FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3049203420> ?p ?o ?g. }

• W3049203420 abstract "Abstract Background Postoperative pain after total knee arthroplasty (TKA) and total hip arthroplasty (THA) influence patients’ rehabilitation and life quality. Although gabapentin has been widely used for analgesia, its efficacy is still controversial in TKA and THA. This meta-analysis was performed to assess the efficacy and safety of gabapentin following TKA and THA. Method Electronic databases including PubMed, EMBASE, Cochrane Central Register of Controlled Trials, MEDLINE, and ClinicalTrials.gov were comprehensively retrieved for randomized controlled trials from their inception to June 2019. A total of 7 studies, which compared the administration of gabapentin with that of placebo for the treatment of postoperative pain, were included in our meta-analysis. The meta-analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Result There was no difference in pain score at 24 ( P = 0.87), 48 ( P = 0.15), and 72 ( P = 0.85) h associated with the use of gabapentin. Likewise, no difference in accumulative morphine consumption at 48 h following TKA or THA was found between gabapentin and placebo (DM = − 8.14, 95% CI − 18.55 to 2.28, P = 0.13). The incidence of opioid-related adverse effects, including nausea, pruritus, sedation, and dizziness, is no difference between gabapentin and placebo group. However, subgroup analysis indicated that gabapentin could reduce the incidence of pruritus after TKA (RR = 0.35, 95% CI 0.12 to 0.99, P = 0.05). Conclusion Based on our meta-analysis, gabapentin did not decrease postoperative pain, cumulative morphine consumption, and the incidence of adverse effects after TKA and THA. There was not enough evidence to support the administrations of gabapentin for postoperative pain after TKA and THA." @default.
• W3049203420 created "2020-08-21" @default.
• W3049203420 creator A5001257378 @default.
• W3049203420 creator A5018843234 @default.
• W3049203420 creator A5032325340 @default.
• W3049203420 creator A5040825575 @default.
• W3049203420 creator A5063699981 @default.
• W3049203420 creator A5077429159 @default.
• W3049203420 creator A5088100657 @default.
• W3049203420 creator A5091403179 @default.
• W3049203420 date "2020-08-15" @default.
• W3049203420 modified "2023-10-14" @default.
• W3049203420 title "The efficacy of perioperative gabapentin for the treatment of postoperative pain following total knee and hip arthroplasty: a meta-analysis" @default.
• W3049203420 cites W14086217 @default.
• W3049203420 cites W1535370877 @default.
• W3049203420 cites W168568708 @default.
• W3049203420 cites W1825131280 @default.
• W3049203420 cites W1973660319 @default.
• W3049203420 cites W2017566567 @default.
• W3049203420 cites W2023012278 @default.
• W3049203420 cites W2086752162 @default.
• W3049203420 cites W2100082403 @default.
• W3049203420 cites W2154777653 @default.
• W3049203420 cites W2171935112 @default.
• W3049203420 cites W2402398382 @default.
• W3049203420 cites W2469235540 @default.
• W3049203420 cites W2470673251 @default.
• W3049203420 cites W2473442302 @default.
• W3049203420 cites W2517000100 @default.
• W3049203420 cites W2736873897 @default.
• W3049203420 cites W2773261190 @default.
• W3049203420 cites W2798267505 @default.
• W3049203420 cites W2804917639 @default.
• W3049203420 cites W2853637417 @default.
• W3049203420 cites W2895470650 @default.
• W3049203420 cites W2899425687 @default.
• W3049203420 cites W2904231350 @default.
• W3049203420 cites W3014385091 @default.
• W3049203420 cites W4231899502 @default.
• W3049203420 cites W4241672734 @default.
• W3049203420 cites W71209042 @default.
• W3049203420 doi "https://doi.org/10.1186/s13018-020-01849-6" @default.
• W3049203420 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7429897" @default.
• W3049203420 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32799902" @default.
• W3049203420 hasPublicationYear "2020" @default.
• W3049203420 type Work @default.
• W3049203420 sameAs 3049203420 @default.
• W3049203420 citedByCount "15" @default.
• W3049203420 countsByYear W30492034202021 @default.
• W3049203420 countsByYear W30492034202022 @default.
• W3049203420 countsByYear W30492034202023 @default.
• W3049203420 crossrefType "journal-article" @default.
• W3049203420 hasAuthorship W3049203420A5001257378 @default.
• W3049203420 hasAuthorship W3049203420A5018843234 @default.
• W3049203420 hasAuthorship W3049203420A5032325340 @default.
• W3049203420 hasAuthorship W3049203420A5040825575 @default.
• W3049203420 hasAuthorship W3049203420A5063699981 @default.
• W3049203420 hasAuthorship W3049203420A5077429159 @default.
• W3049203420 hasAuthorship W3049203420A5088100657 @default.
• W3049203420 hasAuthorship W3049203420A5091403179 @default.
• W3049203420 hasBestOaLocation W30492034201 @default.
• W3049203420 hasConcept C126322002 @default.
• W3049203420 hasConcept C141071460 @default.
• W3049203420 hasConcept C142724271 @default.
• W3049203420 hasConcept C168563851 @default.
• W3049203420 hasConcept C197934379 @default.
• W3049203420 hasConcept C204787440 @default.
• W3049203420 hasConcept C27081682 @default.
• W3049203420 hasConcept C2776608144 @default.
• W3049203420 hasConcept C2776814716 @default.
• W3049203420 hasConcept C2777389121 @default.
• W3049203420 hasConcept C2778336525 @default.
• W3049203420 hasConcept C2780580376 @default.
• W3049203420 hasConcept C31174226 @default.
• W3049203420 hasConcept C42219234 @default.
• W3049203420 hasConcept C71924100 @default.
• W3049203420 hasConcept C95190672 @default.
• W3049203420 hasConceptScore W3049203420C126322002 @default.
• W3049203420 hasConceptScore W3049203420C141071460 @default.
• W3049203420 hasConceptScore W3049203420C142724271 @default.
• W3049203420 hasConceptScore W3049203420C168563851 @default.
• W3049203420 hasConceptScore W3049203420C197934379 @default.
• W3049203420 hasConceptScore W3049203420C204787440 @default.
• W3049203420 hasConceptScore W3049203420C27081682 @default.
• W3049203420 hasConceptScore W3049203420C2776608144 @default.
• W3049203420 hasConceptScore W3049203420C2776814716 @default.
• W3049203420 hasConceptScore W3049203420C2777389121 @default.
• W3049203420 hasConceptScore W3049203420C2778336525 @default.
• W3049203420 hasConceptScore W3049203420C2780580376 @default.
• W3049203420 hasConceptScore W3049203420C31174226 @default.
• W3049203420 hasConceptScore W3049203420C42219234 @default.
• W3049203420 hasConceptScore W3049203420C71924100 @default.
• W3049203420 hasConceptScore W3049203420C95190672 @default.
• W3049203420 hasFunder F4320321001 @default.
• W3049203420 hasIssue "1" @default.
• W3049203420 hasLocation W30492034201 @default.
• W3049203420 hasLocation W30492034202 @default.
• W3049203420 hasLocation W30492034203 @default.
• W3049203420 hasOpenAccess W3049203420 @default.
• W3049203420 hasPrimaryLocation W30492034201 @default.

• next