Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048763642> ?p ?o ?g. }
- W3048763642 abstract "Abstract Background The outbreak of a new virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has now become the main health concern all over the world. Since effective antiviral treatments have not been developed until now, SARS-CoV-2 is severely affecting countries and territories around the world. Methods At the present review, articles in PubMed were searched with the following terms: mesenchymal stem cells, exosomes, coronavirus, and SARS-CoV-2, either alone or in a combination form. The most relevant selected functions were mesenchymal stem cell-derived exosomes and SARS-CoV-2 virus infection. Results SARS-CoV-2 could damage pulmonary cells and induce secretion of different types of inflammatory cytokines. In the following, these cytokines trigger inflammation that damages the lungs and results in lethal acute respiratory distress syndrome (ARDS). The main characteristic of ARDS is the onset of inflammation in pulmonary, hyaline formation, pulmonary fibrosis, and edema. Mesenchymal stem cell-derived exosomes (MSC-Exo) are believed to have anti-inflammatory effects and immune-modulating capacity as well as the ability to induce tissue regeneration, suggesting a significant therapeutic opportunity that could be used to SARS-CoV-2 pneumonia treatment. Besides, exosomes may serve as a biomarker, drug delivery system, and vaccine for the management of the patient with SARS-CoV-2. Conclusion MSC-Exo may serve as a promising tool in the treatment of SARS-CoV-2 pneumonia. However, further work needs to be carried out to confirm the efficacy of exosomes in the treatment of SARS-CoV-2 pneumonia." @default.
- W3048763642 created "2020-08-18" @default.
- W3048763642 creator A5017962255 @default.
- W3048763642 creator A5045532081 @default.
- W3048763642 date "2020-08-14" @default.
- W3048763642 modified "2023-10-01" @default.
- W3048763642 title "Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia" @default.
- W3048763642 cites W1964674805 @default.
- W3048763642 cites W1966606134 @default.
- W3048763642 cites W1982323513 @default.
- W3048763642 cites W1986847770 @default.
- W3048763642 cites W2031173953 @default.
- W3048763642 cites W2041302930 @default.
- W3048763642 cites W2060387475 @default.
- W3048763642 cites W2066426973 @default.
- W3048763642 cites W2085554170 @default.
- W3048763642 cites W2103839702 @default.
- W3048763642 cites W2103872250 @default.
- W3048763642 cites W2105149323 @default.
- W3048763642 cites W2112147913 @default.
- W3048763642 cites W2114754360 @default.
- W3048763642 cites W2123417019 @default.
- W3048763642 cites W2132260239 @default.
- W3048763642 cites W2136773221 @default.
- W3048763642 cites W2138704758 @default.
- W3048763642 cites W2143729276 @default.
- W3048763642 cites W2144467901 @default.
- W3048763642 cites W2158682140 @default.
- W3048763642 cites W2159401023 @default.
- W3048763642 cites W2168031418 @default.
- W3048763642 cites W2168446943 @default.
- W3048763642 cites W2177788064 @default.
- W3048763642 cites W2296337888 @default.
- W3048763642 cites W2306794997 @default.
- W3048763642 cites W2317566123 @default.
- W3048763642 cites W2340631986 @default.
- W3048763642 cites W2418849288 @default.
- W3048763642 cites W2472556431 @default.
- W3048763642 cites W2540193686 @default.
- W3048763642 cites W2558608698 @default.
- W3048763642 cites W2578115077 @default.
- W3048763642 cites W2597520820 @default.
- W3048763642 cites W2753884258 @default.
- W3048763642 cites W2795369145 @default.
- W3048763642 cites W2796493184 @default.
- W3048763642 cites W2884219039 @default.
- W3048763642 cites W2892499513 @default.
- W3048763642 cites W2896759930 @default.
- W3048763642 cites W2900226360 @default.
- W3048763642 cites W2900756811 @default.
- W3048763642 cites W2906497397 @default.
- W3048763642 cites W2914833536 @default.
- W3048763642 cites W2919824502 @default.
- W3048763642 cites W2922377426 @default.
- W3048763642 cites W2943233832 @default.
- W3048763642 cites W2944196444 @default.
- W3048763642 cites W2947753663 @default.
- W3048763642 cites W2963034931 @default.
- W3048763642 cites W2964930843 @default.
- W3048763642 cites W2968810602 @default.
- W3048763642 cites W2970654566 @default.
- W3048763642 cites W2976973875 @default.
- W3048763642 cites W2977617462 @default.
- W3048763642 cites W2981426204 @default.
- W3048763642 cites W2981960056 @default.
- W3048763642 cites W2995667982 @default.
- W3048763642 cites W2996890300 @default.
- W3048763642 cites W2999409984 @default.
- W3048763642 cites W3001118548 @default.
- W3048763642 cites W3002108456 @default.
- W3048763642 cites W3002539152 @default.
- W3048763642 cites W3002731232 @default.
- W3048763642 cites W3004280078 @default.
- W3048763642 cites W3005655936 @default.
- W3048763642 cites W3006000165 @default.
- W3048763642 cites W3006887307 @default.
- W3048763642 cites W3006961006 @default.
- W3048763642 cites W3007238890 @default.
- W3048763642 cites W3007678386 @default.
- W3048763642 cites W3007940623 @default.
- W3048763642 cites W3008452791 @default.
- W3048763642 cites W3008827533 @default.
- W3048763642 cites W3009379198 @default.
- W3048763642 cites W3009859788 @default.
- W3048763642 cites W3009885589 @default.
- W3048763642 cites W3009906937 @default.
- W3048763642 cites W3010233963 @default.
- W3048763642 cites W3011127849 @default.
- W3048763642 cites W3011568661 @default.
- W3048763642 cites W3011802905 @default.
- W3048763642 cites W3012253443 @default.
- W3048763642 cites W3012364352 @default.
- W3048763642 cites W3013176450 @default.
- W3048763642 cites W3014003872 @default.
- W3048763642 cites W3017434281 @default.
- W3048763642 cites W3021841162 @default.
- W3048763642 cites W3023991776 @default.
- W3048763642 cites W3041206342 @default.
- W3048763642 cites W311927316 @default.
- W3048763642 cites W3165656738 @default.