Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048669276> ?p ?o ?g. }
- W3048669276 endingPage "102688" @default.
- W3048669276 startingPage "102688" @default.
- W3048669276 abstract "Climate change represents a significant environmental challenge to human welfare. One of many negative impacts may be on animal reproduction. Elevated ambient temperature unfavourably influences reproductive processes in mammals. High temperature can affect reproductive processes such as follicle development and may alter follicular fluid concentrations of amino acids, fatty acids, minerals, enzymes, antioxidants defence and growth factors. These impacts may lead to inferior oocyte competence and abnormal granulosa cell (GCs) function. Mammalian oocytes are enclosed by GCs that secret hormones and signalling molecules to promote oocyte competence. GCs are essential for proper follicular development, oocyte maturation, ovulation, and luteinization. Many environmental stressors, including thermal stress, affect GC function and alter oocyte development and growth. Several studies documented a link between elevated ambient temperature and increased generation of cellular reactive oxygen species (ROS). ROS can damage DNA, reduce cell proliferation, and induce apoptosis in GCs, thus altering oocyte development. Additionally, thermal stress induces upregulation of thermal shock proteins, such as HSP70 and HSP90. This review provides an update on the influence of thermal stress on GCs of mammals. Discussions include impacts to steroidogenesis (estradiol and progesterone), proliferation and cell cycle transition, apoptosis, oxidative stress (ROS), antioxidants related genes, heat shock proteins (HSPs) and endoplasmic reticulum responses." @default.
- W3048669276 created "2020-08-18" @default.
- W3048669276 creator A5020387919 @default.
- W3048669276 creator A5061254569 @default.
- W3048669276 creator A5061392895 @default.
- W3048669276 creator A5069506329 @default.
- W3048669276 creator A5070277236 @default.
- W3048669276 date "2020-08-01" @default.
- W3048669276 modified "2023-10-06" @default.
- W3048669276 title "Cellular and functional adaptation to thermal stress in ovarian granulosa cells in mammals" @default.
- W3048669276 cites W1008398044 @default.
- W3048669276 cites W1521908242 @default.
- W3048669276 cites W1563889499 @default.
- W3048669276 cites W1779678074 @default.
- W3048669276 cites W1964776244 @default.
- W3048669276 cites W1967487924 @default.
- W3048669276 cites W1974903260 @default.
- W3048669276 cites W1980749183 @default.
- W3048669276 cites W1982468459 @default.
- W3048669276 cites W1983396423 @default.
- W3048669276 cites W1983687193 @default.
- W3048669276 cites W1983740277 @default.
- W3048669276 cites W1989391398 @default.
- W3048669276 cites W1998682109 @default.
- W3048669276 cites W2001072489 @default.
- W3048669276 cites W2001399725 @default.
- W3048669276 cites W2003801319 @default.
- W3048669276 cites W2007866262 @default.
- W3048669276 cites W2013103342 @default.
- W3048669276 cites W2013846770 @default.
- W3048669276 cites W2019470807 @default.
- W3048669276 cites W2025769913 @default.
- W3048669276 cites W2026336054 @default.
- W3048669276 cites W2036845348 @default.
- W3048669276 cites W2037030746 @default.
- W3048669276 cites W2049389608 @default.
- W3048669276 cites W2053350368 @default.
- W3048669276 cites W2060950890 @default.
- W3048669276 cites W2065504621 @default.
- W3048669276 cites W2070610945 @default.
- W3048669276 cites W2079744815 @default.
- W3048669276 cites W2085707821 @default.
- W3048669276 cites W2092913408 @default.
- W3048669276 cites W2095503516 @default.
- W3048669276 cites W2099365534 @default.
- W3048669276 cites W2103492539 @default.
- W3048669276 cites W2109162211 @default.
- W3048669276 cites W2109874420 @default.
- W3048669276 cites W2126657029 @default.
- W3048669276 cites W2133143602 @default.
- W3048669276 cites W2133237498 @default.
- W3048669276 cites W2147924866 @default.
- W3048669276 cites W2157505479 @default.
- W3048669276 cites W2160270445 @default.
- W3048669276 cites W2161604602 @default.
- W3048669276 cites W2163411496 @default.
- W3048669276 cites W2163428037 @default.
- W3048669276 cites W2168601768 @default.
- W3048669276 cites W2169894769 @default.
- W3048669276 cites W2175584767 @default.
- W3048669276 cites W2205689500 @default.
- W3048669276 cites W2253261722 @default.
- W3048669276 cites W2265677216 @default.
- W3048669276 cites W2398251883 @default.
- W3048669276 cites W2412530533 @default.
- W3048669276 cites W2485662396 @default.
- W3048669276 cites W2513790992 @default.
- W3048669276 cites W2524522112 @default.
- W3048669276 cites W2562345382 @default.
- W3048669276 cites W2584534538 @default.
- W3048669276 cites W2606824156 @default.
- W3048669276 cites W2783020596 @default.
- W3048669276 cites W2791133952 @default.
- W3048669276 cites W2794290318 @default.
- W3048669276 cites W2799544192 @default.
- W3048669276 cites W2803469527 @default.
- W3048669276 cites W2809897870 @default.
- W3048669276 cites W2810630902 @default.
- W3048669276 cites W2883480477 @default.
- W3048669276 cites W2883960619 @default.
- W3048669276 cites W2898030745 @default.
- W3048669276 cites W2905389578 @default.
- W3048669276 cites W2922504308 @default.
- W3048669276 cites W2925411398 @default.
- W3048669276 cites W2954380600 @default.
- W3048669276 cites W2968730769 @default.
- W3048669276 cites W2990215885 @default.
- W3048669276 cites W3000091579 @default.
- W3048669276 cites W3003695059 @default.
- W3048669276 cites W3010749874 @default.
- W3048669276 cites W3016734920 @default.
- W3048669276 doi "https://doi.org/10.1016/j.jtherbio.2020.102688" @default.
- W3048669276 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32888576" @default.
- W3048669276 hasPublicationYear "2020" @default.
- W3048669276 type Work @default.
- W3048669276 sameAs 3048669276 @default.
- W3048669276 citedByCount "14" @default.
- W3048669276 countsByYear W30486692762021 @default.