FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3049063650> ?p ?o ?g. }

• W3049063650 endingPage "113276" @default.
• W3049063650 startingPage "113276" @default.
• W3049063650 abstract "Ashwagandha (Withania somnifera (L.) Dunal.) is long known for its sleep-inducing effects. Ashwagandha can be proposed as an alternative to the recommended present treatments for insomnia. This study aimed to evaluate the pharmacological effect of Ashwagandha root extract on sleep in healthy subjects and also in the subjects having insomnia. We performed a randomized, parallel-group, stratified design, placebo-controlled study. A total of 80 eligible participants, 40 in Arm-A (healthy) and 40 in Arm-B (insomnia) were assigned to two groups, either Ashwagandha or placebo and studied for 8-weeks. The assessment was done based on the sleep parameters (Sleep Onset Latency, Total Sleep Time, Wake After Sleep Onset, Total time in bed, and Sleep Efficiency), Pittsburgh Sleep Quality Index and Hamilton Anxiety scale-A questionnaire, mental alertness on rising assessment, and sleep quality questionnaire. Safety and adverse events along with the concomitant medication were also assessed. In both healthy and insomnia subjects, there was a significant improvement in the sleep parameters in the Ashwagandha root extract supplemented group. The improvement was found more significant in insomnia subjects than healthy subjects. Repeat measure Analysis of variance (ANOVA) confirmed the significant improvement in SOL (p 0.013), HAM-A outcomes (p < 0.05), mental alertness (p 0.01), and sleep quality (p < 0.05) of the insomnia patients. A two-way ANOVA was used to confirm the outcomes that denoted sleep onset latency (p < 0.0001) and sleep efficiency (p < 0.0001) as the most improved parameters, followed by TST (p < 0.002) and WASO(p < 0.040). All these parameters (SOL, TST, WASO, TIB, SE, PSQI, HAM-A, Mental Alertness, and Sleep quality) were also statistically assessed for the significant improvement within the group both for the treatment, and the placebo groups in the healthy and the insomnia datasets. Obtained results suggest statistically significant (p < 0.0001) changes between the baseline values and the end of the study results except for the HAM-A and the mental alertness scoresn the healthy subject group. The present study confirms that Ashwagandha root extract can improve sleep quality and can help in managing insomnia. Ashwagandha root extract was well tolerated by all the participants irrespective of their health condition and age. Additional clinical trials are required to generalize the outcome." @default.
• W3049063650 created "2020-08-21" @default.
• W3049063650 creator A5049913574 @default.
• W3049063650 creator A5050094255 @default.
• W3049063650 creator A5055023382 @default.
• W3049063650 creator A5078703036 @default.
• W3049063650 date "2021-01-01" @default.
• W3049063650 modified "2023-10-18" @default.
• W3049063650 title "Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study" @default.
• W3049063650 cites W127750747 @default.
• W3049063650 cites W1707148379 @default.
• W3049063650 cites W1936360328 @default.
• W3049063650 cites W1967113132 @default.
• W3049063650 cites W1982639406 @default.
• W3049063650 cites W1983392743 @default.
• W3049063650 cites W1987720803 @default.
• W3049063650 cites W1992571688 @default.
• W3049063650 cites W1999790218 @default.
• W3049063650 cites W2006664993 @default.
• W3049063650 cites W2013230790 @default.
• W3049063650 cites W2016295144 @default.
• W3049063650 cites W2030710544 @default.
• W3049063650 cites W2037441124 @default.
• W3049063650 cites W2046638406 @default.
• W3049063650 cites W2054646154 @default.
• W3049063650 cites W2063269649 @default.
• W3049063650 cites W2065194709 @default.
• W3049063650 cites W2073460305 @default.
• W3049063650 cites W2073618557 @default.
• W3049063650 cites W2074255145 @default.
• W3049063650 cites W2089280969 @default.
• W3049063650 cites W2111180320 @default.
• W3049063650 cites W2130622748 @default.
• W3049063650 cites W2132320914 @default.
• W3049063650 cites W2135600336 @default.
• W3049063650 cites W2139810582 @default.
• W3049063650 cites W2151487996 @default.
• W3049063650 cites W2156150674 @default.
• W3049063650 cites W2160070901 @default.
• W3049063650 cites W2162532384 @default.
• W3049063650 cites W2166217693 @default.
• W3049063650 cites W2208429249 @default.
• W3049063650 cites W2238415459 @default.
• W3049063650 cites W2328256668 @default.
• W3049063650 cites W2533680877 @default.
• W3049063650 cites W2589834961 @default.
• W3049063650 cites W2884542075 @default.
• W3049063650 cites W2946981645 @default.
• W3049063650 cites W2953583860 @default.
• W3049063650 cites W2974934619 @default.
• W3049063650 cites W2979242114 @default.
• W3049063650 cites W4211099986 @default.
• W3049063650 cites W4231896431 @default.
• W3049063650 cites W4236805817 @default.
• W3049063650 doi "https://doi.org/10.1016/j.jep.2020.113276" @default.
• W3049063650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32818573" @default.
• W3049063650 hasPublicationYear "2021" @default.
• W3049063650 type Work @default.
• W3049063650 sameAs 3049063650 @default.
• W3049063650 citedByCount "20" @default.
• W3049063650 countsByYear W30490636502021 @default.
• W3049063650 countsByYear W30490636502022 @default.
• W3049063650 countsByYear W30490636502023 @default.
• W3049063650 crossrefType "journal-article" @default.
• W3049063650 hasAuthorship W3049063650A5049913574 @default.
• W3049063650 hasAuthorship W3049063650A5050094255 @default.
• W3049063650 hasAuthorship W3049063650A5055023382 @default.
• W3049063650 hasAuthorship W3049063650A5078703036 @default.
• W3049063650 hasConcept C102959455 @default.
• W3049063650 hasConcept C105795698 @default.
• W3049063650 hasConcept C118552586 @default.
• W3049063650 hasConcept C126322002 @default.
• W3049063650 hasConcept C142724271 @default.
• W3049063650 hasConcept C1513209611 @default.
• W3049063650 hasConcept C1862650 @default.
• W3049063650 hasConcept C200678441 @default.
• W3049063650 hasConcept C204787440 @default.
• W3049063650 hasConcept C27081682 @default.
• W3049063650 hasConcept C2776245837 @default.
• W3049063650 hasConcept C2780069950 @default.
• W3049063650 hasConcept C2781053850 @default.
• W3049063650 hasConcept C2781210498 @default.
• W3049063650 hasConcept C2910380747 @default.
• W3049063650 hasConcept C2983189541 @default.
• W3049063650 hasConcept C33923547 @default.
• W3049063650 hasConcept C558461103 @default.
• W3049063650 hasConcept C63759246 @default.
• W3049063650 hasConcept C71924100 @default.
• W3049063650 hasConcept C99476002 @default.
• W3049063650 hasConceptScore W3049063650C102959455 @default.
• W3049063650 hasConceptScore W3049063650C105795698 @default.
• W3049063650 hasConceptScore W3049063650C118552586 @default.
• W3049063650 hasConceptScore W3049063650C126322002 @default.
• W3049063650 hasConceptScore W3049063650C142724271 @default.
• W3049063650 hasConceptScore W3049063650C1513209611 @default.
• W3049063650 hasConceptScore W3049063650C1862650 @default.
• W3049063650 hasConceptScore W3049063650C200678441 @default.
• W3049063650 hasConceptScore W3049063650C204787440 @default.

• next