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• W3048703339 endingPage "1886" @default.
• W3048703339 startingPage "1886" @default.
• W3048703339 abstract "Ischemic heart disease is currently a major cause of mortality and morbidity worldwide. Nevertheless, the actual therapeutic scenario does not target myocardial cell regeneration and consequently, the progression toward the late stage of chronic heart failure is common. Endothelial progenitor cells (EPCs) are bone marrow-derived stem cells that contribute to the homeostasis of the endothelial wall in acute and chronic ischemic disease. Calcium modulation and other molecular pathways (NOTCH, VEGFR, and CXCR4) contribute to EPC proliferation and differentiation. The present review provides a summary of EPC biology with a particular focus on the regulatory pathways of EPCs and describes promising applications for cardiovascular cell therapy." @default.
• W3048703339 created "2020-08-18" @default.
• W3048703339 creator A5015069411 @default.
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• W3048703339 creator A5073156493 @default.
• W3048703339 creator A5073409422 @default.
• W3048703339 date "2020-08-11" @default.
• W3048703339 modified "2023-10-16" @default.
• W3048703339 title "The State of Art of Regenerative Therapy in Cardiovascular Ischemic Disease: Biology, Signaling Pathways, and Epigenetics of Endothelial Progenitor Cells" @default.
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