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• W3049117130 abstract "Photoacoustic (PA) image reconstruction generally utilizes delay-and-sum (DAS) beamforming of received acoustic waves from tissue irradiated with optical illumination. However, nonadaptive DAS reconstructed cardiac PA images exhibit temporally varying noise which causes reduced myocardial PA signal specificity, making image interpretation difficult. Adaptive beamforming algorithms such as minimum variance (MV) with coherence factor (CF) weighting have been previously reported to improve the DAS image quality. In this article, we report on an adaptive beamforming algorithm by extending CF weighting to the temporal domain for preclinical cardiac PA imaging (PAI). The proposed spatiotemporal coherence factor (STCF) considers multiple temporally adjacent image acquisition events during beamforming and cancels out signals with low spatial coherence and temporal coherence, resulting in higher background noise cancellation while preserving the main features of interest (myocardial wall) in the resultant PA images. STCF has been validated using the numerical simulations and in vivo ECG and respiratory-signal-gated cardiac PAI in healthy murine hearts. The numerical simulation results demonstrate that STCF weighting outperforms DAS and MV beamforming with and without CF weighting under different levels of inherent contrast, acoustic attenuation, optical scattering, and signal-to-noise (SNR) of channel data. Performance improvement is attributed to higher sidelobe reduction (at least 5 dB) and SNR improvement (at least 10 dB). Improved myocardial signal specificity and higher signal rejection in the left ventricular chamber and acoustic gel region are observed with STCF in cardiac PAI." @default.
• W3049117130 created "2020-08-21" @default.
• W3049117130 creator A5025522983 @default.
• W3049117130 creator A5070889646 @default.
• W3049117130 date "2021-03-01" @default.
• W3049117130 modified "2023-10-16" @default.
• W3049117130 title "Spatiotemporal Coherence Weighting for <i>In Vivo</i> Cardiac Photoacoustic Image Beamformation" @default.
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• W3049117130 doi "https://doi.org/10.1109/tuffc.2020.3016900" @default.
• W3049117130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8011040" @default.
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• W3049117130 hasPublicationYear "2021" @default.
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