" @default.
• W3048634369 countsByYear W30486343692020 @default.
• W3048634369 countsByYear W30486343692021 @default.
• W3048634369 countsByYear W30486343692022 @default.
• W3048634369 countsByYear W30486343692023 @default.
• W3048634369 crossrefType "journal-article" @default.
• W3048634369 hasAuthorship W3048634369A5002621961 @default.
• W3048634369 hasAuthorship W3048634369A5004936193 @default.
• W3048634369 hasAuthorship W3048634369A5011230261 @default.
• W3048634369 hasAuthorship W3048634369A5035415175 @default.
• W3048634369 hasAuthorship W3048634369A5040828493 @default.
• W3048634369 hasAuthorship W3048634369A5067785586 @default.
• W3048634369 hasConcept C107130276 @default.
• W3048634369 hasConcept C120665830 @default.
• W3048634369 hasConcept C121332964 @default.
• W3048634369 hasConcept C126322002 @default.

• next