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- W3048761217 abstract "Autism spectrum disorders (ASDs) constitute a set of heterogeneous neurodevelopmental conditions, characterized by a wide genetic variability that has led to hypothesize a polygenic origin. The metabolic profiles of patients with ASD suggest a possible implication of mitochondrial pathways. Although different physiological and biochemical studies reported deficits in mitochondrial oxidative phosphorylation in subjects with ASD, the role of mitochondrial DNA variations has remained relatively unexplored. In this review, we report and discuss very recent evidence to demonstrate the key role of mitochondrial disorders in the development of ASD." @default.
- W3048761217 created "2020-08-18" @default.
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- W3048761217 date "2020-08-12" @default.
- W3048761217 modified "2023-10-16" @default.
- W3048761217 title "The Mitochondrial Dysfunction Hypothesis in Autism Spectrum Disorders: Current Status and Future Perspectives" @default.
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- W3048761217 doi "https://doi.org/10.3390/ijms21165785" @default.
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