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- W3048645955 abstract "Abstract Introduction Tamoxifen is a non-steroidal anti-oestrogen that acts as an antagonist in breast tissue, neurosensory retina, and retinal pigment epithelium (RPE). The reported incidence of its ocular effects varies between 0.9% and 11%. Methods Case series. Multimodal image studies were used to evaluate three female patients who were receiving tamoxifen for breast cancer for the purpose of monitoring and determining whether there are changes after discontinuation of treatment. Results All three patients showed signs of crystalline retinopathy using spectral domain optical coherence tomography (SD-OCT) during follow-up. Conclusion The follow-up using multimodal imaging studies allowed evaluating the progression of the changes, providing a prognostic assessment. The findings found (visual acuity and multimodal imaging) confirmed the results of previous studies, indicating that, at a certain level of toxicity, the damage was irreversible." @default.
- W3048645955 created "2020-08-18" @default.
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- W3048645955 date "2020-10-01" @default.
- W3048645955 modified "2023-10-18" @default.
- W3048645955 title "Tamoxifen retinal toxicity. Monitoring by multimodal imaging study" @default.
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- W3048645955 doi "https://doi.org/10.1016/j.oftale.2020.05.022" @default.
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