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- W3049399997 abstract "4502 Introduction: Forkhead box protein 3 (Foxp3) controls the development and function of CD4+/CD25+ T-regulatory cells (Tregs). The role of Tregs in tolerance or suppression of malignancy is not well understood. Intratumoral accumulation of Tregs was associated with poor survival in ovarian cancer but improved survival in patients with hematologic malignancy. In this study we examined Foxp3 expression levels in tumor-positive and -negative sentinel nodes (SNs) and in non-SNs (NSNs) from patients with early-stage melanoma. Methods: RNA was extracted from freshly dissected and preserved tangential cut peripheral tissue sections of 21 tumor-negative SNs, 18 tumor-positive SNs (micrometastases" @default.
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- W3049399997 date "2008-05-01" @default.
- W3049399997 modified "2023-09-24" @default.
- W3049399997 title "Prognostic significance of Foxp3 expression from sentinel and nonsentinel nodes in melanoma" @default.
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