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• W3048700906 abstract "Abstract Background: The incidence of colorectal cancer is persistently higher in Black/African Americans than other races in the United States. It is less clear whether Black/African Americans are at higher risk for colonic precancerous polyps, which represent an earlier stage in colorectal adenoma-carcinoma progression. Methods: A retrospective chart review was performed on initial average-risk screening colonoscopies on patients (age 45-75 years) during 2012 at 3 institutions. Multivariable logistic regression models were used to examine the relationship between potential risk factors and the detection of precancerous polyps. Results: Of the 2,225 initial screening colonoscopies, 1,495 (67.2%) were performed on Black/African Americans and 566 (25.4%) on Caucasian non-Hispanic patients. The mean age of initial colonoscopies was 57.1 y and 56.0 y for Black and Caucasian patients, respectively. Male patients represented 32.0% and 42.8% of the Black and Caucasian patients, respectively. Obese patients represented 41.4% and 31% of Black and Caucasian patients. A higher percentage (30%) of the Black patients were diagnosed with diabetes mellitus compared to Caucasians (11%). Multivariable logistic regression revealed that performance of the colonoscopy by academic gastroenterologists was associated with higher precancerous polyp detection compared to contractual nonacademic gastroenterologists (OR 1.69 95% CI 1.32-2.17, p&lt;0.0001). Because of this observation, a physician feedback program was initiated, and as of 2017 the polyp detection rates at all three institutions reached 25%. In addition, multivariable analysis also identified older age (OR 1.03/year 95% CI 1,01-1,04 p= 0.0006), male sex (OR 1.60 95%CI 1.32-2.00 p&lt;0.0001), current smoking (1.52 95% CI 1.32-2.17 p&lt;0.0001) and diabetes mellitus (OR 1.27 95% CI 0.99-1.63 p = 0.062) as associated with higher precancerous colon polyp detection or adenoma detection rate (ADR). Neither race, ethnicity, BMI, nor insurance was significantly associated with detection rates. Conclusions: It is imperative that metrics of polyp detection rates be routinely monitored to ensure that all patients have access to high-quality screening colonoscopies. A prospective observational cohort study will help further identify factors associated with precancerous polyp detection, now that variations in operator detection rates have been addressed. Citation Format: Yakira David, Lorenzo Ottaviano, Jihye Park, Sadat Iqbal, Michelle Likhtshteyn, Samir Kumar, Helen Lyo, Ayanna Lewis, Brandon Lung, Jesse Frye, Li Huang, Ellen Li, Jie Yang, Laura Martello, Shivakumar Vignesh, Joshua Miller, Evan Grossman. Factors contributing to precancerous polyp detection in initial screening colonoscopies [abstract]. In: Proceedings of the Eleventh AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2018 Nov 2-5; New Orleans, LA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl):Abstract nr B102." @default.
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• W3048700906 date "2020-06-01" @default.
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• W3048700906 title "Abstract B102: Factors contributing to precancerous polyp detection in initial screening colonoscopies" @default.
• W3048700906 doi "https://doi.org/10.1158/1538-7755.disp18-b102" @default.
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