FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3049351520> ?p ?o ?g. }

• W3049351520 endingPage "108818" @default.
• W3049351520 startingPage "108818" @default.
• W3049351520 abstract "Mycoplasma synoviae is one of the economically most significant avian Mycoplasma species. It can cause great financial losses to the poultry industry by inducing respiratory diseases, infectious synovitis, or eggshell apex abnormalities. There are different approaches to control M. synoviae infection. Although antimicrobial therapy cannot replace long-term solutions, like eradication and vaccination, this strategy can be effective in the short term, as adequate antibiotic treatment can relieve economic losses through the attenuation of clinical signs and reduction of transmission. Using broth microdilution method, minimal inhibitory concentration (MIC) values to fourteen antibiotics related to eight antimicrobial groups were determined in 96 M. synoviae strains. Whole genome sequencing and sequence analysis revealed mutations potentially associated with decreased susceptibility to fluoroquinolones, macrolides and lincomycin. Molecular markers responsible for the high MICs to fluoroquinolones were found in the gyrA, gyrB, parC and parE genes. Besides, single nucleotide polymorphisms identified in genes encoding the 23S rRNA were found to be responsible for high MICs to the 50S inhibitor macrolides and lincomycin, while amino acid change in the 50S ribosomal protein L22 could be associated with decreased susceptibility to macrolides. The revealed mutations can contribute to the extension of knowledge about the genetic background of antibiotic resistance in M. synoviae. Moreover, the explored potentially resistance-related mutations may serve as targets for molecular biological assays providing data of antibiotic susceptibility prior to the laborious and time-consuming isolation of M. synoviae strains." @default.
• W3049351520 created "2020-08-21" @default.
• W3049351520 creator A5014550989 @default.
• W3049351520 creator A5025093794 @default.
• W3049351520 creator A5050941901 @default.
• W3049351520 creator A5055556611 @default.
• W3049351520 creator A5057977389 @default.
• W3049351520 creator A5059169127 @default.
• W3049351520 creator A5064636951 @default.
• W3049351520 creator A5066895711 @default.
• W3049351520 creator A5067838402 @default.
• W3049351520 creator A5073944050 @default.
• W3049351520 creator A5074401641 @default.
• W3049351520 creator A5081213334 @default.
• W3049351520 creator A5084183934 @default.
• W3049351520 date "2020-09-01" @default.
• W3049351520 modified "2023-10-18" @default.
• W3049351520 title "Mutations potentially associated with decreased susceptibility to fluoroquinolones, macrolides and lincomycin in Mycoplasma synoviae" @default.
• W3049351520 cites W1951848410 @default.
• W3049351520 cites W1963768313 @default.
• W3049351520 cites W1972891378 @default.
• W3049351520 cites W1976672951 @default.
• W3049351520 cites W1982566730 @default.
• W3049351520 cites W1999458074 @default.
• W3049351520 cites W2006092569 @default.
• W3049351520 cites W2009596137 @default.
• W3049351520 cites W2013073820 @default.
• W3049351520 cites W2023571364 @default.
• W3049351520 cites W2049279089 @default.
• W3049351520 cites W2056458905 @default.
• W3049351520 cites W2061898396 @default.
• W3049351520 cites W2088074800 @default.
• W3049351520 cites W2092173116 @default.
• W3049351520 cites W2102885994 @default.
• W3049351520 cites W2114260822 @default.
• W3049351520 cites W2120902911 @default.
• W3049351520 cites W2128880918 @default.
• W3049351520 cites W2133112837 @default.
• W3049351520 cites W2135110560 @default.
• W3049351520 cites W2136140016 @default.
• W3049351520 cites W2283827090 @default.
• W3049351520 cites W2514261101 @default.
• W3049351520 cites W2535421482 @default.
• W3049351520 cites W2559432659 @default.
• W3049351520 cites W2768310190 @default.
• W3049351520 cites W2770547684 @default.
• W3049351520 cites W2883730734 @default.
• W3049351520 cites W2989157446 @default.
• W3049351520 cites W4236786088 @default.
• W3049351520 doi "https://doi.org/10.1016/j.vetmic.2020.108818" @default.
• W3049351520 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32891024" @default.
• W3049351520 hasPublicationYear "2020" @default.
• W3049351520 type Work @default.
• W3049351520 sameAs 3049351520 @default.
• W3049351520 citedByCount "5" @default.
• W3049351520 countsByYear W30493515202020 @default.
• W3049351520 countsByYear W30493515202021 @default.
• W3049351520 countsByYear W30493515202022 @default.
• W3049351520 crossrefType "journal-article" @default.
• W3049351520 hasAuthorship W3049351520A5014550989 @default.
• W3049351520 hasAuthorship W3049351520A5025093794 @default.
• W3049351520 hasAuthorship W3049351520A5050941901 @default.
• W3049351520 hasAuthorship W3049351520A5055556611 @default.
• W3049351520 hasAuthorship W3049351520A5057977389 @default.
• W3049351520 hasAuthorship W3049351520A5059169127 @default.
• W3049351520 hasAuthorship W3049351520A5064636951 @default.
• W3049351520 hasAuthorship W3049351520A5066895711 @default.
• W3049351520 hasAuthorship W3049351520A5067838402 @default.
• W3049351520 hasAuthorship W3049351520A5073944050 @default.
• W3049351520 hasAuthorship W3049351520A5074401641 @default.
• W3049351520 hasAuthorship W3049351520A5081213334 @default.
• W3049351520 hasAuthorship W3049351520A5084183934 @default.
• W3049351520 hasBestOaLocation W30493515201 @default.
• W3049351520 hasConcept C104317684 @default.
• W3049351520 hasConcept C159047783 @default.
• W3049351520 hasConcept C176947019 @default.
• W3049351520 hasConcept C2778838687 @default.
• W3049351520 hasConcept C2778985905 @default.
• W3049351520 hasConcept C2780685696 @default.
• W3049351520 hasConcept C2780950330 @default.
• W3049351520 hasConcept C2781151156 @default.
• W3049351520 hasConcept C2910317154 @default.
• W3049351520 hasConcept C40749294 @default.
• W3049351520 hasConcept C501593827 @default.
• W3049351520 hasConcept C54355233 @default.
• W3049351520 hasConcept C67705224 @default.
• W3049351520 hasConcept C86803240 @default.
• W3049351520 hasConcept C88478588 @default.
• W3049351520 hasConcept C89423630 @default.
• W3049351520 hasConcept C94665300 @default.
• W3049351520 hasConceptScore W3049351520C104317684 @default.
• W3049351520 hasConceptScore W3049351520C159047783 @default.
• W3049351520 hasConceptScore W3049351520C176947019 @default.
• W3049351520 hasConceptScore W3049351520C2778838687 @default.
• W3049351520 hasConceptScore W3049351520C2778985905 @default.
• W3049351520 hasConceptScore W3049351520C2780685696 @default.
• W3049351520 hasConceptScore W3049351520C2780950330 @default.
• W3049351520 hasConceptScore W3049351520C2781151156 @default.

• next