Matches in SemOpenAlex for { <https://semopenalex.org/work/W3048996658> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3048996658 abstract "Heparin and citrate are commonly used anticoagulants in membrane/adsorption based extracorporeal liver support systems. However, anion exchange resins employed for the removal of negatively charged target molecules including bilirubin may also deplete these anticoagulants due to their negative charge. The aim of this study was to evaluate the adsorption of citrate by anion exchange resins and the impact on extracorporeal Ca2+ concentrations.Liver support treatments were simulated in vitro. Citrate and Ca2+ concentrations were measured pre and post albumin filter as well as pre and post adsorbents. In addition, batch experiments were performed to quantify citrate adsorption.Pre albumin filter target Ca2+ concentrations were reached well with only minor deviations. Citrate was adsorbed by anion exchange resins, resulting in a higher Ca2+ concentration downstream of the adsorbent cartridges during the first hour of treatment.The anion exchange resin depletes citrate, leading to an increased Ca2+ concentration in the extracorporeal circuit, which may cause an increased risk of clotting during the first hour of treatment. An increase of citrate infusion during the first hour of treatment should therefore be considered to compensate for the adsorption of citrate." @default.
- W3048996658 created "2020-08-21" @default.
- W3048996658 creator A5007559704 @default.
- W3048996658 creator A5039544367 @default.
- W3048996658 creator A5059199102 @default.
- W3048996658 creator A5060383962 @default.
- W3048996658 creator A5080471825 @default.
- W3048996658 date "2020-08-13" @default.
- W3048996658 modified "2023-10-03" @default.
- W3048996658 title "Impact of anion exchange adsorbents on regional citrate anticoagulation" @default.
- W3048996658 cites W1601234518 @default.
- W3048996658 cites W1798010974 @default.
- W3048996658 cites W1971431348 @default.
- W3048996658 cites W1973538134 @default.
- W3048996658 cites W1979830318 @default.
- W3048996658 cites W2010220557 @default.
- W3048996658 cites W2012435822 @default.
- W3048996658 cites W2023002422 @default.
- W3048996658 cites W2042106768 @default.
- W3048996658 cites W2092391604 @default.
- W3048996658 cites W2100972869 @default.
- W3048996658 cites W2137589680 @default.
- W3048996658 cites W2145378282 @default.
- W3048996658 cites W2169985183 @default.
- W3048996658 cites W2474397295 @default.
- W3048996658 cites W2562341973 @default.
- W3048996658 cites W2587810133 @default.
- W3048996658 cites W2601137875 @default.
- W3048996658 cites W2894148169 @default.
- W3048996658 cites W2952094345 @default.
- W3048996658 cites W4249438407 @default.
- W3048996658 doi "https://doi.org/10.1177/0391398820947733" @default.
- W3048996658 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7944420" @default.
- W3048996658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32787606" @default.
- W3048996658 hasPublicationYear "2020" @default.
- W3048996658 type Work @default.
- W3048996658 sameAs 3048996658 @default.
- W3048996658 citedByCount "0" @default.
- W3048996658 crossrefType "journal-article" @default.
- W3048996658 hasAuthorship W3048996658A5007559704 @default.
- W3048996658 hasAuthorship W3048996658A5039544367 @default.
- W3048996658 hasAuthorship W3048996658A5059199102 @default.
- W3048996658 hasAuthorship W3048996658A5060383962 @default.
- W3048996658 hasAuthorship W3048996658A5080471825 @default.
- W3048996658 hasBestOaLocation W30489966581 @default.
- W3048996658 hasConcept C117760992 @default.
- W3048996658 hasConcept C13965031 @default.
- W3048996658 hasConcept C141071460 @default.
- W3048996658 hasConcept C145148216 @default.
- W3048996658 hasConcept C150394285 @default.
- W3048996658 hasConcept C178790620 @default.
- W3048996658 hasConcept C185592680 @default.
- W3048996658 hasConcept C2776125364 @default.
- W3048996658 hasConcept C2777557582 @default.
- W3048996658 hasConcept C2779032678 @default.
- W3048996658 hasConcept C2779915274 @default.
- W3048996658 hasConcept C41625074 @default.
- W3048996658 hasConcept C43617362 @default.
- W3048996658 hasConcept C55493867 @default.
- W3048996658 hasConcept C71924100 @default.
- W3048996658 hasConceptScore W3048996658C117760992 @default.
- W3048996658 hasConceptScore W3048996658C13965031 @default.
- W3048996658 hasConceptScore W3048996658C141071460 @default.
- W3048996658 hasConceptScore W3048996658C145148216 @default.
- W3048996658 hasConceptScore W3048996658C150394285 @default.
- W3048996658 hasConceptScore W3048996658C178790620 @default.
- W3048996658 hasConceptScore W3048996658C185592680 @default.
- W3048996658 hasConceptScore W3048996658C2776125364 @default.
- W3048996658 hasConceptScore W3048996658C2777557582 @default.
- W3048996658 hasConceptScore W3048996658C2779032678 @default.
- W3048996658 hasConceptScore W3048996658C2779915274 @default.
- W3048996658 hasConceptScore W3048996658C41625074 @default.
- W3048996658 hasConceptScore W3048996658C43617362 @default.
- W3048996658 hasConceptScore W3048996658C55493867 @default.
- W3048996658 hasConceptScore W3048996658C71924100 @default.
- W3048996658 hasFunder F4320320300 @default.
- W3048996658 hasLocation W30489966581 @default.
- W3048996658 hasLocation W30489966582 @default.
- W3048996658 hasLocation W30489966583 @default.
- W3048996658 hasOpenAccess W3048996658 @default.
- W3048996658 hasPrimaryLocation W30489966581 @default.
- W3048996658 hasRelatedWork W10355975 @default.
- W3048996658 hasRelatedWork W15920736 @default.
- W3048996658 hasRelatedWork W22251907 @default.
- W3048996658 hasRelatedWork W22315602 @default.
- W3048996658 hasRelatedWork W24727035 @default.
- W3048996658 hasRelatedWork W28755149 @default.
- W3048996658 hasRelatedWork W3010292 @default.
- W3048996658 hasRelatedWork W3028592 @default.
- W3048996658 hasRelatedWork W38398033 @default.
- W3048996658 hasRelatedWork W5512242 @default.
- W3048996658 isParatext "false" @default.
- W3048996658 isRetracted "false" @default.
- W3048996658 magId "3048996658" @default.
- W3048996658 workType "article" @default.