FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3049012004> ?p ?o ?g. }

• W3049012004 endingPage "44" @default.
• W3049012004 startingPage "33" @default.
• W3049012004 abstract "Ischemic heart disease is an imperative cause of high morbidity and mortality globally. The cardiac ischemia/reperfusion damage occur in both reperfusion and ischemia.In this exploration, we have planned to examine the cardio-protective action of phyllanthin against the myocardial ischemic-reperfusion injury in mice.The myocardial ischemic reperfusion injury (MI-RI) stimulated via coronary artery occlusion, followed by the 10 mg/kg of phyllanthin treatment. The serum cardiac markers and pro-inflammatory markers level was investigated by using the assay kits. The expressions of oxidative stress and inflammatory markers level were investigated by immunohistochemical analysis. Lipid peroxidation, antioxidant enzymes, and ATPase levels level was examined by standard methods. The expression of oxidative stress markers were inspected by the reverse transcription polymerase chain reaction technique. The heart histology was investigated microscopically.The phyllanthin treatment increased the body weight, and heart weight also diminished the infarct size in the MI/RI mice. Cardiac markers status was diminished and the blood pressure markers were augmented by the phyllanthin. Histological analysis revealed the protective role of phyllanthin. Suppressed lipid peroxidation and enhanced antioxidant enzymes were noted in the phyllanthin treated mice MI-RI mice. Phyllanthin appreciably suppressed the pro-inflammatory regulators that is, NF-αB p65, IL-6, IL-1β, and TNF-α and enhanced the antioxidant marker expressions. ATPase levels were improved by the phyllanthin in the MI-RI mice.These novel findings were confirmed the therapeutic role of phyllanthin against the MI-RI in mice. Hence, it can be a promising agent to treat the MI-RI induced cardiac dysfunction." @default.
• W3049012004 created "2020-08-21" @default.
• W3049012004 creator A5013395751 @default.
• W3049012004 creator A5021202119 @default.
• W3049012004 creator A5023859325 @default.
• W3049012004 creator A5026570441 @default.
• W3049012004 creator A5055072758 @default.
• W3049012004 date "2020-08-14" @default.
• W3049012004 modified "2023-10-01" @default.
• W3049012004 title "Cardioprotective role of phyllanthin against myocardial ischemia‐reperfusion injury by alleviating oxidative stress and inflammation with increased adenosine triphosphate levels in the mice model" @default.
• W3049012004 cites W1698414284 @default.
• W3049012004 cites W1766430993 @default.
• W3049012004 cites W1876724481 @default.
• W3049012004 cites W1987710388 @default.
• W3049012004 cites W1995382021 @default.
• W3049012004 cites W1999718232 @default.
• W3049012004 cites W2011945821 @default.
• W3049012004 cites W2018893722 @default.
• W3049012004 cites W2045230446 @default.
• W3049012004 cites W2060194897 @default.
• W3049012004 cites W2066751367 @default.
• W3049012004 cites W2079351469 @default.
• W3049012004 cites W2082198711 @default.
• W3049012004 cites W2088866343 @default.
• W3049012004 cites W2089817086 @default.
• W3049012004 cites W2096795975 @default.
• W3049012004 cites W2116380600 @default.
• W3049012004 cites W2140526577 @default.
• W3049012004 cites W2153435210 @default.
• W3049012004 cites W2170679758 @default.
• W3049012004 cites W2172392063 @default.
• W3049012004 cites W2178392730 @default.
• W3049012004 cites W2281735941 @default.
• W3049012004 cites W2336123998 @default.
• W3049012004 cites W2416735797 @default.
• W3049012004 cites W2518513835 @default.
• W3049012004 cites W2553588794 @default.
• W3049012004 cites W2570101639 @default.
• W3049012004 cites W2597778896 @default.
• W3049012004 cites W2606648150 @default.
• W3049012004 cites W2609439463 @default.
• W3049012004 cites W2753159170 @default.
• W3049012004 cites W2767207189 @default.
• W3049012004 cites W2784299734 @default.
• W3049012004 cites W2906230290 @default.
• W3049012004 cites W2913705661 @default.
• W3049012004 cites W2917893878 @default.
• W3049012004 cites W2944994332 @default.
• W3049012004 cites W3016477856 @default.
• W3049012004 doi "https://doi.org/10.1002/tox.23008" @default.
• W3049012004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32798296" @default.
• W3049012004 hasPublicationYear "2020" @default.
• W3049012004 type Work @default.
• W3049012004 sameAs 3049012004 @default.
• W3049012004 citedByCount "6" @default.
• W3049012004 countsByYear W30490120042021 @default.
• W3049012004 countsByYear W30490120042022 @default.
• W3049012004 countsByYear W30490120042023 @default.
• W3049012004 crossrefType "journal-article" @default.
• W3049012004 hasAuthorship W3049012004A5013395751 @default.
• W3049012004 hasAuthorship W3049012004A5021202119 @default.
• W3049012004 hasAuthorship W3049012004A5023859325 @default.
• W3049012004 hasAuthorship W3049012004A5026570441 @default.
• W3049012004 hasAuthorship W3049012004A5055072758 @default.
• W3049012004 hasConcept C126322002 @default.
• W3049012004 hasConcept C185592680 @default.
• W3049012004 hasConcept C2776151105 @default.
• W3049012004 hasConcept C2776914184 @default.
• W3049012004 hasConcept C2778004101 @default.
• W3049012004 hasConcept C2780114680 @default.
• W3049012004 hasConcept C2780829032 @default.
• W3049012004 hasConcept C541997718 @default.
• W3049012004 hasConcept C55493867 @default.
• W3049012004 hasConcept C71924100 @default.
• W3049012004 hasConcept C98274493 @default.
• W3049012004 hasConceptScore W3049012004C126322002 @default.
• W3049012004 hasConceptScore W3049012004C185592680 @default.
• W3049012004 hasConceptScore W3049012004C2776151105 @default.
• W3049012004 hasConceptScore W3049012004C2776914184 @default.
• W3049012004 hasConceptScore W3049012004C2778004101 @default.
• W3049012004 hasConceptScore W3049012004C2780114680 @default.
• W3049012004 hasConceptScore W3049012004C2780829032 @default.
• W3049012004 hasConceptScore W3049012004C541997718 @default.
• W3049012004 hasConceptScore W3049012004C55493867 @default.
• W3049012004 hasConceptScore W3049012004C71924100 @default.
• W3049012004 hasConceptScore W3049012004C98274493 @default.
• W3049012004 hasIssue "1" @default.
• W3049012004 hasLocation W30490120041 @default.
• W3049012004 hasLocation W30490120042 @default.
• W3049012004 hasOpenAccess W3049012004 @default.
• W3049012004 hasPrimaryLocation W30490120041 @default.
• W3049012004 hasRelatedWork W1470000624 @default.
• W3049012004 hasRelatedWork W2095014063 @default.
• W3049012004 hasRelatedWork W2147002759 @default.
• W3049012004 hasRelatedWork W2351072132 @default.
• W3049012004 hasRelatedWork W2362665781 @default.
• W3049012004 hasRelatedWork W2396791681 @default.
• W3049012004 hasRelatedWork W2402232767 @default.

• next