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- W3049156533 abstract "espanolLa tormenta tiroidea es una entidad poco frecuente pero potencialmente mortal que se produce en el contexto de una tirotoxicosis grave con descompensacion sistemica. Se desarrolla en el seno de un hipertiroidismo no diagnosticado o no tratado, y suele precipitarse por un evento agudo como una infeccion, trauma o cirugia. Clinicamente destacan los sintomas cardiovasculares, la taquicardia especialmente, asi como la hipertermia y la alteracion del sistema nervioso central. El diagnostico se basa en criterios clinicos, pues los niveles de hormonas tiroideas no permiten diferenciarla de un hipertiroidismo franco sin complicaciones asociadas. El tratamiento se basa en medidas de soporte, inhibicion farmacologica de la sintesis y liberacion de las hormonas tiroideas (antitiroideos, contrastes yodados o solucion de yodo, glucocorticoides, colestiramina), asi como el bloqueo periferico de su accion (bloqueadores betaadrenergicos). La supervivencia esta relacionada con el diagnostico precoz basado en la sospecha diagnostica y con el inicio inmediato del tratamiento especifico y de soporte, asi como el tratamiento del factor precipitante. EnglishThyroid storm is a rare and life-threatening disorder appearing within severe thyrotoxicosis with systemic decompensation. Acute events, infection, trauma or surgery are the triggering agents. Clinically, cardiovascular symptoms stand out, especially tachycardia, as well as hyperthermia and central nervous system disorders. Since thyroid hormone levels do not allow to differentiating it from frank hyperthyroidism without complications, diagnosis is based on clinical criteria. Treatment is based on support measures, pharmacological inhibition of the synthesis and release of thyroid hormones (antithyroid, iodinated contrasts or iodine solution, glucocorticoids, cholestyramine), as well as peripheral blockade of the hormone action (beta-adrenergic blockers). Survival depends on early diagnosis (based on diagnostic suspicion) and immediate initiation of specific and support treatment accompanied by the treatment of triggering factor." @default.
- W3049156533 created "2020-08-21" @default.
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- W3049156533 date "2020-06-01" @default.
- W3049156533 modified "2023-09-27" @default.
- W3049156533 title "Protocolo diagnóstico y tratamiento de la tormenta tiroidea" @default.
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- W3049156533 doi "https://doi.org/10.1016/j.med.2020.07.005" @default.
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