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- W3048985551 abstract "The killing of Escherichia coli cells by H 2 O 2 is higher when exposure to the oxidant is performed in a complete culture medium, as compared to saline. Whereas MgSO 4, CaCl 2 , thiamine or glucose, added separately or in combination with the saline, had no effect on the cytotoxic response to H 2 O 2 , the cytotoxicity appeared highly dependent upon the presence of the casamino acids in the incubation medium. One of these amino acids, histidine, was found to greatly augment the toxicity of H 2 O 2 in E. coli. This effect of histidine was also observed in mammalian cells. In fact, both the cytoxicity and the DNA damage produced by H 2 O 2 in Chinese hamster ovary (CHO) cells were significantly increased by this amino acid." @default.
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- W3048985551 date "1991-02-01" @default.
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- W3048985551 title "Exogenous Histidine as a Co-factor which Exacerbates the Toxicity of Hydrogen Peroxide in Cultured Mammalian and Bacterial Cells" @default.
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- W3048985551 doi "https://doi.org/10.1177/026119299101900113" @default.
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