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- W3048651437 abstract "A seven years old sample of cefaclor stored in room conditions, as a solid, has been analyzed by using high performence liquid chromatography/electrospray ionization-mass spectrometry. As a result of the sample degradation process, two diastereomers of Impurity E have been found to have formed. It is reasonable to assume that the diastereomers are formed due to the isomerization of C6 carbon atom. They have almost identical fragmentation patterns in both positive and negative ion mode. On the other hand, the diastereomers have different efficiencies of formation of dimer ions, under ESI conditions, especially in negative ion mode." @default.
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- W3048651437 date "2020-10-01" @default.
- W3048651437 modified "2023-09-23" @default.
- W3048651437 title "HPLC/ESI-MS identification of diastereomers of Impurity E – Degradation products of cefaclor" @default.
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- W3048651437 doi "https://doi.org/10.1016/j.jpba.2020.113533" @default.
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