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- W3049205880 abstract "There are very few treatment options that modify the course of osteoarthritis (OA) of the hand; the only current treatment options are physiotherapy and analgesics. At the moment, OA is regarded as a disease of the entire joint, with involvement of cartilage, bone, synovium, ligaments and muscles and new treatment options can focus on these structures. In a double-blind, placebo-controlled trial, treatment of patients with inflammatory OA of the hand (with pain, soft-tissue swelling and an ultrasound picture characteristic of inflammation) with 10 mg prednisolone per day for 6 weeks resulted in a larger decrease in pain than placebo did. This short-term study does certainly not provide the definitive answer for treating this chronic disease, and long-term use of prednisolone is associated with several side-effects. Nevertheless, this breakthrough study clearly demonstrates that the use of anti-inflammatory, anti-rheumatic medication may have a favourable effect on inflammatory OA of the hand. Studies of anti-inflammatory drugs with a better long-term safety profile will be welcome." @default.
- W3049205880 created "2020-08-21" @default.
- W3049205880 creator A5075695885 @default.
- W3049205880 date "2020-07-16" @default.
- W3049205880 modified "2023-09-27" @default.
- W3049205880 title "[Is osteoarthritis an inflammatory disease after all?; prednisolone effective in osteoarthritis of the hand]." @default.
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