Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048653102> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W3048653102 abstract "Supplementation of fresh frozen plasma immediately after cardiopulmonary bypass is an effective method to enhance clotting ability as coagulation factors are consumed in the extracorporeal circuit during cardiopulmonary bypass. On the other hand, the anticoagulation factors in fresh frozen plasma can also deter the clotting ability. This study investigated the effect of fresh frozen plasma administration on the comprehensive clotting ability following cardiopulmonary bypass.This prospective observational study included 22 patients scheduled for cardiac surgery. Clotting times and maximum clot firmness were evaluated using the types of rotational thromboelastometry, intrinsic rotational thromboelastometry, and heparinase thromboelastography preoperatively, immediately after cardiopulmonary bypass, and 1 hour after cardiopulmonary bypass. Activated clotting time, antithrombin activity, and heparin concentration were also measured at these time-points.Antithrombin activity (62.9 ± 7.2% vs. 51.1 ± 7.4%, p < 0.0001) and activated clotting time (132.6 ± 9.6% vs. 120.0 ± 9.0%, p < 0.001) were significantly higher 1 hour after cardiopulmonary bypass compared to measurements taken immediately after cardiopulmonary bypass. Heparin concentration 1 hour after cardiopulmonary bypass was significantly decreased compared to that immediately after cardiopulmonary bypass. On the other hand, maximum clot firmness determined via intrinsic rotational thromboelastometry was significantly greater 1 hour after cardiopulmonary bypass (53.8 ± 4.8 mm) than that immediately after cardiopulmonary bypass (49.5 ± 4.8 mm). Clotting time determined via intrinsic rotational thromboelastometry and heparinase thromboelastography was also significantly shorter 1 hour after cardiopulmonary bypass than that immediately after cardiopulmonary bypass.Fresh frozen plasma administration increased antithrombin activity and caused activated clotting time prolongation, but then increased clotting ability. Thus, testing by rotational thromboelastometry after cardiopulmonary bypass could be valuable in the detection of comprehensive clotting ability." @default.
- W3048653102 created "2020-08-18" @default.
- W3048653102 creator A5009803039 @default.
- W3048653102 creator A5069602580 @default.
- W3048653102 creator A5043188465 @default.
- W3048653102 date "2020-08-12" @default.
- W3048653102 modified "2023-09-23" @default.
- W3048653102 title "Effect of antithrombin in fresh frozen plasma on hemostasis after cardiopulmonary bypass surgery" @default.
- W3048653102 cites W1496302158 @default.
- W3048653102 cites W1842328209 @default.
- W3048653102 cites W1956228597 @default.
- W3048653102 cites W1972004375 @default.
- W3048653102 cites W1989560973 @default.
- W3048653102 cites W2011012256 @default.
- W3048653102 cites W2030645894 @default.
- W3048653102 cites W2035823633 @default.
- W3048653102 cites W2063812212 @default.
- W3048653102 cites W2102015392 @default.
- W3048653102 cites W2102770802 @default.
- W3048653102 cites W2130996231 @default.
- W3048653102 cites W2154074900 @default.
- W3048653102 cites W816451784 @default.
- W3048653102 doi "https://doi.org/10.1177/0267659120948435" @default.
- W3048653102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32781884" @default.
- W3048653102 hasPublicationYear "2020" @default.
- W3048653102 type Work @default.
- W3048653102 sameAs 3048653102 @default.
- W3048653102 citedByCount "0" @default.
- W3048653102 crossrefType "journal-article" @default.
- W3048653102 hasAuthorship W3048653102A5009803039 @default.
- W3048653102 hasAuthorship W3048653102A5043188465 @default.
- W3048653102 hasAuthorship W3048653102A5069602580 @default.
- W3048653102 hasConcept C126322002 @default.
- W3048653102 hasConcept C164705383 @default.
- W3048653102 hasConcept C26809991 @default.
- W3048653102 hasConcept C2777557582 @default.
- W3048653102 hasConcept C2777664302 @default.
- W3048653102 hasConcept C2777987278 @default.
- W3048653102 hasConcept C2778382381 @default.
- W3048653102 hasConcept C2778789114 @default.
- W3048653102 hasConcept C2778881276 @default.
- W3048653102 hasConcept C2779026020 @default.
- W3048653102 hasConcept C2992139802 @default.
- W3048653102 hasConcept C2994232697 @default.
- W3048653102 hasConcept C42219234 @default.
- W3048653102 hasConcept C66112548 @default.
- W3048653102 hasConcept C71924100 @default.
- W3048653102 hasConcept C77171857 @default.
- W3048653102 hasConcept C89560881 @default.
- W3048653102 hasConceptScore W3048653102C126322002 @default.
- W3048653102 hasConceptScore W3048653102C164705383 @default.
- W3048653102 hasConceptScore W3048653102C26809991 @default.
- W3048653102 hasConceptScore W3048653102C2777557582 @default.
- W3048653102 hasConceptScore W3048653102C2777664302 @default.
- W3048653102 hasConceptScore W3048653102C2777987278 @default.
- W3048653102 hasConceptScore W3048653102C2778382381 @default.
- W3048653102 hasConceptScore W3048653102C2778789114 @default.
- W3048653102 hasConceptScore W3048653102C2778881276 @default.
- W3048653102 hasConceptScore W3048653102C2779026020 @default.
- W3048653102 hasConceptScore W3048653102C2992139802 @default.
- W3048653102 hasConceptScore W3048653102C2994232697 @default.
- W3048653102 hasConceptScore W3048653102C42219234 @default.
- W3048653102 hasConceptScore W3048653102C66112548 @default.
- W3048653102 hasConceptScore W3048653102C71924100 @default.
- W3048653102 hasConceptScore W3048653102C77171857 @default.
- W3048653102 hasConceptScore W3048653102C89560881 @default.
- W3048653102 hasLocation W30486531021 @default.
- W3048653102 hasLocation W30486531022 @default.
- W3048653102 hasOpenAccess W3048653102 @default.
- W3048653102 hasPrimaryLocation W30486531021 @default.
- W3048653102 hasRelatedWork W10798469 @default.
- W3048653102 hasRelatedWork W11456702 @default.
- W3048653102 hasRelatedWork W14769177 @default.
- W3048653102 hasRelatedWork W16087267 @default.
- W3048653102 hasRelatedWork W4620020 @default.
- W3048653102 hasRelatedWork W4916848 @default.
- W3048653102 hasRelatedWork W5435030 @default.
- W3048653102 hasRelatedWork W7788743 @default.
- W3048653102 hasRelatedWork W8401236 @default.
- W3048653102 hasRelatedWork W14769159 @default.
- W3048653102 isParatext "false" @default.
- W3048653102 isRetracted "false" @default.
- W3048653102 magId "3048653102" @default.
- W3048653102 workType "article" @default.