FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048896188> ?p ?o ?g. }

• W3048896188 endingPage "420" @default.
• W3048896188 startingPage "420" @default.
• W3048896188 abstract "Scaffold material is essential in providing mechanical support to tissue, allowing stem cells to improve their function in the healing and repair of trauma sites and tissue regeneration. The scaffold aids cell organization in the damaged tissue. It serves and allows bio mimicking the mechanical and biological properties of the target tissue and facilitates cell proliferation and differentiation at the regeneration site. In this study, the developed and assayed bio-composite made of unique collagen fibers and alginate hydrogel supports the function of cells around the implanted material. We used an in vivo rat model to study the scaffold effects when transplanted subcutaneously and as an augment for tendon repair. Animals’ well-being was measured by their weight and daily activity post scaffold transplantation during their recovery. At the end of the experiment, the bio-composite was histologically examined, and the surrounding tissues around the implant were evaluated for inflammation reaction and scarring tissue. In the histology, the formation of granulation tissue and fibroblasts that were part of the inclusion process of the implanted material were noted. At the transplanted sites, inflammatory cells, such as plasma cells, macrophages, and giant cells, were also observed as expected at this time point post transplantation. This study demonstrated not only the collagen-alginate device biocompatibility, with no cytotoxic effects on the analyzed rats, but also that the 3D structure enables cell migration and new blood vessel formation needed for tissue repair. Overall, the results of the current study proved for the first time that the implantable scaffold for long-term confirms the well-being of these rats and is correspondence to biocompatibility ISO standards and can be further developed for medical devices application." @default.
• W3048896188 created "2020-08-18" @default.
• W3048896188 creator A5004908882 @default.
• W3048896188 creator A5011059517 @default.
• W3048896188 creator A5014567293 @default.
• W3048896188 creator A5035698889 @default.
• W3048896188 creator A5073891704 @default.
• W3048896188 creator A5081982391 @default.
• W3048896188 creator A5090180695 @default.
• W3048896188 date "2020-08-11" @default.
• W3048896188 modified "2023-09-23" @default.
• W3048896188 title "Biocompatibility of a Marine Collagen-Based Scaffold In Vitro and In Vivo" @default.
• W3048896188 cites W1545517840 @default.
• W3048896188 cites W1980228999 @default.
• W3048896188 cites W1981269419 @default.
• W3048896188 cites W1996584907 @default.
• W3048896188 cites W2013411867 @default.
• W3048896188 cites W2016578709 @default.
• W3048896188 cites W2036077057 @default.
• W3048896188 cites W2047075715 @default.
• W3048896188 cites W2049880533 @default.
• W3048896188 cites W2123413801 @default.
• W3048896188 cites W2422073370 @default.
• W3048896188 cites W2509593708 @default.
• W3048896188 cites W2557990228 @default.
• W3048896188 cites W2618809394 @default.
• W3048896188 cites W2736116080 @default.
• W3048896188 cites W2789518618 @default.
• W3048896188 cites W2791661278 @default.
• W3048896188 cites W2912770495 @default.
• W3048896188 cites W3003694531 @default.
• W3048896188 cites W3012163302 @default.
• W3048896188 cites W779751827 @default.
• W3048896188 doi "https://doi.org/10.3390/md18080420" @default.
• W3048896188 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7460003" @default.
• W3048896188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32796603" @default.
• W3048896188 hasPublicationYear "2020" @default.
• W3048896188 type Work @default.
• W3048896188 sameAs 3048896188 @default.
• W3048896188 citedByCount "21" @default.
• W3048896188 countsByYear W30488961882021 @default.
• W3048896188 countsByYear W30488961882022 @default.
• W3048896188 countsByYear W30488961882023 @default.
• W3048896188 crossrefType "journal-article" @default.
• W3048896188 hasAuthorship W3048896188A5004908882 @default.
• W3048896188 hasAuthorship W3048896188A5011059517 @default.
• W3048896188 hasAuthorship W3048896188A5014567293 @default.
• W3048896188 hasAuthorship W3048896188A5035698889 @default.
• W3048896188 hasAuthorship W3048896188A5073891704 @default.
• W3048896188 hasAuthorship W3048896188A5081982391 @default.
• W3048896188 hasAuthorship W3048896188A5090180695 @default.
• W3048896188 hasBestOaLocation W30488961881 @default.
• W3048896188 hasConcept C108657112 @default.
• W3048896188 hasConcept C136229726 @default.
• W3048896188 hasConcept C141071460 @default.
• W3048896188 hasConcept C142724271 @default.
• W3048896188 hasConcept C150903083 @default.
• W3048896188 hasConcept C171056886 @default.
• W3048896188 hasConcept C178790620 @default.
• W3048896188 hasConcept C185592680 @default.
• W3048896188 hasConcept C192562407 @default.
• W3048896188 hasConcept C198826908 @default.
• W3048896188 hasConcept C203014093 @default.
• W3048896188 hasConcept C207001950 @default.
• W3048896188 hasConcept C2776055305 @default.
• W3048896188 hasConcept C2777230088 @default.
• W3048896188 hasConcept C2780269544 @default.
• W3048896188 hasConcept C2911091166 @default.
• W3048896188 hasConcept C49892992 @default.
• W3048896188 hasConcept C71924100 @default.
• W3048896188 hasConcept C86803240 @default.
• W3048896188 hasConcept C89429830 @default.
• W3048896188 hasConcept C95444343 @default.
• W3048896188 hasConceptScore W3048896188C108657112 @default.
• W3048896188 hasConceptScore W3048896188C136229726 @default.
• W3048896188 hasConceptScore W3048896188C141071460 @default.
• W3048896188 hasConceptScore W3048896188C142724271 @default.
• W3048896188 hasConceptScore W3048896188C150903083 @default.
• W3048896188 hasConceptScore W3048896188C171056886 @default.
• W3048896188 hasConceptScore W3048896188C178790620 @default.
• W3048896188 hasConceptScore W3048896188C185592680 @default.
• W3048896188 hasConceptScore W3048896188C192562407 @default.
• W3048896188 hasConceptScore W3048896188C198826908 @default.
• W3048896188 hasConceptScore W3048896188C203014093 @default.
• W3048896188 hasConceptScore W3048896188C207001950 @default.
• W3048896188 hasConceptScore W3048896188C2776055305 @default.
• W3048896188 hasConceptScore W3048896188C2777230088 @default.
• W3048896188 hasConceptScore W3048896188C2780269544 @default.
• W3048896188 hasConceptScore W3048896188C2911091166 @default.
• W3048896188 hasConceptScore W3048896188C49892992 @default.
• W3048896188 hasConceptScore W3048896188C71924100 @default.
• W3048896188 hasConceptScore W3048896188C86803240 @default.
• W3048896188 hasConceptScore W3048896188C89429830 @default.
• W3048896188 hasConceptScore W3048896188C95444343 @default.
• W3048896188 hasIssue "8" @default.
• W3048896188 hasLocation W30488961881 @default.
• W3048896188 hasLocation W30488961882 @default.
• W3048896188 hasOpenAccess W3048896188 @default.

• next