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• W3048906500 abstract "ABSTRACT There is a pressing need for evidence-based scrutiny of plans to re-open childcare during the COVID-19 pandemic. Here we developed an agent-based model of SARS-CoV-2 transmission within a childcare center and households. Scenarios varied the student-to-educator ratio (15:2, 8:2, 7:3), and family clustering (siblings together vs. random assignment). We also evaluated a primary school setting (30:1, 15:1 and 8:1) including cohorts that alternate weekly. In the childcare scenarios, grouping siblings significantly reduced outbreak size and student-days lost. We identify an intensification cascade specific to classroom outbreaks of respiratory viruses with presymptomatic infection. In both childcare and primary school settings, each doubling of class size from 8 to 15 to 30 more than doubled the outbreak size and student-days lost, by factors of 2-5, respectively 2.5-4.5, depending on the scenario. Proposals for childcare and primary school reopening could be enhanced for safety by switching to lower ratios and sibling groupings." @default.
• W3048906500 created "2020-08-18" @default.
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• W3048906500 date "2020-08-11" @default.
• W3048906500 modified "2023-10-16" @default.
• W3048906500 title "Model-based projections for COVID-19 outbreak size and student-days lost to closure in Ontario childcare centers and primary schools" @default.
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• W3048906500 doi "https://doi.org/10.1101/2020.08.07.20170407" @default.
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