Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048732069> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3048732069 endingPage "1132" @default.
- W3048732069 startingPage "1128" @default.
- W3048732069 abstract "Summary Background Fungal keratitis can be more difficult to treat than bacterial keratitis with worse outcomes. Objective To evaluate the therapeutic response time of topical voriconazole combined with intrastromal voriconazole, and topical natamycin on Fusarium keratitis. Methods The stroma of corneas of twelve New Zealand White rabbits was inoculated with Fusarium sp spores. Seven days after inoculation, they were divided into 2 groups randomly. Group A was treated with topical natamycin 5% for 21 days. Group B was treated with intrastromal voriconazole 0.05% single injection at the beginning of treatment, continued with topical voriconazole 1% for 21 days. Clinical evaluations for epithelial defect size and clinical scores in each group were performed on 1st, 3rd, 7th, 10th, 14th and 21st days after treatment. Mycological examinations were performed before and after the treatment. Results After treatment, there was no statistically significant difference between natamycin and voriconazole in reducing epithelial defect size at first, second or third week after treatment ( P = .15; P = .39; and P = .90). The clinical scores on both groups also showed no statistically significant differences at first, second and third weeks after treatment ( P = .24; P = .09; and P = .32). Qualitative mycological evaluation before and after the treatment showed no statistically significant difference in KOH examination ( P = 1; P = 1) and culture in Sabouraud dextrose agar ( P = 1; P = 1). Conclusion Intrastromal voriconazole injection combined with topical voriconazole seems to give similar response time but not earlier in improving clinical presentation of Fusarium keratitis as topical natamycin." @default.
- W3048732069 created "2020-08-18" @default.
- W3048732069 creator A5008762753 @default.
- W3048732069 creator A5041140569 @default.
- W3048732069 creator A5050925436 @default.
- W3048732069 creator A5059696534 @default.
- W3048732069 date "2020-09-04" @default.
- W3048732069 modified "2023-10-18" @default.
- W3048732069 title "Therapeutic response time of topical voriconazole 1% and intrastromal voriconazole 0.05% versus topical natamycin 5% monotherapy in <i>Fusarium</i> keratitis in rabbit" @default.
- W3048732069 cites W1423075642 @default.
- W3048732069 cites W1554414824 @default.
- W3048732069 cites W1903365558 @default.
- W3048732069 cites W2019513344 @default.
- W3048732069 cites W2021382181 @default.
- W3048732069 cites W2049880056 @default.
- W3048732069 cites W2062103118 @default.
- W3048732069 cites W2064185190 @default.
- W3048732069 cites W2069702799 @default.
- W3048732069 cites W2076379908 @default.
- W3048732069 cites W2081542706 @default.
- W3048732069 cites W2120929255 @default.
- W3048732069 cites W2134033832 @default.
- W3048732069 cites W2156947972 @default.
- W3048732069 cites W2159093932 @default.
- W3048732069 cites W2160872671 @default.
- W3048732069 cites W2162773145 @default.
- W3048732069 cites W2163099413 @default.
- W3048732069 cites W2407547081 @default.
- W3048732069 cites W2803366880 @default.
- W3048732069 doi "https://doi.org/10.1111/myc.13160" @default.
- W3048732069 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32780874" @default.
- W3048732069 hasPublicationYear "2020" @default.
- W3048732069 type Work @default.
- W3048732069 sameAs 3048732069 @default.
- W3048732069 citedByCount "3" @default.
- W3048732069 countsByYear W30487320692021 @default.
- W3048732069 countsByYear W30487320692022 @default.
- W3048732069 crossrefType "journal-article" @default.
- W3048732069 hasAuthorship W3048732069A5008762753 @default.
- W3048732069 hasAuthorship W3048732069A5041140569 @default.
- W3048732069 hasAuthorship W3048732069A5050925436 @default.
- W3048732069 hasAuthorship W3048732069A5059696534 @default.
- W3048732069 hasConcept C142724271 @default.
- W3048732069 hasConcept C144027150 @default.
- W3048732069 hasConcept C16005928 @default.
- W3048732069 hasConcept C2776079991 @default.
- W3048732069 hasConcept C2778560704 @default.
- W3048732069 hasConcept C2778867309 @default.
- W3048732069 hasConcept C2779117757 @default.
- W3048732069 hasConcept C2779548794 @default.
- W3048732069 hasConcept C2780690907 @default.
- W3048732069 hasConcept C71924100 @default.
- W3048732069 hasConcept C86803240 @default.
- W3048732069 hasConceptScore W3048732069C142724271 @default.
- W3048732069 hasConceptScore W3048732069C144027150 @default.
- W3048732069 hasConceptScore W3048732069C16005928 @default.
- W3048732069 hasConceptScore W3048732069C2776079991 @default.
- W3048732069 hasConceptScore W3048732069C2778560704 @default.
- W3048732069 hasConceptScore W3048732069C2778867309 @default.
- W3048732069 hasConceptScore W3048732069C2779117757 @default.
- W3048732069 hasConceptScore W3048732069C2779548794 @default.
- W3048732069 hasConceptScore W3048732069C2780690907 @default.
- W3048732069 hasConceptScore W3048732069C71924100 @default.
- W3048732069 hasConceptScore W3048732069C86803240 @default.
- W3048732069 hasIssue "10" @default.
- W3048732069 hasLocation W30487320691 @default.
- W3048732069 hasOpenAccess W3048732069 @default.
- W3048732069 hasPrimaryLocation W30487320691 @default.
- W3048732069 hasRelatedWork W1545633885 @default.
- W3048732069 hasRelatedWork W1981968855 @default.
- W3048732069 hasRelatedWork W2013249577 @default.
- W3048732069 hasRelatedWork W2112693094 @default.
- W3048732069 hasRelatedWork W2530791194 @default.
- W3048732069 hasRelatedWork W2612870821 @default.
- W3048732069 hasRelatedWork W2767561229 @default.
- W3048732069 hasRelatedWork W2980524740 @default.
- W3048732069 hasRelatedWork W3014329025 @default.
- W3048732069 hasRelatedWork W4376105979 @default.
- W3048732069 hasVolume "63" @default.
- W3048732069 isParatext "false" @default.
- W3048732069 isRetracted "false" @default.
- W3048732069 magId "3048732069" @default.
- W3048732069 workType "article" @default.