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• W3048784557 startingPage "91" @default.
• W3048784557 abstract "There is a large unmet medical need to find disease modifying therapies against neurodegenerative diseases. This review summarizes data indicating that insulin resistance occurs in neurodegeneration and strategies to normalize insulin sensitivity in neurons may provide neuroprotective actions. In particular, recent preclinical and clinical studies in Parkinson's disease and Alzheimer's disease have indicated that glucagon-like peptide 1 (GLP1) agonism and dipeptidyl peptidase-4 inhibition may exert neuroprotection. Mechanistic insights from these studies and future directions for drug development against neurodegeneration based on GLP1 agonism are discussed." @default.
• W3048784557 created "2020-08-18" @default.
• W3048784557 creator A5021108404 @default.
• W3048784557 creator A5036364090 @default.
• W3048784557 creator A5044453358 @default.
• W3048784557 creator A5083048222 @default.
• W3048784557 date "2020-01-01" @default.
• W3048784557 modified "2023-10-02" @default.
• W3048784557 title "Repurposing GLP1 agonists for neurodegenerative diseases" @default.
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