Matches in SemOpenAlex for { <https://semopenalex.org/work/W3049270180> ?p ?o ?g. }
- W3049270180 endingPage "40739" @default.
- W3049270180 startingPage "40728" @default.
- W3049270180 abstract "Aiming at developing a moderate and efficient sono-photodynamic therapy for breast cancer, tissue engineering scaffolds may provide an easy and efficient strategy to eliminate serious side effects in conventional surgery or chemotherapy, and thus, they are highly desired. However, the development of ideal sono-photodynamic therapeutic scaffolds is always hindered by the poor stability and incompatibility between the different biomaterial components. Herein, the Food and Drug Administration (FDA)-approved sono/photosensitizer Chlorin e6 (Ce6) was successfully and tightly incorporated into electrospun polycaprolactone/gelatin (PG) scaffolds via positively charged protonated g-C3N4 nanosheets (pCN). The PG fibers were precoated with graphene oxide (GO) to enable the assembly of pCN on the surface through electrostatic interactions. The Ce6@pCN-GO-PG composite scaffolds exhibited good cytocompatibility and excellent sono-photodynamic activity, leading to distinctly boosted reactive oxygen species (ROS) generation and a 95.8% inactivation rate of breast cancer cells through a synergistic sono-photodynamic process triggered by an 808 nm laser and 1 MHz ultrasound (US) excitation, within the clinical therapeutic dose. The as-developed scaffolds with unique ultrasound cavitation therapeutic effects can be used not only for complete eradication of tumor cells after surgery but also as a cell behavior observation platform of sono-photodynamic cancer therapy." @default.
- W3049270180 created "2020-08-21" @default.
- W3049270180 creator A5006118312 @default.
- W3049270180 creator A5014772022 @default.
- W3049270180 creator A5023367573 @default.
- W3049270180 creator A5039514844 @default.
- W3049270180 creator A5040932288 @default.
- W3049270180 creator A5043181323 @default.
- W3049270180 creator A5048200579 @default.
- W3049270180 creator A5070373092 @default.
- W3049270180 creator A5075562934 @default.
- W3049270180 date "2020-08-14" @default.
- W3049270180 modified "2023-10-13" @default.
- W3049270180 title "Co-Immobilization of Ce6 Sono/Photosensitizer and Protonated Graphitic Carbon Nitride on PCL/Gelation Fibrous Scaffolds for Combined Sono-Photodynamic Cancer Therapy" @default.
- W3049270180 cites W1192952131 @default.
- W3049270180 cites W1596334311 @default.
- W3049270180 cites W1596848781 @default.
- W3049270180 cites W1780657167 @default.
- W3049270180 cites W1819242049 @default.
- W3049270180 cites W1922419400 @default.
- W3049270180 cites W1969573130 @default.
- W3049270180 cites W1976840096 @default.
- W3049270180 cites W1979946545 @default.
- W3049270180 cites W1981060678 @default.
- W3049270180 cites W1996218409 @default.
- W3049270180 cites W2014750067 @default.
- W3049270180 cites W2023230705 @default.
- W3049270180 cites W2028034445 @default.
- W3049270180 cites W2030713573 @default.
- W3049270180 cites W2042258668 @default.
- W3049270180 cites W2046235637 @default.
- W3049270180 cites W2047688825 @default.
- W3049270180 cites W2051822076 @default.
- W3049270180 cites W2082306789 @default.
- W3049270180 cites W2094302888 @default.
- W3049270180 cites W2098161381 @default.
- W3049270180 cites W2120153364 @default.
- W3049270180 cites W2126415088 @default.
- W3049270180 cites W2128332568 @default.
- W3049270180 cites W2162505178 @default.
- W3049270180 cites W2164133842 @default.
- W3049270180 cites W2199892936 @default.
- W3049270180 cites W2277655379 @default.
- W3049270180 cites W2402191886 @default.
- W3049270180 cites W2465658363 @default.
- W3049270180 cites W2547699807 @default.
- W3049270180 cites W2549272242 @default.
- W3049270180 cites W2571527387 @default.
- W3049270180 cites W2587137754 @default.
- W3049270180 cites W2588144396 @default.
- W3049270180 cites W2664931613 @default.
- W3049270180 cites W2733738837 @default.
- W3049270180 cites W2747084009 @default.
- W3049270180 cites W2754902399 @default.
- W3049270180 cites W2761809061 @default.
- W3049270180 cites W2767583865 @default.
- W3049270180 cites W2771639621 @default.
- W3049270180 cites W2774759944 @default.
- W3049270180 cites W2789641767 @default.
- W3049270180 cites W2800025005 @default.
- W3049270180 cites W2800980552 @default.
- W3049270180 cites W2801645489 @default.
- W3049270180 cites W2802122104 @default.
- W3049270180 cites W2888456951 @default.
- W3049270180 cites W2888836855 @default.
- W3049270180 cites W2889171861 @default.
- W3049270180 cites W2891943108 @default.
- W3049270180 cites W2893205419 @default.
- W3049270180 cites W2897682227 @default.
- W3049270180 cites W2900991758 @default.
- W3049270180 cites W2901826600 @default.
- W3049270180 cites W2903171792 @default.
- W3049270180 cites W2903340064 @default.
- W3049270180 cites W2906846914 @default.
- W3049270180 cites W2908589039 @default.
- W3049270180 cites W2913432098 @default.
- W3049270180 cites W2929581451 @default.
- W3049270180 cites W2932767860 @default.
- W3049270180 cites W2937387706 @default.
- W3049270180 cites W2938932754 @default.
- W3049270180 cites W2939714203 @default.
- W3049270180 cites W2940738540 @default.
- W3049270180 cites W2943898729 @default.
- W3049270180 cites W2945390283 @default.
- W3049270180 cites W2945962488 @default.
- W3049270180 cites W2970361527 @default.
- W3049270180 cites W2972467260 @default.
- W3049270180 cites W2972629861 @default.
- W3049270180 cites W2974318432 @default.
- W3049270180 cites W2995288860 @default.
- W3049270180 cites W2995542929 @default.
- W3049270180 cites W2995705344 @default.
- W3049270180 cites W3006603650 @default.
- W3049270180 cites W3015775334 @default.
- W3049270180 cites W3021260977 @default.
- W3049270180 cites W3037086989 @default.
- W3049270180 doi "https://doi.org/10.1021/acsami.0c08446" @default.
- W3049270180 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32794726" @default.